{"id":8204,"date":"2016-08-18T14:43:16","date_gmt":"2016-08-18T05:43:16","guid":{"rendered":"http:\/\/seigi.accsnet.ne.jp\/sigh\/blog\/?p=8204"},"modified":"2021-12-21T14:12:11","modified_gmt":"2021-12-21T05:12:11","slug":"8204","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=8204","title":{"rendered":"\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66"},"content":{"rendered":"<p>\u300c<a href=\"http:\/\/blog.livedoor.jp\/obokata_file-stap\/\" target=\"_blank\" rel=\"noopener\">\u5c0f\u4fdd\u65b9\u6674\u5b50\u3055\u3093\u3078\u306e\u4e0d\u6b63\u306a\u5831\u9053\u3092\u8ffd\u53ca\u3059\u308b\u6709\u5fd7\u306e\u4f1a<\/a>\u300d\u3068\u3044\u3046\u30c7\u30bf\u30e9\u30e1\u3092\u3076\u3061\u307e\u3051\u3066\u3044\u308b\u4e0a\u7530\u306e\u30b5\u30a4\u30c8\u306e\u300c<a href=\"http:\/\/blog.livedoor.jp\/obokata_file-stap\/archives\/1060247545.html\" target=\"_blank\" rel=\"noopener\">2016\u5e7408\u670816\u65e5 \u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u304cSTAP\u7d30\u80de\u8ad6\u6587\u3092\u5f15\u7528\uff3f\u764c\u7d30\u80de\u3092\u9178\u6027\u6d74\u3067\u591a\u80fd\u6027\u78ba\u8a8d<\/a>\u300d\u3068\u3044\u3046\u8a18\u4e8b\u306e\u201d\u307f\u306b\u304f\u3055\u201d\u306f\u300c<a href=\"http:\/\/blog.livedoor.jp\/peter_cetera\/\" target=\"_blank\" rel=\"noopener\">\u300c\u7d50\u8ad6\u3042\u308a\u304d\u300d\u306e\u975e\u5c02\u9580\u5bb6\u30d6\u30ed\u30b0\u304c\u793e\u4f1a\u3092\u6df7\u4e71\u3055\u305b\u3066\u3044\u308b\uff1a\u4e16\u754c\u4e09\u5927\u4e0d\u6b63STAP\u4e8b\u4ef6\u306e\u6b63\u3057\u3044\u7406\u89e3\u3092\u793e\u4f1a\u306b\u5e83\u3081\u308b\u4f1a<\/a>\u300d\u306e\u300c<a href=\"http:\/\/blog.livedoor.jp\/peter_cetera\/archives\/6091818.html\" target=\"_blank\" rel=\"noopener\">2016\u5e7408\u670816\u65e5<\/a>\u300d\u306e\u8a18\u4e8b\u306b\u3042\u308b\u901a\u308a\u306a\u306e\u3067\u3001\u3053\u3053\u3067\u3042\u3089\u305f\u3081\u3066\u8ffd\u52a0\u3059\u308b\u3053\u3068\u306f\u306a\u3044\u3002\u3053\u306e\u8a18\u4e8b\u306b\u3042\u308b\u8ad6\u6587\u306e\uff14\u540d\u306e\u8457\u8005\u306f\u5b66\u90e8\u5185\u306e\u6240\u5c5e\u90e8\u9580\u306f\u7570\u306a\u308b\u3082\u306e\u306e\u3001\u3059\u3079\u3066\u7c73\u56fd\u30df\u30ba\u30fc\u30ea\u5dde\u30bb\u30f3\u30c8\u30eb\u30a4\u30b9\u306b\u3042\u308b\u30bb\u30f3\u30c8\u30eb\u30a4\u30b9\u30fb\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u533b\u5b66\u90e8\u6240\u5c5e\uff08Washington University in St. Louis School of Medicine, St. Louis, Missouri, 63110, USA\uff09\u3067\u3042\u308b\u3002<br \/>\n\u3053\u306e\u4e0a\u7530\u306e\u8a18\u4e8b\u306b\u4f55\u6545\u304b\u690d\u7269\u767a\u751f\u30fb\u907a\u4f1d\u5b66\u306e\u9ce5\u5c45\u656c\u5b50\u6c0f\u306e\u30c4\u30a4\u30c3\u30bf\u30fc\u8a18\u4e8b\u304c\u8cbc\u308a\u4ed8\u3051\u3089\u308c\u3066\u3044\u308b\u3002\u30c4\u30a4\u30fc\u30c8\u306e\u5185\u5bb9\u306f\u4f8b\u306e2014\u5e74\uff15\u6708\u306b\u5f01\u8b77\u58eb\u304c\u516c\u958b\u3057\u305f\u5c0f\u4fdd\u65b9\u5b9f\u9a13\u30ce\u30fc\u30c8\u306b\u3064\u3044\u3066\u3067\u3001\u7d75\u65e5\u8a18\u30fb\u5c0f\u5b66\u6821\u306e\u590f\u4f11\u307f\u306e\u5bbf\u984c\u2212\u671d\u9854\u89b3\u5bdf\u65e5\u8a18\u2212\u307f\u305f\u3044\u3060\u30fb\u305d\u308c\u3088\u308a\u3072\u3069\u3044\u3068\u591a\u304f\u306e\u7814\u7a76\u8005\u304c\u5446\u308c\u8fd4\u3063\u305f\u3084\u3064\u3060\u3002<br \/>\n<a href=\"https:\/\/nbsigh2.com\/wp-content\/uploads\/2016\/08\/20160818KTorii_Twitter.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-8205 size-thumbnail\" src=\"https:\/\/nbsigh2.com\/wp-content\/uploads\/2016\/08\/20160818KTorii_Twitter-150x150.png\" alt=\"20160818KTorii_Twitter\" width=\"150\" height=\"150\" \/><\/a><br \/>\n\u306a\u305c\u3053\u306e\u30c4\u30a4\u30fc\u30c8\u304c\u30b3\u30d4\u30da\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u5168\u304f\u610f\u5473\u4e0d\u660e\u3067\u3042\u308b\u3002\u9ce5\u5c45\u6c0f\u306f\u7c73\u56fd\u306e\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u6240\u5c5e\u3060\u304c\u30bb\u30f3\u30c8\u30eb\u30a4\u30b9\u3067\u306f\u306a\u304f\u30b7\u30a2\u30c8\u30eb\u306b\u3042\u308b\u307b\u3046\uff08University of Washington, Seattle, WA 98195\uff09\u3060\u3002\u3053\u3063\u3061\u306b\u3082\u533b\u5b66\u90e8\u306f\u3042\u308b\u304c\u3001\u9ce5\u5c45\u6c0f\u306f\u751f\u7269\u5b66\uff08Department of Biology\uff09\u3060\u3002\u7c73\u56fd\u306b\u306f<a href=\"https:\/\/ja.wikipedia.org\/wiki\/%E3%83%AF%E3%82%B7%E3%83%B3%E3%83%88%E3%83%B3%E5%A4%A7%E5%AD%A6\" target=\"_blank\" rel=\"noopener\">\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u304c\uff17\u3064<\/a>\u3082\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u306b\u76f4\u63a5\u306e\u95a2\u4fc2\u306f\u306a\u3044\u3068\u601d\u3046\u306e\u3060\u304c\u3002<br \/>\n\u7ba1\u7406\u4eba\u304c\u540d\u524d\u3060\u3051\u306f\u77e5\u3063\u3066\u3044\u308b\u306e\u306f\u30bb\u30f3\u30c8\u30eb\u30a4\u30b9\u3068\u30b7\u30a2\u30c8\u30eb\u306e\uff12\u3064\u3060\u304c\u3001\u5358\u306b\u7814\u7a76\u4e0a\u306e\u53cb\u4eba\u304c\u3044\u308b\u3068\u304b\u3001\u76f4\u63a5\u6307\u5c0e\u3057\u3066\u3044\u305f\u308f\u3051\u3067\u306f\u306a\u3044\u3051\u3069\u3088\u304f\u77e5\u3063\u3066\u3044\u308b\u5b66\u751f\u304c\u30dd\u30b9\u30c9\u30af\u306b\u306a\u3063\u3066\u3044\u308b\u304b\u3089\u3068\u304b\u3044\u3046\u3053\u3068\u3060\u3051\u3060\u3002<br \/>\n<span style=\"line-height: 1.5;\">\u4f55\u6545\u3001\u8cbc\u308a\u4ed8\u3051\u305f\u3093\u3060\u308d\uff1f\u5c0f\u4fdd\u65b9\u306e\u7d75\u65e5\u8a18\u306f\u8a18\u4e8b\u3068\u95a2\u4fc2\u306a\u3044\u3060\u308d\u3002\u65e5\u672c\u8a9e\u306b\u3057\u305f\u3068\u304d\u306e\u300c\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u300d\u3057\u304b\u5171\u901a\u9805\u306f\u306a\u3044\u3002\u82f1\u8a9e\u3067\u306f\u5171\u901a\u9805\u306b\u306a\u3089\u306a\u3044\u3002\u30b8\u30e3\u30fc\u30ca\u30ea\u30b9\u30c8\u306a\u3093\u3060\u304b\u3089\u306a\u3002\u4e00\u6b21\u8cc7\u6599\u3092\u8abf\u3079\u3066\u7269\u3092\u66f8\u3051\u3088\u306a\u3002<\/span><br \/>\n\u4e0a\u7530\u306e\u30da\u30fc\u30b8\u306e\u30b3\u30d4\u30fc\u3060\u3002[wpdm_file id=8]<br \/>\n\u64c1\u8b77\u6d3e\u306e\u7686\u3055\u3093\u3002\u305d\u308d\u305d\u308d\u3053\u306e\u6728\u661f\u3053\u3068\u4e0a\u7530\u6c0f\u3068\u306f\u7e01\u3092\u5207\u3063\u305f\u307b\u3046\u304c\u5c0f\u4fdd\u65b9\u64c1\u8b77\u306e\u76ee\u7684\u306b\u6cbf\u3046\u306e\u3067\u306f\uff1f<\/p>\n<blockquote><p>[ \u8ffd\u8a18 ] 2016.8.20\u3000<span style=\"color: #ff0000;\">\u5168\u304f\u610f\u5473\u4e0d\u660e\u3067\u3042\u308b<\/span><br \/>\n\u3053\u306e\u30d6\u30ed\u30b0\u3092\u8aad\u3093\u3060<a href=\"http:\/\/giveme5.hateblo.jp\/entry\/2016\/08\/19\/%E6%9C%A8%E6%98%9F%E3%81%95%E3%82%93%E3%81%AF%E3%80%81%E3%81%AA%E3%81%9C%E9%B3%A5%E5%B1%85%E6%95%AC%E5%AD%90%E3%81%95%E3%82%93%E3%82%92%E7%A3%94%E3%81%AB%E3%81%97%E3%81%9F%E3%81%AE%E3%81%8B%3F\" target=\"_blank\" rel=\"noopener\">\u72f8\u3055\u3093\u304c\u89e3\u8aac\u3057\u3066<\/a>\u304f\u308c\u3066\u3044\u308b\u3002\u305d\u306e\u901a\u308a\u306a\u306e\u3060\u304c\u3001\u300c\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u3066\u3044\u3063\u3071\u3044\u3042\u308b\u3088\u300d\u3068\u793a\u3059\u3060\u3051\u3067\u3001\u76f4\u88c1\u7684\u306b\u3048\u3052\u3064\u306a\u304f\u66f8\u304f\u3053\u3068\u306f\u305b\u305a\u3001\u3042\u3048\u3066\u610f\u5473\u4e0d\u660e\u3068\u66f8\u3044\u305f\u308f\u3051\u3060\u3002\u3059\u3050\u610f\u5473\u306f\u308f\u304b\u308b\u3068\u601d\u3063\u305f\u304b\u3089\u3060\u3002\u72f8\u3055\u3093\u306e\u89e3\u8aac\u304c\u3048\u3052\u3064\u306a\u3044\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u306a\u3044\u3088\u3002\u72f8\u3055\u3093\u306e\u3088\u3046\u306a\u8868\u73fe\u306f\u3053\u306e\u30d6\u30ed\u30b0\u3067\u306f\u3057\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u3060\u3051\u3060\u3002<br \/>\n\u3055\u3089\u306b[ \u8ffd\u8a18 ] 2016.8.20<br \/>\n\u3069\u3046\u3084\u3089\u64c1\u8b77\u6d3e\u306e<a href=\"http:\/\/lunedi.sblo.jp\/article\/176493937.html\" target=\"_blank\" rel=\"noopener\">\u767d\u9ce5\u6e05\u6c34\u3068\u304b\u3044\u3046\u8f29\u304c\u300c\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u300d\u3068\u5358\u7d14\u306b\u8a33\u3059\u3068\u8907\u6570\u306e\u5927\u5b66\u306e\u533a\u5225\u304c\u3064\u304b\u306a\u304f\u306a\u3063\u3061\u3083\u3046\u3068\u3044\u3046\u3053\u3068\u3092\u77e5\u3089\u305a<\/a>\u306b\u6728\u661f\u3053\u3068\u4e0a\u7530\u306bSTAP\u8ad6\u6587\u304c\u5f15\u7528\u3055\u308c\u3066\u3044\u308b\u3068\u5fa1\u6ce8\u9032\u3057\u305f\u3053\u3068\u304c\u767a\u7aef\u306e\u3088\u3046\u3060\u3002\u4e0a\u7530\u304c\u30ef\u30b7\u30f3\u30c8\u30f3\u5927\u5b66\u3092\u30ad\u30fc\u30ef\u30fc\u30c9\u306b\u3057\u3066\u5c0f\u4fdd\u65b9\u6279\u5224\u306e\u9ce5\u5c45\u6c0f\u3092\u3001\u72f8\u3055\u3093\u306e\u89e3\u8aac\u306b\u3042\u308b\u3088\u3046\u306a\u610f\u56f3\u3067\u3001\u78d4\u306b\u3057\u305f\u3089\u3057\u3044\u3002\u6307\u6458\u3055\u308c\u3066\u4e0a\u7530\u306f\u3061\u3087\u3063\u3074\u308a\u5909\u66f4\u3057\u305f\u304c\u3001\u305d\u3082\u305d\u3082\u9ce5\u5c45\u6c0f\u306e\u30c4\u30a3\u30fc\u30c8\u3092\u30b3\u30d4\u30da\u3059\u308b\u610f\u5473\u306f\u306a\u3044\u304b\u3089\u3001\u524a\u9664\u3059\u308c\u3070\u3044\u3044\u306e\u306b\u63b2\u8f09\u3057\u305f\u307e\u307e\u3060\u3002\u3060\u304b\u3089\u306a\u3093\u3060\u304b\u308f\u304b\u3089\u3093\u8a18\u4e8b\u306b\u306a\u3063\u3066\u3057\u307e\u3063\u305f\u307e\u307e\u3060\u3002\u307e\u305f\u767d\u9ce5\u3068\u306f\u6728\u661f\u306e\u30d6\u30ed\u30b0\u3067\u306f\u5236\u9650\u3068\u3044\u3046\u30cf\u30f3\u30c9\u30eb\u3067\u30b3\u30e1\u30f3\u30c8\u3057\u3066\u3044\u308b\u3089\u3057\u3044\u3002\u4e0a\u7530\u304c\u7121\u77e5\u306a\u306e\u3060\u304b\u3089\u6b63\u3057\u304f\u60c5\u5831\u3092\u4f1d\u3048\u308b\u3079\u304d\u306a\u306e\u3060\u304c\u3001\u767d\u9ce5\u306e\u65b9\u3082\u82f1\u6587\u8ad6\u6587\u306f\u81ea\u52d5\u7ffb\u8a33\u306b\u983c\u308b\u304f\u3089\u3044\u3060\u304b\u3089\u60c5\u5831\u3092\u6b63\u3057\u304f\u4f1d\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u306e\u3060\u308d\u3046\u3002\u307e\u3001\u64c1\u8b77\u6d3e\u306e\u9023\u4e2d\u306b\u306f\u3053\u3093\u306a\u7a0b\u5ea6\u306e\u304c\u591a\u3044\u3093\u3060\u3088\u306d\u3002<\/p><\/blockquote>\n<p>\u64a4\u56de\u3055\u308c\u305f\u8ad6\u6587\u306e\u5f15\u7528\u306b\u3064\u3044\u3066\u306f\u8b70\u8ad6\u304c\u3042\u308b\u3002\u4e00\u7814\u7a76\u8005\u30fb\u6559\u80b2\u8005\u306e\u30d6\u30ed\u30b0\u3067\u9060\u85e4\u6c0f\u306e\u8ad6\u6587\u306b\u3064\u3044\u3066\u8b70\u8ad6\u3055\u308c\u3066\u3044\u305f\u3051\u3069\u3001\u64a4\u56de\u3055\u308c\u305f\u8ad6\u6587\u306e\u5185\u5bb9\u3092positive\u306a\u610f\u5473\u3067\u5f15\u7528\u3059\u308b\u306e\u306f\u9593\u9055\u3044\u3060\u308d\u3046\u3002\u64a4\u56de\u3055\u308c\u305f\u306e\u3060\u304b\u3089\u3001\u3069\u306e\u30c7\u30fc\u30bf\u304c\u6b63\u3057\u3044\u304b\u308f\u304b\u3089\u306a\u3044\u308f\u3051\u3067\u3001\u307e\u305f\u7acb\u3066\u305f\u4eee\u8aac\u3082\u691c\u8a3c\u3067\u304d\u305f\u308f\u3051\u3067\u306f\u306a\u3044\u304b\u3089\u610f\u5473\u304c\u306a\u3044\u30fb\u5984\u60f3\u3060\u304b\u3089\u3060\u3002\u4eca\u56de\u306e<a href=\"http:\/\/www.nature.com\/articles\/srep27803\" target=\"_blank\" rel=\"noopener\">\u554f\u984c\u3068\u306a\u3063\u305f\u8ad6\u6587<\/a>\u304c\u64a4\u56de\u3055\u308c\u305fNature\u8ad6\u6587\u3092\u5f15\u7528\u3057\u305f\u90e8\u5206\u3092\u898b\u308b\u3068\u300cStress based in vitro OCT-4 expression has been reported previously for stem cells14,21\u300d\u3067\u300121\u304c\u64a4\u56de\u3055\u308c\u305fNature\u8ad6\u6587\u3060\u3002\u4f53\u7d30\u80de\u3092\u9162\u306b\u6652\u3059\u3068Oct-4\u304c\u767a\u73fe\u3059\u308b\u3068\u3044\u3046\u7d50\u679c\u306f\u3001\u64a4\u56de\u3055\u308c\u3066\u3044\u3066\u672c\u5f53\u304b\u3069\u3046\u304b\u308f\u304b\u3089\u306a\u3044\u304b\u3089\u5f15\u7528\u3059\u308b\u306b\u76f8\u5fdc\u3057\u304f\u306a\u3044\u3002\u3053\u306e\u8ad6\u6587\u306e\u30c6\u30fc\u30de\u304c\u9178\u6027\u74b0\u5883\u3067\u816b\u760d\u306e\u5468\u56f2\u306e\u7e4a\u7dad\u82bd\u7d30\u80de\u306bOct-4\u304c\u767a\u73fe\u3057\u305f\u3068\u3044\u3046\u3053\u3068\u306a\u306e\u3067\u5f15\u7528\u3057\u305f\u3044\u3060\u308d\u3046\u3051\u3069\u524d\u4f8b\u3068\u3057\u3066\u3075\u3055\u308f\u3057\u3044\u8ad6\u6587\u3067\u306f\u306a\u3044\u3002Received:<time datetime=\"2016-02-08\">08 February 2016\u3060\u304b\u3089\u64a4\u56de\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u305f\u306f\u305a\u3060\u3002<\/time><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\t\t\t\t<![CDATA[]]>\t\t<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8],"tags":[],"class_list":["post-8204","post","type-post","status-publish","format-standard","hentry","category-education","category-fake"],"_links":{"self":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/8204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8204"}],"version-history":[{"count":1,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/8204\/revisions"}],"predecessor-version":[{"id":21366,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/8204\/revisions\/21366"}],"wp:attachment":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}