{"id":7756,"date":"2016-05-28T17:45:40","date_gmt":"2016-05-28T08:45:40","guid":{"rendered":"http:\/\/seigi.accsnet.ne.jp\/sigh\/blog\/?p=7756"},"modified":"2021-12-21T11:42:53","modified_gmt":"2021-12-21T02:42:53","slug":"%e3%81%8a%e5%ac%a2%e3%81%95%e3%82%93%e3%81%ae%e5%8d%9a%e5%a3%ab%e8%ab%96%e6%96%87%e3%81%ae%e3%83%86%e3%83%a9%e3%83%88%e3%83%bc%e3%83%9e","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=7756","title":{"rendered":"\u304a\u5b22\u3055\u3093\u306e\u535a\u58eb\u8ad6\u6587\u306e\u30c6\u30e9\u30c8\u30fc\u30de"},"content":{"rendered":"<p><a href=\"http:\/\/seigi.accsnet.ne.jp\/sigh\/blog\/?p=7680#comments\" target=\"_blank\" rel=\"noopener\">\u30a2\u30ce\u59d0\u3055\u3093\u304b\u3089\u30b3\u30e1\u30f3\u30c8<\/a>\u3092\u3044\u305f\u3060\u3044\u3066\u3001\u3069\u3046\u601d\u3046\uff1f\u3068\u805e\u304b\u308c\u305f\u306e\u3067&#8230;\u30b3\u30e1\u30f3\u30c8\u6b04\u306b\u8fd4\u305d\u3046\u3068\u601d\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u9577\u304f\u306a\u3063\u3061\u3083\u3063\u305f\u306e\u3067\u3002<br \/>\n\u304a\u304b\u3057\u306a\u3068\u3053\u308d\u304c\u3042\u3063\u305f\u3089\u30b3\u30e1\u30f3\u30c8\u304f\u3060\u3055\u3044\u306a\u3002<br \/>\n\u30c6\u30e9\u30c8\u30fc\u30de\u3067\u3059\u304c\u3001<a href=\"http:\/\/stapcells.blogspot.jp\/\" target=\"_blank\" rel=\"noopener\">11jigen\u3055\u3093\u306e\u30da\u30fc\u30b8<\/a>\uff08http:\/\/stapcells.blogspot.jp\/\uff09\u306b\u3042\u308b\u535a\u58eb\u8ad6\u6587\u306e\u30c6\u30e9\u30c8\u30fc\u30de\u306e\u56f3\uff08Fig.14)\u306e\u00a0legend\u00a0\u306f\u300cFigure 14 <strong>Teratoma like<\/strong> mass from bone marow spheres &#8230;\u300d\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u306e\u3067\u3001\u300c\u3042\u306e\u65e5\u300d\u306e\uff15\uff15\u30da\u30fc\u30b8\u306e\u300c\u7d44\u7e54\u5de5\u5b66\u306e\u6280\u8853\u3092\u3064\u304b\u3063\u3066<strong>\u30c6\u30e9\u30c8\u30fc\u30de\u306b\u4f3c\u305f<\/strong>\u7d44\u7e54\u3092\u4f5c\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u300d\u3068\u8a18\u8ff0\u306f\u4e00\u81f4\u3057\u3066\u3044\u307e\u3059\u3002\u535a\u58eb\u8ad6\u6587\u672c\u6587\u306b\u30c6\u30e9\u30c8\u30fc\u30de\u304c\u3067\u304d\u305f\u3068\u3044\u3046\u8a18\u8ff0\u304c\u3042\u308b\u304b\u3069\u3046\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\uff08\u5f8c\u8ff0\u306e\u3088\u3046\u306b\u672c\u6587\u306b\u8a18\u8f09\u304c\u306a\u3044\u306e\u304b\u3082\u3057\u308c\u307e\u305b\u3093\uff09\u3002<a href=\"http:\/\/www.waseda.jp\/jp\/news14\/data\/140717_committee_report.pdf\uff09\" target=\"_blank\" rel=\"noopener\">\u65e9\u7a32\u7530\u5927\u5b66\u306e\u535a\u58eb\u8ad6\u6587\u306e\u8abf\u67fb<\/a>\uff08\u4e0b\u8a18\uff09\u3067\u306f\u30c6\u30e9\u30c8\u30fc\u30de\u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u3066\u30c6\u30e9\u30c8\u30fc\u30de\u69d8\u7d44\u7e54\uff08\u7d30\u80de\u584a\uff09\u3068\u30c6\u30e9\u30c8\u30fc\u30de\u306e\u533a\u5225\u306f\u3067\u304d\u3066\u3044\u307e\u305b\u3093\u3002<br \/>\n\u3053\u306e\u535a\u8ad6\u306e\u56f3\uff11\uff14\u3092Nature Article \u8ad6\u6587\u3000Nature 505, 641\u2013647, 2014\uff09\u306eFig.2e\u306e\u514d\u75ab\u67d3\u8272\u306e\u4e0b\u6bb5\uff13\u679a\u306b\u6d41\u7528\u3057\u305f\u308f\u3051\u3067\u3001Nature \u306e\u3053\u306e\u56f3\u306e legend \u3067\u306f\u300cTeratoma formation assay of day 7 clusters of Oct4-GFP+ cells.\u300d\u3068\u3042\u308a\u3001\u3053\u3061\u3089\u306f\u9aa8\u9ac4\u3068\u813e\u81d3\u3068\u3044\u3046\u7531\u6765\u306e\u9055\u3044\u306e\u4ed6\u306b\u3082\u300clike\u3000\u69d8\u300d\u304c\u306a\u3044\u3068\u3044\u3046\u5927\u5618\u3064\u304d\u3060\u3063\u305f\u308f\u3051\u3067\u3059\u3002<br \/>\n\u3055\u3066\u3001\u300c\u3042\u306e\u65e5\u300d\u306b\u3088\u308b\u3068\u3001Vacanti \u7814\u7a76\u5ba4\u3067\u306f\u300c\u30c6\u30e9\u30c8\u30fc\u30de\u306b\u4f3c\u305f\u7d44\u7e54\u300d\u3057\u304b\u3067\u304d\u305a\u3001PNAS\u306b\u6295\u7a3f\u3057\u305f\u8ad6\u6587\u306freject\u3055\u308c\u305f\u308f\u3051\u3067\u3059\u306d\u3002\u30ad\u30e1\u30e9\u3092\u4f5c\u308c\u3068\u8a00\u308f\u308c\u3001\uff12\uff10\uff11\uff10\u5e74\uff17\u6708\u306b\u5f53\u6642\u7406\u7814\u306e\u82e5\u5c71\u6c0f\u3068\u30ad\u30e1\u30e9\u306e\u76f8\u8ac7\u306e\u305f\u3081\u9762\u4f1a\u3057\u305f\u308f\u3051\u3067\u3059\u3002\u3053\u306e\u65e5\u304b\u3089\u540c\u5e74\uff11\uff12\u6708\u306e\u535a\u58eb\u8ad6\u6587\u3092\u4f5c\u6210\u3059\u308b\u307e\u3067\u306e\u9593\u3001\u3055\u3089\u306b\u30ad\u30e1\u30e9\u304c\u3067\u304d\u308b\uff12\uff10\uff11\uff11\u5e74\uff11\uff11\u6708\uff08<a href=\"http:\/\/www3.riken.jp\/stap\/j\/c13document14.pdf\" target=\"_blank\" rel=\"noopener\">CDB \u81ea\u5df1\u70b9\u691c\u306e\u691c\u8a3c\u306b\u3064\u3044\u3066<\/a>\u3000http:\/\/www3.riken.jp\/stap\/j\/c13document14.pdf\uff09\u307e\u3067\u30c6\u30e9\u30c8\u30fc\u30de\u306e\u5b9f\u9a13\u3092\u884c\u3063\u305f\u3068\u306e\u8a18\u8ff0\u306f\u3069\u3053\u306b\u3082\u306a\u3044\u3088\u3046\u3067\u3059\u3002\u3053\u306e\u9593\u306f\u30ad\u30e1\u30e9\u4f5c\u6210\u306b\u96c6\u4e2d\u3057\u3066\u3044\u305f\u3068\u601d\u308f\u308c\u307e\u3059\u3002\u535a\u58eb\u8ad6\u6587\u306e\u63d0\u51fa\u306f\uff12\uff10\uff11\uff11\u5e74\uff12\u6708\u3067\u3059\u3002<br \/>\n\u6b21\u306b\u30c6\u30e9\u30c8\u30fc\u30de\u306b\u3064\u3044\u3066\u8a71\u984c\u306b\u306a\u3063\u3066\u3044\u308b\u306e\u306f\u3001STAP\u7d30\u80de\u3092\u4f7f\u3063\u305f\u5b9f\u9a13\u3067\u3001\u535a\u58eb\u53f7\u53d6\u5f97\u5f8c\u306e\u7406\u7814\u3067\u884c\u3063\u305f\u3082\u306e\u3067\u3059\u306d\u3002\uff12\uff10\uff11\uff11\u5e74\uff11\uff12\u6708\uff12\uff17\u65e5\u306b\u79fb\u690d\u3001\uff12\uff10\uff11\uff12\u5e74\uff11\u6708\uff12\uff14\u65e5\u306b\u53d6\u308a\u51fa\u3057\u305f\u5b9f\u9a13\u3067\u3059\u3002\u4f8b\u306e\u5b9f\u9a13\u30ce\u30fc\u30c8\u306e\u6f2b\u753b\u306e\u3084\u3064\u3067\u3059\u3002\u305d\u3057\u3066\uff12\uff10\uff11\uff12\u5e74\uff12\u6708\u672b\u3053\u308d\u514d\u75ab\u67d3\u8272\u3092\u304a\u3053\u306a\u3063\u305f\uff08\u753b\u50cfB\u306e\uff1f\uff09\u305d\u3057\u3066\uff16\u6708\u306b\u5199\u771f\u64ae\u5f71\u3057\u305f\uff08\u753b\u50cfB)\u3068\u3044\u3046\u306e\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u7406\u7814\u8abf\u67fb\u59d4\u54e1\u4f1a\u304c\u30c6\u30e9\u30c8\u30fc\u30de\u306fES\u7d30\u80de\u3060\u3063\u305f\u3068\u5224\u5b9a\u3057\u305f\u306e\u306f\u3001\u3053\u306e\uff12\uff10\uff11\uff11\u5e74\uff11\uff12\u6708\u4ee5\u964d\u306b\u3001\u7406\u7814\u3067\u4f5c\u6210\u3057\u305f\u6a19\u672c\u3067\u3059\u306d\u3002<br \/>\n\u300c\u3042\u306e\u65e5\u300d\u306e\uff16\uff12\u30da\u30fc\u30b8\u306b\u306f\u3001\u82e5\u5c71\u6c0f\u306b\u9762\u4f1a\u306b\u884c\u304f\u524d\u306e\u5927\u548c\u6c0f\u306e\u767a\u8a00\u3068\u3057\u3066\u300c\u3053\u3061\u3089\u306b\u306fES\u7d30\u80de\u3068\u304b\u305d\u3046\u3044\u3046\u7814\u7a76\u5206\u91ce\u306e\u5c02\u9580\u5bb6\u306f\u3044\u306a\u3044\u3057\u3001\u307f\u305f\u3053\u3068\u3082\u306a\u3044&#8230;\u300d\u3068\u3042\u308b\u306e\u3067\u3001\u65e9\u7a32\u7530\u3001\u6771\u4eac\u5973\u5b50\u533b\u79d1\u5927\u5b66\u3001Vacanti\u7814\u7a76\u5ba4\u306b\u306fES\u7d30\u80de\u306f\u306a\u304b\u3063\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u535a\u8ad6\u306e\u30c6\u30e9\u30c8\u30fc\u30de\uff08\u69d8\u7d30\u80de\u584a\uff09\u306fES\u7d30\u80de\u3067\u306f\u306a\u3044\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<strong>[ \u8ffd\u8a18 2016.5.30 ]\u4e0b\u8a18\u30b3\u30e1\u30f3\u30c8\u306b\u3042\u308a\u307e\u3059\u3088\u3046\u306bES\u7d30\u80de\u3060\u3063\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002TE\u8ad6\u6587\u306b\u672c\u5f53\u306bES\u7d30\u80de\u3092\u4f7f\u3063\u305f\u3068\u3057\u305f\u3089\u5927\u548c\u6c0f\u306e\u767a\u8a00\u304c\u30c7\u30bf\u30e9\u30e1\u304b\u3001\u304a\u5b22\u3055\u3093\u304c\u5927\u548c\u6c0f\u306e\u767a\u8a00\u3092\u5275\u4f5c\u3057\u305f\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/strong><br \/>\n\u65e9\u7a32\u7530\u5927\u5b66\u306e\u8abf\u67fb\u66f8\uff08<a href=\"http:\/\/www.waseda.jp\/jp\/news14\/data\/140717_committee_report.pdf\" target=\"_blank\" rel=\"noopener\">\u5927\u5b66\u9662\u5148\u9032\u7406\u5de5\u5b66\u7814\u7a76\u79d1\u306b\u304a\u3051\u308b\u535a\u58eb\u5b66\u4f4d\u8ad6\u6587\u306b\u95a2\u3059\u308b\u8abf\u67fb\u59d4\u54e1\u4f1a<\/a>\u3000\u5e73\u6210 26 \u5e74 7 \u6708 17 \u65e5\u3000http:\/\/www.waseda.jp\/jp\/news14\/data\/140717_committee_report.pdf\uff09\u3067\u306e\u30c6\u30e9\u30c8\u30fc\u30de\u306b\u3064\u3044\u3066\u306f\u3001\uff12\uff12\u30da\u30fc\u30b8\u306b<\/p>\n<blockquote><p>\u672c\u4ef6\u535a\u58eb\u8ad6\u6587\u672c\u6587\u306b\u306f\u3001\u3053\u306e\u753b\u50cf\u306b\u5bfe\u5fdc\u3059\u308b\u8a18\u8f09\u306f\u5b58\u5728\u305b\u305a\u3001\u307e\u305f\u554f\u984c\u7b87\u6240\u246a\u306b\u8a18\u8f09\u3055\u308c\u305f\u8aac\u660e\u6587\u306b\u3088\u3063\u3066\u3082\u3001\u3055\u3089\u306b\u305d\u306e\u4ed6\u306e\u672c\u4ef6\u535a\u58eb\u8ad6\u6587\u306b\u8a18\u8f09\u3055\u308c\u305f\u672c\u6587\u3001\u56f3\u7b49\u306b\u3088\u3063\u3066\u3055\u3048\u3082\u3001\u554f\u984c\u7b87\u6240\u246a\uff08Fig. 14 \u306e\u4e0a\u6bb5\u306e 3 \u679a\u306e\u5199\u771f\uff09\u306e\u610f\u5473\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u3002\u3088\u3063\u3066\u3001\u610f\u5473\u4e0d\u660e\u306a\u8a18\u8f09\u3068\u3044\u3048\u308b\u3002<\/p><\/blockquote>\n<p>\u306e\u307b\u304b\u306b\u306f\u63d0\u51fa\u8ad6\u6587\u3068\u30b9\u30e9\u30a4\u30c9\u767a\u8868\u306e\u56f3\u3068\u306e\u5dee\u7570\u7b49\u306b\u3064\u3044\u3066\u306e\u8a18\u8f09\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u30c6\u30e9\u30c8\u30fc\u30de\u5b9f\u9a13\u304c\u3069\u306e\u3088\u3046\u306b\u306a\u3055\u308c\u305f\u304b\u306e\u8b70\u8ad6\u306f\u306a\u3044\u3067\u3059\u306d\u3002\u5b9f\u9a13\u30ce\u30fc\u30c8\u306fVacanti\u7814\u7a76\u5ba4\u306b\u3042\u308b\u306e\u3067\u63d0\u51fa\u3067\u304d\u306a\u3044\u3068\u3044\u3046\u4e3b\u5f35\u304c\u306a\u3055\u308c\u305f\u308f\u3051\u3067\u3001\u3069\u306e\u3088\u3046\u306a\u5b9f\u9a13\u3067\u3053\u306e\u56f3\u304c\u5f97\u3089\u308c\u305f\u306e\u304b\u3092\u88cf\u4ed8\u3051\u308b\u3082\u306e\u306f\u793a\u3055\u308c\u3066\u3044\u306a\u3088\u3046\u3067\u3059\u3002<br \/>\n\u3055\u3066\u3001\u4ee5\u4e0a\u306e\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001\u535a\u58eb\u8ad6\u6587\u306e\u30c6\u30e9\u30c8\u30fc\u30de\uff08\u69d8\u7d30\u80de\u584a\uff09\u306f\u306a\u3093\u3060\u3063\u305f\u3093\u3067\u3057\u3087\uff1f<br \/>\n\uff08\uff11\uff09\u30b9\u30d5\u30a7\u30a2\u7d30\u80de\u3092\u79fb\u690d\u3057\u305f\u7d50\u679c\u3060\u3002<br \/>\n\uff08\uff12\uff09\u57f9\u990a\u7b4b\u7d30\u80de\u306e\u5199\u771f\u3068\u304b\u3092\u3069\u3063\u304b\u306e\u30da\u30fc\u30b8\u304b\u3089\u30b3\u30d4\u30da\u3057\u3066\u304d\u305f\u306e\u3068\u540c\u69d8\u306b\u76d7\u4f5c\u3060\u3002<br 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