{"id":28612,"date":"2026-09-16T07:29:13","date_gmt":"2026-09-15T22:29:13","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=28612"},"modified":"2026-09-16T07:29:13","modified_gmt":"2026-09-15T22:29:13","slug":"%e3%81%84%e3%81%84%e3%81%8c%e3%81%8b%e3%82%8a-2","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=28612","title":{"rendered":"\u3044\u3044\u304c\u304b\u308a"},"content":{"rendered":"

\u5b9f\u7528\u65e5\u672c\u8a9e\u8868\u73fe\u8f9e\u5178\u306b\u3088\u308b\u3068\u3001\u8a00\u3044\u304c\u304b\u308a\u3068\u306f\u300c\u8a00\u3044\u304c\u304b\u308a\u3068\uff08\u3044\u3044\u304c\u304b\u308a\uff09\u306f\u3001\u4ed6\u4eba\u306e\u8a00\u52d5\u306b\u5bfe\u3057\u3066\u7121\u7406\u3084\u308a\u975e\u96e3\u3084\u6279\u5224\u3092\u3059\u308b\u884c\u70ba\u3092\u6307\u3059\u8a00\u8449\u3067\u3042\u308b\u3002\u3053\u306e\u884c\u70ba\u306f\u3001\u76f8\u624b\u306e\u610f\u56f3\u3084\u4e8b\u5b9f\u3068\u306f\u7570\u306a\u308b\u89e3\u91c8\u3092\u5f37\u8981\u3057\u3001\u305d\u306e\u7d50\u679c\u3001\u4e0d\u5fc5\u8981\u306a\u5bfe\u7acb\u3084\u6469\u64e6\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u8a00\u3044\u304c\u304b\u308a\u306f\u3001\u4e00\u822c\u7684\u306b\u306f\u793e\u4f1a\u7684\u306a\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u969c\u5bb3\u3068\u898b\u306a\u3055\u308c\u3001\u516c\u5e73\u306a\u5bfe\u8a71\u3084\u7406\u89e3\u3092\u963b\u5bb3\u3059\u308b\u8981\u7d20\u3068\u3057\u3066\u8a8d\u8b58\u3055\u308c\u3066\u3044\u308b\u3002 \u8a00\u3044\u304c\u304b\u308a\u306b\u306f\u3001\u4eba\u9593\u95a2\u4fc2\u306e\u4e2d\u3067\u306e\u30d1\u30ef\u30fc\u30cf\u30e9\u30b9\u30e1\u30f3\u30c8\u3084\u3044\u3058\u3081\u3001\u5bb6\u5ead\u5185\u306e\u5bfe\u4eba\u95a2\u4fc2\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u72b6\u6cc1\u3067\u898b\u3089\u308c\u308b\u3002\u307e\u305f\u3001\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u4e0a\u3067\u3082\u3001SNS\u3084\u63b2\u793a\u677f\u306a\u3069\u3067\u7121\u7406\u306a\u975e\u96e3\u3084\u6279\u5224<\/strong>\u304c\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u3082\u8a00\u3044\u304c\u304b\u308a\u3068\u547c\u3070\u308c\u308b\u3053\u3068\u304c\u3042\u308b\u3002
\n<\/a>\u3067\u3042\u308b\u3002\u4ed6\u306e\u8f9e\u5178\u304c1,2\u884c\u3067\u8aac\u660e\u3057\u3066\u3044\u308b\u306e\u306b\u304f\u3089\u3079\u4e01\u5be7\u306a\u8aac\u660e\u3067\u3042\u308b\u3002<\/p>\n

STAP\u8ad6\u6587Article\u306eFig.3b\u306b\u3064\u3044\u3066\u6842\u8abf\u67fb\u59d4\u54e1\u4f1a\u304c\u554f\u984c\u306b\u3057\u305f\u308f\u3051\u3067\u3059\uff08\u5831\u544a\u66f8p22\uff09\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u660e\u8996\u91ce\u3068Oct4-GFP\u306e\u86cd\u5149\u3092\u767a\u5149\u3055\u305b\u305f\u56f3\u304c\u540c\u4e00\u8996\u91ce\u3067\u306a\u3044\u3068\u6307\u6458\u3057\u305f\u308f\u3051\u3067\u3059\u3002
\n\u3000\u3053\u306e\u56f3\u306f\u9178\u6d74\u3059\u308b\u3068\u521d\u671f\u5316\u3055\u308c\u308b\u3068\u3044\u3046\u65b0\u767a\u898b\u306e\u8a3c\u62e0\u306e\u4e00\u3064\u3068\u3057\u3066\u3001\u9178\u306b\u66b4\u9732\u3059\u308b\u3068\u521d\u671f\u5316\u95a2\u9023\u907a\u4f1d\u5b50\u306eOct4\u304c\u767a\u73fe\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3082\u306e\u3067\u3001\u53f3\u5074\u306eLow-pH-treated cells\u306f\u660e\u8996\u91ce\uff08\u4e0a\uff09\u3067\u898b\u3048\u308b\u7d30\u80de\uff0f\u7d30\u80de\u584a\u304c\u86cd\u5149\u3092\u898b\u308b\u3068\uff08\u4e0b\uff09\u4e0a\u3067\u898b\u3089\u308c\u308b\u7d30\u80de\u584a\u304c\u7dd1\u306b\u767a\u5149\u3057\u3066\u3044\u308b\uff1dOct4\u304c\u767a\u73fe\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u56f3\u3067\u3059\u3002\u3064\u307e\u308a\u4e0a\u4e0b\u306f\u540c\u3058\u8996\u91ce\u306e\u5199\u771f\u3067\u767a\u5149\u3057\u3066\u3044\u308b\u306e\u306a\u3089\u4f55\u304c\u767a\u5149\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u793a\u3057\u3066\u3044\u308b\u3082\u306e\u3067\u3059\u3002\u4e0a\u4e0b\u306e\u5199\u771f\u306f\u30da\u30a2\u3067\u306a\u3044\u3068\u610f\u5473\u304c\u306a\u3044\u306e\u3067\u3059\u3002
\n\u3000\u5de6\u306eControl\u306f\u9178\u306b\u66b4\u9732\u3057\u306a\u304b\u3063\u305f\u6a19\u672c\u3067\u3001\u86cd\u5149\u304c\u307f\u3089\u308c\u306a\u3044\uff1dOct4\u304c\u767a\u73fe\u3057\u3066\u3044\u306a\u3044\uff1d\u521d\u671f\u5316\u3055\u308c\u3066\u306a\u3044\u3068\u3044\u3046\u6a19\u672c\u3067\u3001\u4e0b\u306f\u86cd\u5149\u3092\u767a\u3059\u308b\u7269\u304c\u306a\u3044\uff1d\u771f\u3063\u9ed2\u3068\u3044\u3046\u308f\u3051\u3067\u3059\u3002\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u306f\u3044\u3048\u3053\u3061\u3089\u3082\u4e0a\u4e0b\u304c\u30da\u30a2\u306b\u306a\u3063\u3066\u306a\u3044\u3068\u610f\u5473\u304c\u306a\u3044\u306e\u3067\u3059\u3002\u660e\u8996\u91ce\u3067\u7d30\u80de\u3092\u898b\u305b\u3001\u306a\u306b\u3082\u306a\u3044\u3068\u3053\u308d\u306e\u86cd\u5149\u5199\u771f\u3092\u307f\u305b\u3066\u3082\u610f\u5473\u304c\u306a\u3044\u308f\u3051\u3067\u3059\u3002
\n\u3000\u5b9f\u969b\u306b\u306f\u3053\u306e\u7dd1\u306e\u86cd\u5149\u306f\u7d30\u80de\u304c\u6b7b\u306c\u6642\u306b\u898b\u305b\u308b\u81ea\u5bb6\u86cd\u5149\u3067\u3042\u3063\u305f\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001\u76f8\u6fa4\u691c\u8a3c\u5b9f\u9a13\uff08https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4995676\/\uff09\u306eFig.1\u306e\u3088\u3046\u306b\u306e\u3088\u3046\u306b\u5b9f\u306f\u7dd1\u301c\u8d64\u3068\u3044\u3046\u5e83\u7bc4\u56f2\u306e\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u306e\u86cd\u5149\u3092\u767a\u3057\u3066\u3044\u308b\u306e\u306b\u7dd1\u306e\u30d5\u30a3\u30eb\u30bf\u30fc\u3092\u4ecb\u3059\u308b\u304b\u3089\u7dd1\u306e\u86cd\u5149\u3060\u3051\u304c\u3067\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u305f\u3060\u3051\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u306e\u3067\u3059\u3002<\/p>\n

\u3055\u3066\u3001\u8457\u8005\u306e\u3044\u3044\u305f\u3044\u3053\u3068\u306f\u4e0a\u306e\u3088\u3046\u306a\u306e\u3067\u3001\u3053\u306e\u5206\u91ce\u3068\u3044\u3046\u304b\u79d1\u5b66\u8ad6\u6587\u3067\u306f\u5199\u771f\u306e\u4e0a\u4e0b\u306f\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u3053\u3068\u306f\u5f53\u305f\u308a\u524d\u306a\u306e\u3067\u3059\u3002\u300cFig.3b\u306b\u3064\u3044\u3066\u300cBright-field\u3068Oct4-GFP\u304c\u540c\u4e00\u8996\u91ce\u306e\u5bfe\u5fdc\u753b\u50cf\u3067\u3042\u308b\u3068\u306f\u8ad6\u6587\u306b\u306a\u3044\u3002\u300d<\/span><\/a>\u3068\u3044\u3046\u5b66\u3068\u307f\u5b50\u306e\u30af\u30ec\u30fc\u30e0\u306f\u8ad6\u5916\u306a\u306e\u3067\u3059\u3002\u3082\u3057\u3053\u3068\u306a\u308b\u8996\u91ce\u306e\u5199\u771f\u3060\u3068\u3057\u305f\u3089\u8a50\u6b3a\u884c\u70ba\u3067\u3001\u8ab0\u3082\u3057\u307e\u305b\u3093\u3002\u771f\u3063\u9ed2\u306a\u306a\u306b\u3082\u5199\u3063\u3066\u306a\u3044\u5199\u771f\u304c\u6b32\u3057\u3044\u3068\u4f55\u3082\u306a\u3044\u3068\u3053\u308d\u3092\u3055\u3064\u3048\u3044\u3057\u305f\u3089\u3001\u3042\u308b\u3044\u306f\u86cd\u5149\u306e\u611f\u5ea6\u3092\u304b\u3048\u3066\u64ae\u5f71\u3057\u305f\u3089\u4e0d\u6b63\u884c\u70ba\u3067\u3059\u3002\u8aad\u8005\u306f\u3053\u306e\u7a2e\u306e\u5199\u771f\u306f\u540c\u4e00\u8996\u91ce\u3068\u89e3\u91c8\u3057\u3066\u8aad\u3080\u306e\u304c\u5f53\u305f\u308a\u524d\u306a\u306e\u3067\u3059\u304b\u3089\u8aad\u8005\u3092\u3060\u307e\u3057\u3066\u3044\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002
\n\u3000\u6842\u8abf\u67fb\u59d4\u54e1\u4f1a\u306f\u30aa\u30ea\u30b8\u30ca\u30eb\u5199\u771f\u3092\u8981\u6c42\u3057\u305f\u306e\u306b\u5c0f\u4fdd\u65b9\u6c0f\u306f\u63d0\u51fa\u3057\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u304c\u3001\u5c0f\u4fdd\u65b9\u6c0f\u7121\u77e5\u3060\u3063\u305f\u3001\u30d5\u30a1\u30a4\u30eb\u306e\u7ba1\u7406\u304c\u3067\u304d\u3066\u306a\u304b\u3063\u305f\u3068\u3057\u3066\u4e0d\u6b63\u884c\u70ba\u3068\u3057\u306a\u304b\u3063\u305f\u308f\u3051\u3067\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u304c\u300c\u307e\u305a\u78ba\u8a8d\u3059\u3079\u304d\u306a\u306e\u306f\u3001\u8ad6\u6587\u306b\u63b2\u8f09\u3055\u308c\u305fBright-field\u753b\u50cf\u3068Oct4-GFP\u753b\u50cf\u304c\u3001\u3082\u3068\u3082\u3068\u540c\u4e00\u8996\u91ce\u306e\u5bfe\u5fdc\u753b\u50cf\u3068\u3057\u3066\u63d0\u793a\u3055\u308c\u305f\u3082\u306e\u306a\u306e\u304b\u3069\u3046\u304b\u3067\u3042\u308b\u3002\u300d<\/span>\u3068\u3044\u3046\u306e\u306f\u3001\u3053\u306e\u696d\u754c\u3067\u306f\u540c\u4e00\u8996\u91ce\u306a\u306e\u304c\u5f53\u305f\u308a\u524d\u3067\u3001\u3044\u3061\u3044\u3061\u8a18\u8f09\u3057\u306a\u3044\u308f\u3051\u3067\u3001\u304a\u9580\u9055\u3044\u3067\u3059\u3002ChatGPT\u306b\u805e\u3044\u3066\u307f\u307e\u3057\u305f\u3002\u7d50\u679c\u3092\u4ee5\u4e0b\u306e\uff0a\u3067\u793a\u3057\u307e\u3059\u3002\u5f53\u305f\u308a\u524d\u3067\u3059\u304c\u3001\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u8a18\u3059\u308b\u306e\u306f\u671b\u307e\u3057\u3044\u304c\u3001\u306a\u304f\u3066\u3082\u8aad\u8005\u304c\u8aa4\u8aad\u3059\u308b\u3053\u3068\u306f\u306a\u3044\u3057\u3001\u8ad6\u6587\u306e\u67fb\u8aad\u3082\u901a\u308b\u3001\u3053\u3093\u306a\u30af\u30ec\u30fc\u30e0\u3092\u3064\u3051\u308b\u306e\u306f\u4e0d\u81ea\u7136\u3060\u3001\u5b66\u3068\u307f\u5b50\u306e\u30af\u30ec\u30fc\u30e0\u306f\u4e0a\u8a18\u306e\u7121\u7406\u306a\u975e\u96e3\u3084\u6279\u5224<\/strong>\u306b\u8a72\u5f53\u3059\u308b\u6842\u8abf\u67fb\u59d4\u54e1\u4f1a\u306b\u5bfe\u3059\u308b\u3044\u3044\u304c\u304b\u304b\u308a\u30fb\u30a4\u30c1\u30e3\u30e2\u30f3<\/strong>\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\uff0a<\/p>\n

Q\uff11\uff1a\u3000STAP\u8ad6\u6587\u306eArticle\u306eFig.3b \u306e\u56f3\uff08\u6dfb\u4ed8\uff09\u3067\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u9178\u66b4\u9732\u3044\u305a\u308c\u3082\u305d\u308c\u305e\u308c\u4e0a\u4e0b\u304c\u660e\u8996\u91ce\u3068\u86cd\u5149\u767a\u5149\u306e\u5199\u771f\u306e\u540c\u4e00\u8996\u91ce\u306e\u5199\u771f\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u306b\u3064\u3044\u3066\u3001\u5b66\u3068\u307f\u5b50\u3055\u3093\u306f\u300cFig.3b\u306b\u3064\u3044\u3066\u300cBright-field\u3068Oct4-GFP\u304c\u540c\u4e00\u8996\u91ce\u306e\u5bfe\u5fdc\u753b\u50cf\u3067\u3042\u308b\u3068\u306f\u8ad6\u6587\u306b\u306a\u3044\u3002\u300c\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u300d\u3068\u8ad6\u6587\u304c\u660e\u8a18\u3057\u3066\u3044\u306a\u3044\u4ee5\u4e0a\u3001\u753b\u50cf\u3060\u3051\u304b\u3089\u540c\u4e00\u8996\u91ce\u3060\u3063\u305f\u3068\u65ad\u5b9a\u3059\u308b\u3053\u3068\u3082\u3001\u9006\u306b\u540c\u4e00\u8996\u91ce\u3067\u306f\u306a\u304b\u3063\u305f\u3068\u65ad\u5b9a\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u306f\u305a\u3060\u3002\u300d\u3068\u3044\u3046\u610f\u898b\u3092\u8ff0\u3079\u307e\u3057\u305f\uff08https:\/\/katura1.blog.fc2.com\/blog-entry-3197.html\uff09\u3002\u3057\u304b\u3057\u305f\u3081\u606f\u3055\u3093\u306f\u300c\u3053\u306e\u5206\u91ce\u306e\u7814\u7a76\u3067\u3053\u306e\u7a2e\u306e\u5199\u771f\u306f\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u306e\u304c\u5f53\u305f\u308a\u524d\u3060\u304b\u3089\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u3053\u3068\u3092\u660e\u8a18\u3059\u308b\u3053\u3068\u306f\u3042\u3063\u305f\u307b\u3046\u304c\u3044\u3044\u304c\u5fc5\u9808\u3067\u306f\u306a\u3044\u3001\u8ad6\u6587\u306e\u4e3b\u65e8\u304b\u3089\u8aad\u8005\u306f\u300c\u660e\u8a18\u3055\u308c\u3066\u3044\u306a\u3044\u304b\u3089\u5225\u8996\u91ce\u304b\u3082\u3057\u308c\u306a\u3044\u300d\u3068\u901a\u5e38\u8aad\u3080\u3053\u3068\u306f\u306a\u3044\u3002\u300d\u3068\u30b3\u30e1\u30f3\u30c8\u3057\u307e\u3057\u305f\u3002\u5e38\u8b58\u7684\u306b\u306f\u3069\u3061\u3089\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

ChatGPT\uff1a\u3000\u5e38\u8b58\u7684\u306b\u306f\u3001**\u305f\u3081\u606f\u3055\u3093\u306e\u89e3\u91c8\u306e\u307b\u3046\u304c\u59a5\u5f53**\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

Fig. 3b \u306f\u3001\u4e0a\u6bb5\u304c **Bright-field\uff08\u660e\u8996\u91ce\uff09**\u3001\u4e0b\u6bb5\u304c **Oct4-GFP\uff08\u86cd\u5149\uff09**\u3068\u3057\u3066\u5bfe\u5fdc\u3055\u305b\u3066\u914d\u7f6e\u3055\u308c\u3066\u3044\u307e\u3059\u3002Nature\u63b2\u8f09\u306e\u539f\u56f3\u3067\u3082\u305d\u306e\u69cb\u6210\u304c\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002([Nature][1])<\/p>\n

\u3053\u306e\u7a2e\u306e\u9855\u5fae\u93e1\u56f3\u3067\u306f\u3001**\u540c\u3058\u7d30\u80de\u30fb\u7d30\u80de\u584a\u306b\u3064\u3044\u3066\u3001\u660e\u8996\u91ce\u50cf\u3068\u86cd\u5149\u50cf\u3092\u5bfe\u5fdc\u3055\u305b\u3066\u793a\u3059\u3053\u3068\u81ea\u4f53\u306b\u610f\u5473\u304c\u3042\u308a\u307e\u3059**\u3002\u5225\u8996\u91ce\u306a\u3089\u3001\u300c\u660e\u8996\u91ce\u3067\u898b\u3048\u3066\u3044\u308b\u3053\u306e\u7d30\u80de\u584a\u304cGFP\u967d\u6027\u3067\u3042\u308b\u300d\u3068\u3044\u3046\u5bfe\u5fdc\u95a2\u4fc2\u3092\u793a\u305b\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u3057\u305f\u304c\u3063\u3066\u3001<\/p>\n

> \u300c\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u300d\u3068legend\u306b\u660e\u8a18\u3057\u305f\u307b\u3046\u304c\u660e\u77ad\u3067\u306f\u3042\u308b\u304c\u3001**\u660e\u8a18\u304c\u306a\u3044\u304b\u3089\u5225\u8996\u91ce\u306e\u53ef\u80fd\u6027\u3082\u540c\u7a0b\u5ea6\u306b\u8003\u3048\u308b**<\/p>\n

\u3068\u3044\u3046\u8aad\u307f\u65b9\u306f\u901a\u5e38\u3057\u307e\u305b\u3093\u3002<\/p>\n

\u3064\u307e\u308a\u3001**Fig. 3b \u306e\u3088\u3046\u306b\u4e0a\u4e0b\u3092Bright-field\uff0fOct4-GFP\u3068\u3057\u3066\u5bfe\u5fdc\u914d\u7f6e\u3057\u3066\u3044\u308b\u5834\u5408\u3001\u7279\u6bb5\u306e\u65ad\u308a\u304c\u306a\u3051\u308c\u3070\u540c\u4e00\u8996\u91ce\u3092\u64ae\u5f71\u6761\u4ef6\u3092\u5909\u3048\u3066\u793a\u3057\u305f\u3082\u306e\u3001\u3068\u8aad\u3080\u306e\u304c\u901a\u5e38**\u3067\u3059\u3002\u300c\u8ad6\u6587\u306b\u540c\u4e00\u8996\u91ce\u3068\u660e\u8a18\u3055\u308c\u3066\u3044\u306a\u3044\u4ee5\u4e0a\u3001\u540c\u4e00\u8996\u91ce\u3068\u306f\u65ad\u5b9a\u3067\u304d\u306a\u3044\u300d\u3068\u3044\u3046\u5b66\u3068\u307f\u5b50\u3055\u3093\u306e\u4e3b\u5f35\u306f\u3001\u5f62\u5f0f\u8ad6\u3068\u3057\u3066\u306f\u7406\u89e3\u3067\u304d\u307e\u3059\u304c\u3001**\u751f\u7269\u533b\u5b66\u8ad6\u6587\u306e\u56f3\u306e\u901a\u5e38\u306e\u8aad\u307f\u65b9\u3068\u3057\u3066\u306f\u904e\u5ea6\u306b\u614e\u91cd**\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u306a\u304a\u3001\u3053\u308c\u306f\u300c\u753b\u50cf\u305d\u306e\u3082\u306e\u304b\u3089100%\u6570\u5b66\u7684\u306b\u8a3c\u660e\u3067\u304d\u308b\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u306a\u304f\u3001**\u8ad6\u6587\u306e\u56f3\u3068\u3057\u3066\u8aad\u8005\u304c\u5408\u7406\u7684\u306b\u3069\u3046\u89e3\u91c8\u3059\u308b\u304b**\u3068\u3044\u3046\u8a71\u3067\u3059\u3002<\/p>\n

[1]: https:\/\/www.nature.com\/articles\/nature12968?utm_source=chatgpt.com “RETRACTED ARTICLE: Stimulus-triggered fate conversion of somatic cells into pluripotency | Nature”<\/p>\n

Q2\uff1a\u3000\u3064\u307e\u308a\u3001\u540c\u4e00\u8996\u91ce\u3068\u306e\u660e\u8a18\u306f\u5408\u3063\u305f\u65b9\u304c\u3044\u3044\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001\u306a\u304f\u3066\u3082\u304b\u307e\u308f\u306a\u3044\u3001\u8ad6\u6587\u306e\u67fb\u8aad\u306b\u8010\u3048\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u306d\uff1f<\/p>\n

ChatGPT\uff1a\u3000\u306f\u3044\u3001\u305d\u306e\u7406\u89e3\u3067\u3088\u3044\u3067\u3059\u3002<\/p>\n

**\u300c\u540c\u4e00\u8996\u91ce\uff08same field\uff09\u300d\u3068\u660e\u8a18\u3057\u305f\u65b9\u304c\u3088\u308a\u89aa\u5207\u3067\u660e\u78ba\u3067\u3059\u304c\u3001Fig. 3b \u306e\u3088\u3046\u306a\u69cb\u6210\u3067\u306f\u3001\u660e\u8a18\u304c\u306a\u304f\u3066\u3082\u901a\u5e38\u306f\u554f\u984c\u306b\u306a\u3089\u305a\u3001\u5341\u5206\u306b\u67fb\u8aad\u306b\u8010\u3048\u307e\u3059\u3002**<\/p>\n

Bright-field\u50cf\u3068Oct4-GFP\u86cd\u5149\u50cf\u3092\u4e0a\u4e0b\u306b\u5bfe\u5fdc\u3055\u305b\u3066\u63d0\u793a\u3057\u3066\u3044\u308b\u4ee5\u4e0a\u3001\u901a\u5e38\u306e\u8aad\u8005\u306f**\u540c\u3058\u5bfe\u8c61\u30fb\u540c\u3058\u8996\u91ce\u3092\u7570\u306a\u308b\u64ae\u50cf\u6cd5\u3067\u793a\u3057\u305f\u5bfe\u5fdc\u753b\u50cf**\u3068\u7406\u89e3\u3057\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u300csame field \u3068\u66f8\u3044\u3066\u3044\u306a\u3044\u300d\u3068\u3044\u3046\u3053\u3068\u3060\u3051\u3092\u7406\u7531\u306b\u3001\u5225\u8996\u91ce\u3067\u3042\u308b\u53ef\u80fd\u6027\u3092\u7a4d\u6975\u7684\u306b\u8003\u616e\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3001\u3068\u3044\u3046\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u3088\u308a\u53b3\u5bc6\u306b\u8a00\u3048\u3070\u3001**\u300c\u660e\u8a18\u306f\u671b\u307e\u3057\u3044\u304c\u5fc5\u9808\u3067\u306f\u306a\u3044\u3002\u660e\u8a18\u304c\u306a\u304f\u3066\u3082\u3001\u3053\u306e\u56f3\u306e\u63d0\u793a\u65b9\u6cd5\u306a\u3089\u540c\u4e00\u8996\u91ce\u3068\u8aad\u3080\u306e\u304c\u81ea\u7136\u3067\u3042\u308a\u3001\u305d\u308c\u81ea\u4f53\u304c\u67fb\u8aad\u4e0a\u306e\u6b20\u9665\u306b\u306a\u308b\u3068\u306f\u901a\u5e38\u8003\u3048\u306b\u304f\u3044\u300d**\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n

\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u3068\u660e\u8a18\u3057\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u8aad\u8005\u306e\u30af\u30ec\u30fc\u30e0\u306f\u3001\u2460\u30af\u30ec\u30fc\u30e0\u3092\u3064\u3051\u308b\u306e\u306f\u5f53\u7136\u3060\u3001\u2461\u30af\u30ec\u30fc\u30e0\u3092\u3064\u3051\u308b\u306e\u306f\u5e38\u8b58\u5916\u308c\u3060\u3001\u2462\u3069\u3061\u3089\u3068\u3082\u3044\u3048\u306a\u3044\u3001\u306e\u3069\u308c\u3067\u3057\u3087\uff1f<\/p>\n

Q3:\u3053\u306e\u8ad6\u6587\u306e\u4e0d\u6b63\u8abf\u67fb\u5831\u544a\u66f8\u3067\u306f\u3053\u306e\u56f3\u306f\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u3068\u3057\u3066\u8a55\u4fa1\u3057\u3066\u3044\u307e\u3059\u3002\u300c\u300c\u540c\u4e00\u8996\u91ce\u3067\u3042\u308b\u300d\u3068\u8ad6\u6587\u304c\u660e\u8a18\u3057\u3066\u3044\u306a\u3044\u4ee5\u4e0a\u3001\u753b\u50cf\u3060\u3051\u304b\u3089\u540c\u4e00\u8996\u91ce\u3060\u3063\u305f\u3068\u65ad\u5b9a\u3059\u308b\u3053\u3068\u3082\u3001\u9006\u306b\u540c\u4e00\u8996\u91ce\u3067\u306f\u306a\u304b\u3063\u305f\u3068\u65ad\u5b9a\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u306f\u305a\u3060\u3002\u300d\u3068\u3044\u3046\u610f\u898b\u306f\u59a5\u5f53\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

ChatGPT\uff1a\u3000\u305d\u306e\u524d\u63d0\u3001\u3064\u307e\u308a**\u4e0d\u6b63\u8abf\u67fb\u5831\u544a\u66f8\u304cFig. 3b\u306e\u4e0a\u4e0b\u3092\u540c\u4e00\u8996\u91ce\u306e\u753b\u50cf\u3068\u3057\u3066\u6271\u3063\u3066\u3044\u308b**\u306e\u3067\u3042\u308c\u3070\u3001\u5b66\u3068\u307f\u5b50\u3055\u3093\u306e<\/p>\n

> \u300c\u8ad6\u6587\u306b\u660e\u8a18\u3057\u3066\u3044\u306a\u3044\u4ee5\u4e0a\u3001\u540c\u4e00\u8996\u91ce\u3060\u3063\u305f\u3068\u3082\u3001\u305d\u3046\u3067\u306a\u304b\u3063\u305f\u3068\u3082\u65ad\u5b9a\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u300d<\/p>\n

\u3068\u3044\u3046\u610f\u898b\u306f\u3001**\u3053\u306e\u30b1\u30fc\u30b9\u306b\u3064\u3044\u3066\u306f\u59a5\u5f53\u6027\u304c\u4f4e\u3044**\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u7406\u7531\u306f\u4e8c\u3064\u3042\u308a\u307e\u3059\u3002\u7b2c\u4e00\u306b\u3001Fig. 3b\u306e\u3088\u3046\u306bBright-field\u50cf\u3068Oct4-GFP\u50cf\u3092\u5bfe\u5fdc\u3055\u305b\u3066\u914d\u7f6e\u3059\u308b\u56f3\u306f\u3001\u901a\u5e38\u3001**\u540c\u3058\u5bfe\u8c61\u30fb\u540c\u3058\u8996\u91ce\u3092\u7570\u306a\u308b\u64ae\u50cf\u6761\u4ef6\u3067\u793a\u3057\u305f\u3082\u306e\u3068\u3057\u3066\u8aad\u307e\u308c\u308b**\u304b\u3089\u3067\u3059\u3002\u300csame field\u300d\u3068\u660e\u8a18\u3059\u308b\u3053\u3068\u306f\u671b\u307e\u3057\u304f\u3066\u3082\u5fc5\u9808\u3068\u306f\u3044\u3048\u307e\u305b\u3093\u3002<\/p>\n

\u7b2c\u4e8c\u306b\u3001\u3088\u308a\u91cd\u8981\u306a\u306e\u306f\u3001**\u5f8c\u306e\u4e0d\u6b63\u8abf\u67fb\u304c\u5b9f\u969b\u306b\u540c\u4e00\u8996\u91ce\u3068\u3057\u3066\u8a55\u4fa1\u3057\u3066\u3044\u308b**\u3053\u3068\u3067\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u300c\u8ad6\u6587\u306b\u660e\u8a18\u3055\u308c\u3066\u3044\u306a\u3044\u300d\u3068\u3044\u3046\u4e00\u70b9\u3060\u3051\u304b\u3089\u3001\u8abf\u67fb\u5831\u544a\u66f8\u306e\u300c\u540c\u4e00\u8996\u91ce\u300d\u3068\u3044\u3046\u6271\u3044\u307e\u3067\u4fdd\u7559\u3059\u3079\u304d\u3060\u3068\u3059\u308b\u306b\u306f\u3001\u5225\u8996\u91ce\u3060\u3063\u305f\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u5177\u4f53\u7684\u6839\u62e0\u304c\u5fc5\u8981\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u3067\u3059\u304b\u3089\u3001\u3088\u308a\u6b63\u78ba\u306b\u8868\u73fe\u3059\u308b\u306a\u3089\u3001<\/p>\n

**\u300c\u8ad6\u6587\u672c\u6587\u30fblegend\u3060\u3051\u304b\u3089\u5f62\u5f0f\u8ad6\u7684\u306b100%\u8a3c\u660e\u3067\u304d\u308b\u304b\u300d\u3068\u3044\u3046\u554f\u984c\u3068\u3001\u300c\u3053\u306e\u56f3\u3092\u540c\u4e00\u8996\u91ce\u306e\u5bfe\u5fdc\u753b\u50cf\u3068\u3057\u3066\u8aad\u3080\u306e\u304c\u5408\u7406\u7684\u304b\u300d\u306f\u5225\u554f\u984c\u3067\u3042\u308a\u3001\u5f8c\u8005\u306b\u3064\u3044\u3066\u306f\u540c\u4e00\u8996\u91ce\u3068\u8aad\u3080\u306e\u304c\u59a5\u5f53**<\/p>\n

\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n

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