{"id":25989,"date":"2024-12-06T15:53:31","date_gmt":"2024-12-06T06:53:31","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=25989"},"modified":"2024-12-19T04:39:31","modified_gmt":"2024-12-18T19:39:31","slug":"%e8%8b%b1%e6%96%87%e7%a7%91%e5%ad%a6%e8%ab%96%e6%96%87%e3%81%ae%e8%a8%98%e8%bf%b0%e3%81%af%e6%96%87%e6%b3%95%e9%80%9a%e3%82%8a%e8%aa%ad%e3%82%93%e3%81%a7%e3%81%af%e3%81%84%e3%81%91%e3%81%aa%e3%81%84","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=25989","title":{"rendered":"\u82f1\u6587\u79d1\u5b66\u8ad6\u6587\u306e\u8a18\u8ff0\u306f\u6587\u6cd5\u901a\u308a\u8aad\u3093\u3067\u306f\u3044\u3051\u306a\u3044"},"content":{"rendered":"

STAP\u8ad6\u6587Article\u306eMETHODS\u306b\u3042\u308b\u30ad\u30e1\u30e9\u4f5c\u6210\u306e\u305f\u3081\u306eSTAP\u7d30\u80de\u584a\u306b\u3064\u3044\u3066\u306e\u82f1\u6587\u306b\u3064\u3044\u3066\u3001\u5b66\u3068\u307f\u5b50\u3068\u5f53\u65b9\u7b49\u3067\u89e3\u91c8\u304c\u7570\u306a\u308b\u3068\u3044\u3046\u306e\u304c\u524d\u8a18\u4e8b\u306e\u30b3\u30e1\u30f3\u30c8\u3067\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002\u524d\u8a18\u4e8b\u306e\u30b3\u30e1\u30f3\u30c8\u6570\u304c100\u4ef6\u306b\u8fd1\u3065\u3044\u305f\u306e\u3067\u65b0\u3057\u3044\u8a18\u4e8b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u306f\u3001\u8ad6\u6587\u82f1\u8a9e\u306f\u6587\u6cd5\u901a\u308a\u7406\u89e3\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u3001\u8ad6\u6587\u5168\u4f53\u3092\u7406\u89e3\u3057\u3066\u3053\u308c\u306b\u77db\u76fe\u3057\u306a\u3044\u3088\u3046\u306b\u89e3\u91c8\u3057\u306a\u3044\u3068\u3044\u3051\u306a\u3044\u3068\u4e3b\u5f35\u3059\u308b\u306e\u3067\u3059\u3002\u6587\u6cd5\u901a\u308a\u8aad\u3093\u3067\u7406\u89e3\u3057\u3066\u8ad6\u6587\u3092\u8aad\u3080\u3068\u3044\u3046\u306e\u304c\u666e\u901a\u3067\u3001\u8ad6\u6587\u5185\u306b\u6587\u6cd5\u901a\u308a\u306e\u89e3\u91c8\u3092\u3059\u308b\u3068\u77db\u76fe\u3059\u308b\u3053\u3068\u304c\u3042\u3063\u305f\u3089\uff08\u666e\u901a\u306f\u306a\u3044\u3067\u3059\uff09\u3001\u305d\u306e\u3088\u3046\u306a\u8ad6\u6587\u306f\u68c4\u5374\u3059\u3079\u304d\uff08\u3042\u308b\u3044\u306f\u6587\u6cd5\u901a\u308a\u306b\u89e3\u91c8\u3067\u304d\u306a\u3044\u304b\u3089\uff09\u306a\u3093\u3067\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u306f\u3001\u77db\u76fe\u3057\u3066\u3044\u305f\u3089\u3001\u305d\u306e\u4e00\u65b9\u3092\u6587\u6cd5\u901a\u308a\u89e3\u91c8\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u3068\u8a00\u3046\u306e\u3067\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u306f\u3001\u79d1\u5b66\u8ad6\u6587\u306e\u82f1\u6587\u306f\u6587\u6cd5\u901a\u308a\u306b\u89e3\u91c8\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u300c\u6587\u7ae0\u306e\u89e3\u91c8\u306b\u304a\u3044\u3066\u306f\u3001\u5b9f\u9a13\u7d50\u679c\u306e\u5168\u4f53\u50cf\u3092\u57fa\u306b\u5224\u65ad\u3059\u308b\u3053\u3068\u304c\u6700\u512a\u5148\u3055\u308c\u307e\u3059\u3002\u300d<\/span><\/a>\u3068\u3044\u3046\u5b66\u3068\u307f\u5b50AI\u306e\u56de\u7b54\u7d50\u679c\u3092\u6b63\u3057\u3044\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u3082\u3063\u3068\u3082\u3053\u306e\u56de\u7b54\u306f\u5b66\u3068\u307f\u5b50\u304c\u8a00\u308f\u305b\u305f\u3082\u306e\u3067\u3059\u304b\u3089\u3001\u5b66\u3068\u307f\u5b50\u306e\u4e3b\u5f35\u3067\u3059\u3002<\/p>\n

\u300cmost<\/strong> day-7 clusters that were large and contained more than a few dozen small cells were positive for Oct4.\u300d\u3068\u3044\u3046\u306e\u304c\u554f\u984c\u306e\u82f1\u6587\u3067\u3059\u3002<\/p>\n

most\u304cday-7\u306b\u304b\u304b\u308b\u306e\u304bclusters\u306b\u304b\u304b\u308b\u306e\u304b\u3068\u3044\u3046\u554f\u984c\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u306e\u89e3\u91c8\u306f\u3001\u672c\u6587\uff08METHODS\u4ee5\u5916\u306e\u90e8\u5206\uff09\u306e\u8a18\u8ff0\u306b\u5f93\u3046\u3068\u30ad\u30e1\u30e9\u4f5c\u6210\u306e\u305f\u3081\u306e\u57f9\u990a\u671f\u9593\u306f\uff17\u65e5\u9593\u3068\u9650\u5b9a\u3055\u308c\u3066\u3044\u306a\u3044\u3001day-6\u3082day-8\u3082\u3042\u308b\u304b\u3089\u3001\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u306f\uff17\u65e5\u9593\u57f9\u990aday-7\u3067\u3042\u308b\u3068\u89e3\u91c8\u3059\u3079\u304d\u3001\u3064\u307e\u308amost \u306fday-7\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u306e\u3067\u3059\u3002\u672c\u6587\u306e\u3069\u306e\u8a18\u8ff0\u304c\u8a72\u5f53\u3059\u308b\u306e\u304b\u3068\u805e\u3044\u3066\u3082\u7b54\u3048\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u5f53\u65b9\u7b49\u306fclusters\u306b\u304b\u304b\u308b\u3001\u3064\u307e\u308a\u300c\u307b\u3068\u3093\u3069\u306e\u7d30\u80de\u584a\u300d\u3068\u89e3\u91c8\u3059\u308b\u306e\u304c\u6b63\u3057\u3044\u3068\u4e3b\u5f35\u3057\u3001\u3053\u306e\u8a18\u8ff0\u304c\u672c\u6587\u306e\u3044\u304b\u306a\u308b\u8a18\u8ff0\u3068\u3082\u77db\u76fe\u304c\u306a\u3044\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u30ad\u30e1\u30e9\u4f5c\u6210\u306e\u5834\u5408\u3001\u57f9\u990a\u671f\u9593\u304c\uff17\u65e5\u9593\u304c\u6700\u9069\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3059\u5b9f\u9a13\u3092\u9664\u3044\u3066\u3001day-6\u3082day-8\u3082\u3042\u308b\u3068\u306f\u672c\u6587\u306b\u66f8\u3044\u3066\u306a\u3044\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u300c\u4e00\u822c\u7684\u306b\u306f\u3001most \u306f\u3001\u30af\u30e9\u30b9\u30bf\u30fc\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u8aad\u307f\u65b9\u304c\u666e\u901a\u3067\u3042\u308a\u3001AI\u306f\u305d\u3046\u8a00\u3044\u307e\u3059\u3002\u300d<\/span>\u3068\u8a00\u3044\u307e\u3059\u304c\u3053\u3053\uff08STAP\u8ad6\u6587\u3067\u306f\uff09\u3061\u304c\u3046\u3068\u8a00\u3046\u306e\u3067\u3059\u3002
\n\u30fb\u300c\u3057\u304b\u3057\u3001most \u304c day-7 \u306b\u304b\u304b\u308b\u3068\u7406\u89e3\u3059\u308b\u3068\u3001STAP\u8ad6\u6587\u306b\u66f8\u304b\u308c\u305f\u5185\u5bb9\u304c\u53cd\u6620\u3067\u304d\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000\u300cSTAP\u8ad6\u6587\u306b\u66f8\u304b\u308c\u305f\u5185\u5bb9\u300d<\/span>\u304c\u4f55\u306a\u306e\u304b\u308f\u304b\u3089\u306a\u3044\u306e\u3067\u610f\u5473\u4e0d\u660e\u3067\u3059\u3002
\n\u30fb\u300c\u305d\u3053\u3092\u3001AI\u306b\u6559\u3048\u308b\u3068\u3001\u305d\u306e\u5834\u5408\u306f\u3001most \u304c day-7 \u306b\u304b\u304b\u308b\u8aad\u307f\u65b9\u3082\u3067\u304d\u308b\u300d<\/span>\u3000\u2190\u3000\u504f\u898b\u3001\u5618\u3092\u6dfb\u3048\u308b\u3068\u3053\u308c\u306b\u6cbf\u3063\u3066\u56de\u7b54\u3055\u308c\u308b\u306e\u3067\u3059\u304b\u3089\u3001\u300c\u305d\u3053\u300d<\/span>\u304c\u4f55\u306a\u306e\u304b\u5b66\u3068\u307f\u5b50\u304c\u63d0\u793a\u3057\u306a\u3044\u3068\u610f\u5473\u306e\u306a\u3044\u6587\u7ae0\u306b\u306a\u308a\u307e\u3059\u3002
\n\u30fb\u300cday-7 \u306e\u9178\u6d74\u7d30\u80de\u307b\u3068\u3093\u3069\u304c\u3001\u4e00\u90e8\u5c0f\u7d30\u80de\u304c\u5149\u3063\u3066\u5927\u304d\u304f\u51dd\u96c6\u3057\u3066\u3044\u308b\u72b6\u614b\u306b\u306a\u3063\u3066\u308b\u3068\u306e\u89e3\u91c8\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3060\u304b\u3089\u3001most\u306f\u30af\u30e9\u30b9\u30bf\u30fc\u306b\u304b\u304b\u308b\u8a9e\u53e5\u3067\u306a\u3044\u300d<\/span>\u3000\u2190\u3000\u300c\u9178\u6d74\u7d30\u80de\u307b\u3068\u3093\u3069\u304c\u3001\u5927\u304d\u304f\u51dd\u96c6\u3057\u3066\u3044\u308b\u72b6\u614b\u306b\u306a\u3063\u3066\u308b\u300d<\/span>\u3068\u306f\u5b66\u3068\u307f\u5b50\u3092\u542b\u3081\u3060\u308c\u3082\u89e3\u91c8\u3057\u3066\u3044\u307e\u305b\u3093\u306e\u3067\u7121\u610f\u5473\u306a\u6587\u7ae0\u3067\u3059\u3002\u300c\u3060\u304b\u3089\u300d\u306e\u524d\u306e\u6587\u304c\u610f\u5473\u4e0d\u660e\u3067\u3059\u3002
\n\u30fb\u300c\u5c0f\u3055\u306a\u7d30\u80de\u304c\u5149\u308a\u3001\u305d\u306e\u5c0f\u7d30\u80de\u3092\u542b\u3080\u7d30\u80de\u96c6\u56e3\u304c\u51dd\u96c6\u3059\u308b\u304b\u3089\u30af\u30e9\u30b9\u30bf\u30fc\u3082\u5149\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001 day-7\u7d30\u80de\u304c\u3001\u307b\u3068\u3093\u3069\u304c\u305d\u3046\u3057\u305f\u7d30\u80de\u72b6\u614b\u306b\u306a\u308b\u3068\u306f\u3001STAP\u8ad6\u6587\u306b\u306f\u66f8\u304b\u308c\u3066\u3044\u306a\u3044\u3002\u300d<\/span>\u3000\u2190\u3000\u300cday-7\u7d30\u80de\u306e\u307b\u3068\u3093\u3069\u304c\u5149\u308b\u7d30\u80de\u72b6\u614b\u306b\u306a\u308b\u300d<\/span>\u3068\u306f\u5f53\u65b9\u306f\u767a\u8a00\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u304a\u9580\u9055\u3044\u306e\u53cd\u8ad6\u3067\u3059\u3002\u7d30\u80de\u304c\u96c6\u56e3\u3068\u306a\u3063\u305f\u306e\u304c\u51dd\u96c6\u584a\u3067\u3059\u304b\u3089\u300c\u7d30\u80de\u96c6\u56e3\u304c\u51dd\u96c6\u3059\u308b\u300d<\/span>\u306f\u91cd\u8a00\u3067\u3059\u3002
\n\u30fb\u300c\u3053\u3046\u3057\u305f\u3053\u3068\u3092AI\u306b\u3001\u6559\u3048\u308b\u3068\u3001AI\u306f\u3001most \u304c day-7 \u306b\u304b\u304b\u308b\u3068\u306e\u7406\u89e3\u3082\u3042\u308b\u3068\u3001AI\u306f\u89e3\u7b54\u3057\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u7e70\u308a\u8fd4\u3057\u307e\u3059\u304c\u300c\u3053\u3046\u3057\u305f\u3053\u3068\u300d<\/span>\u3068\u306f\u4f55\u306a\u306e\u304b\u3001\u8cea\u554f\u306b\u4f55\u3068\u6dfb\u3048\u305f\u306e\u304b\u3092\u958b\u793a\u3057\u3066\u3044\u306a\u3044\u306e\u3067\u610f\u5473\u306e\u306a\u3044\u6587\u7ae0\u3067\u3059\u3002
\n\u30fb\u300c\u305f\u3081\u606f\u3055\u3093\u306f\u3001\u300c\u307b\u3069\u3093\u3069\u306e\u5927\u304d\u306aday-7\u7d30\u80de\u584a\u306fOct4\u967d\u6027\u3067\u3042\u308b\u300d\u3068\u7ffb\u8a33\u3059\u308b\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u300cday-7\u306e\u5927\u304d\u306a\u7d30\u80de\u584a\u306e\u307b\u3068\u3093\u3069\u304cOct4\u967d\u6027\u3067\u3042\u308b\u300d\u3068\u8a00\u3063\u3066\u3044\u307e\u3059\u3002\u300c\u307b\u3069\u3093\u3069\u306e\u5927\u304d\u306aday-7\u7d30\u80de\u584a\u300d\u3068\u3059\u308b\u3068\u300c\u307b\u3068\u3093\u3069\u300d\u304c\u3069\u3053\u306b\u304b\u304b\u308b\u306e\u304b\u66d6\u6627\u306b\u306a\u308a\u307e\u3059\u3002\u5f53\u65b9\u3089\u306e\u767a\u8a00\u3092\u6b63\u78ba\u306b\u5f15\u7528\u3057\u3066\u304f\u3060\u3055\u3044\uff08oTake\u3055\u3093\uff1a\u300c7\u65e5\u76ee\u306e\u30af\u30e9\u30b9\u30bf\u30fc\u306e\u307b\u3068\u3093\u3069\u304cOct4\u967d\u6027\u300d<\/span><\/a>\u3001\u305f\u3081\u606f\uff1a\u300cday 7\u306e\u7d30\u80de\u584a\u306e\u307b\u3068\u3093\u3069\uff08\u591a\u304f\u3001\u5927\u90e8\u5206\uff09\u306fOct\uff14\u967d\u6027\u300d<\/span><\/a>\uff09\u3002
\n\u30fb\u300c\u8ad6\u6587\u3067\u306f\u3001day-7\u306b\u3001\u5149\u308b\u5c0f\u7d30\u80de\u3092\u542b\u3080\u5927\u578b\u51dd\u96c6\u5f62\u72b6\u306e\u7d30\u80de\u96c6\u56e3\u304c\u3067\u3066\u304f\u308b\u304b\u3089\u3001\u305d\u308c\u3092\u5b9f\u9a13\u8005\u304c\u9078\u3093\u3060\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u554f\u984c\u306eMETHODS\u306b\u66f8\u3044\u3066\u3042\u308b\u306e\u306f\u300c\u5927\u304d\u306a\u7d30\u80de\u96c6\u56e3\u306e\u307b\u3068\u3093\u3069\u304cOct4\u967d\u6027\u3067\u3053\u308c\u3092\u30ad\u30e1\u30e9\u4f5c\u6210\u306b\u4f7f\u3063\u305f\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u3001\u5b66\u3068\u307f\u5b50\u3082\u3053\u306e\u3088\u3046\u306b\u89e3\u91c8\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u304b\uff1f
\n\u30fb\u300cday-7\u7d30\u80de\u304c\u305d\u3046\u3057\u305f\u72b6\u614b\u306e\u307f\u3067\u306a\u3044\u3053\u3068\u306f\u3001STAP\u8ad6\u6587\u304b\u3089\u8aad\u307f\u53d6\u308b\u3053\u3068\u306a\u3093\u3067\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u305d\u3046\u3067\u3059\u3002\u5c0f\u3055\u3044\u7d30\u80de\u584a\u3082\u3001\u5149\u3089\u306a\u3044\u7d30\u80de\u584a\u3082\u3042\u308b\u3068\u3001METHODS\u306e\u3053\u306e\u8a18\u8f09\u304b\u3089\u8aad\u307f\u53d6\u308c\u307e\u3059\u304c\u3001most \u304cday-7\u306b\u304b\u304b\u308b\u3053\u3068\u3092\u80af\u5b9a\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002
\n\u30fb\u300c\u305f\u3081\u606f\u3055\u3093\u306f\u3001\u66f8\u3044\u3066\u3082\u7121\u3044\u3053\u3068\u3092\u3001\u52dd\u624b\u306b\u8a2d\u5b9a\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u5f53\u65b9\u306e\u767a\u8a00\u306e\u3069\u3053\u304c\u300c\u66f8\u3044\u3066\u3082\u7121\u3044\u3053\u3068\u300d<\/span>\u306a\u3093\u3067\u3057\u3087\u3046\u304b\uff1f\u8a00\u3063\u3066\u3082\u3089\u304a\u3046\u3058\u3083\u306a\u3044\u3067\u3059\u304b\u3002\u5618\u3092\u66f8\u304f\u306a\u3002
\n\u30fb\u300c\u4ee5\u4e0b\u306e\u305f\u3081\u606f\u6587\u7ae0\u3082\u3001\u8ad6\u6587\u306b\u66f8\u304b\u308c\u3066\u3044\u306a\u3044\u4e8b\u3092\u66f8\u3044\u3066\u3044\u307e\u3059\u3002\u5927\u304d\u306a\u7d30\u80de\u584a\u3067\u3082\u5149\u3089\u306a\u3044\u3082\u306e\u304c\u5c11\u6570\u3042\u308b\u3068\u306f\u8ad6\u6587\u306b\u306f\u66f8\u3044\u3066\u3044\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000\u300c\u5927\u304d\u306a\u7d30\u80de\u584a\u306e\u307b\u3068\u3093\u3069<\/strong>\u304cOct4\u967d\u6027\uff08\u5149\u308b\uff09\u300d\u3068\u66f8\u3044\u3066\u3042\u308b\u306e\u3067\u3059\u304b\u3089\u300c\u5149\u3089\u306a\u3044\u3082\u306e\u304c\u5c11\u6570\u3042\u308b\u300d<\/span>\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u65e5\u672c\u8a9e\u308f\u304b\u3089\u306a\u3044\u306e\uff1f
\n\u30fb\u300c\u305f\u3081\u606f\u3055\u3093\u306b\u306f\u7406\u89e3\u3067\u304d\u3066\u3044\u307e\u305b\u3093\u3002\u305f\u3081\u606f\u3055\u3093\u306f\u3001\u5149\u308b\u7d30\u80de\u306f\u5c0f\u3055\u3044\u3068\u3044\u3046\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000STAP\u7d30\u80de\u306f\u5c0f\u3055\u3044\u3001STAP\u7d30\u80de\u306fOct4\u30fcGFP\u3092\u767a\u73fe\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u306e\u304c\u8ad6\u6587\u306e\u4e3b\u65e8\u3067\u3059\u304b\u3089\u3001\u5149\u308b\u7d30\u80de\u306f\u5c0f\u3055\u3044\u3068\u3044\u3046\u3053\u3068\u306a\u3093\u3067\u3057\u3087\u3046\u306d\u3002\u8ad6\u6587\u306e\u4e3b\u5f35\u306f\u7406\u89e3\u3067\u304d\u3066\u307e\u3059\u3002\u3057\u304b\u3057\u3053\u306e\u5149\u306f\u6b7b\u306b\u884c\u304f\u7d30\u80de\u306e\u7121\u79e9\u5e8f\u306a\u86cd\u5149\u3060\u3063\u305f\u308f\u3051\u3067\u3059\u306d\u3002
\n\u30fb\u300c\u5c0f\u3055\u306a\u7d30\u80de\u584a\u306a\u3093\u3066\u306e\u8a71\u306f\u4f55\u3082\u51fa\u3066\u304d\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000\u5927\u304d\u306a\u7d30\u80de\u584a\u304c\u3042\u308b\u306e\u3067\u3059\u304b\u3089\u5c0f\u3055\u306a\u7d30\u80de\u584a\u3082\u3042\u3063\u305f\u3068\u3059\u308b\u306e\u304c\u5f53\u7136\u3067\u3059\u3002\u5747\u4e00\u306a\u5927\u304d\u3055\u306a\u3089\u5927\u304d\u306a\/\u5c0f\u3055\u306a\u7d30\u80de\u584a\u306a\u3069\u3068\u3044\u3044\u307e\u305b\u3093\u3002METHODS\u306b\u306f\u300cclusteres that were large\u300d\u3068\u5927\u304d\u306a\u7d30\u80de\u584a\u3068\u3042\u308b\u304b\u3089\u3001\u5c0f\u3055\u306a\u7d30\u80de\u584a\u3082\u3042\u3063\u305f\u306e\u3067\u3059\u3002
\n\u30fb\u300cmost \u3092\u3001day-7 clusters\u306b\u304b\u304b\u308b\u3068\u89e3\u91c8\u3059\u308b\u3068\u3001\u5c0f\u3055\u306a\u5149\u308b\u5c0f\u7d30\u80de\u3092\u542b\u3080\u5927\u304d\u306a\u51dd\u96c6\u584a\u304c\u51fa\u73fe\u3059\u308b\u306e\u610f\u5473\u3067\u3059\u304c\u3001\u3053\u306e\u89e3\u91c8\u3067\u306f\u3001day-7 clusters\u306f\u3001most clusters\u304c\u3001\u3053\u306e\u72b6\u614b\u306b\u306a\u308b\u3068\u3044\u3046\u610f\u5473\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u3001STAP\u8ad6\u6587\u3068\u5408\u81f4\u3057\u306a\u3044\uff08\u5b66\u3068\u307f\u5b50\u8ad6\uff09\u3068\u306a\u308a\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000METHODS\u306e\u8a18\u8ff0\u3068\u5408\u81f4\u3057\u306a\u3044\u6587\u7ae0\u306f\u8ad6\u6587\u306e\u3069\u3053\u306b\u3042\u308b\u306e\u304b\u3092\u660e\u793a\u3057\u306a\u3044\u306e\u3067\u3001\u5b66\u3068\u307f\u5b50\u306e\u4e00\u65b9\u7684\u306a\u4e3b\u5f35\u3068\u3067\u3057\u304b\u8a00\u3048\u307e\u305b\u3093\u3002most\u304cday-7\u3068clusters \u306e\u3069\u3061\u3089\u306b\u304b\u304b\u308b\u304b\u3068\u3044\u3046\u8b70\u8ad6\u306a\u306e\u3067\u3059\u304b\u3089\u300cmost \u3092\u3001day-7 clusters\u306b\u304b\u304b\u308b<\/span>\u3068\u66f8\u304f\u3068\u306a\u306b\u304c\u306a\u3093\u3060\u304b\u308f\u304b\u3089\u306a\u304f\u306a\u308a\u307e\u3059\u3002\u5c0f\u3055\u306a\u5149\u308b\u5c0f\u7d30\u80de\u3092\u542b\u3080\u5927\u304d\u306a\u51dd\u96c6\u584a\u304c\u51fa\u73fe\u3059\u308b<\/span>\u306e\u306f\u5f7c\u3089\u306e\u89b3\u5bdf\u7d50\u679c\u3067\u8ad6\u6587\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3067\u3059\u3002
\n\u30fb\u300c\u8ad6\u6587\u306b\u3042\u308b\u306e\u306f\u3001\u5149\u308b\u5c0f\u7d30\u80de\u3092\u542b\u3080\u5927\u304d\u306a\u7d30\u80de\u584a\u306e\u5b58\u5728\u3060\u3051\u3067\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u9055\u3044\u307e\u3059\u3002\u8ad6\u6587\u3067\u4f7f\u3063\u305f\u306e\u306f\u5927\u304d\u306a\u7d30\u80de\u584a\u3067\u3001\u300c\u5149\u7d30\u80de\u584a\u306e\u5b58\u5728\u3060\u3051\u300d<\/span>\u3092\u66f8\u3044\u3066\u3044\u308b\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u8ad6\u6587\u3092\u6b63\u3057\u304f\u7406\u89e3\u3057\u3066\u6b63\u3057\u3044\u65e5\u672c\u8a9e\u3067\u8868\u73fe\u3057\u306a\u3055\u3044\u3002
\n\u30fb\u300c\u305f\u3081\u606f\u89e3\u91c8\u306e\u300c\u5c0f\u3055\u306a\u7d30\u80de\u304b\u3089\u306a\u308b\u5927\u304d\u306a\u51dd\u96c6\u584a\u300d\u3082\u3001\u884c\u304d\u904e\u304e\u89e3\u91c8\u3067\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u7d30\u80de\u584a\u306b\u5927\u304d\u306a\u7d30\u80de\u304c\u3042\u308b\/\u306a\u3044\u306f\u8ad6\u6587\u306b\u306f\u8a18\u8f09\u3055\u308c\u3066\u307e\u305b\u3093\u304c\u3001\u5927\u304d\u306a\u7d30\u80de\u306fSTAP\u7d30\u80de\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u304b\u3089\u7d30\u80de\u584a\u306b\u306f\u542b\u307e\u308c\u3066\u306a\u3044\u3068\u8457\u8005\u7b49\u306f\u3057\u305f\u3044\u306e\u3067\u306f\uff1f\u5b9f\u969b\u306b\u306f\u5927\u304d\u306a\u7d30\u80de\uff1dES\u7d30\u80de\u304c\u3042\u3063\u305f\u3093\u3067\u3059\u3051\u3069\u306d\u3002
\n\u30fb\u300c\u305d\u3053\u306b\u5149\u308b\u5c0f\u7d30\u80de\u304c\u304b\u306a\u308a\u3042\u308b\u3068\u3044\u3046\u610f\u5473\u306b\u306a\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001day-7 clusters\u306f\u3001\u3053\u308c\u3070\u3063\u304b\u308a\u306e\u7d30\u80de\u584a\u3067\u3042\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u73fe\u8c61\u306f\u3001STAP\u8ad6\u6587\u306b\u306f\u66f8\u304b\u308c\u3066\u3044\u306a\u3044\u3067\u3057\u3087\u3046\uff1f\u300d<\/span>\u3000\u2190\u3000\u3044\u308d\u3044\u308d\u306a\u5927\u304d\u3055\u3067\u5149\u3089\u306a\u3044\u7d30\u80de\u584a\u3082\u3042\u3063\u305f\u3068\u300c\u3053\u308c\u3070\u3063\u304b\u308a\u306e\u7d30\u80de\u584a\u300d<\/span>\u3067\u306f\u306a\u3044\u3068\u8ad6\u6587\u306b\u306f\u66f8\u3044\u3066\u3042\u308a\u307e\u3059\u3002
\n\u30fb\u300cmost \u3092\u3001day-7 clusters\u306b\u304b\u304b\u308b\u3068\u89e3\u91c8\u3059\u308b\u3068\u3001day-7 clusters\u306f\u3001most\u304c\u3001\u5149\u308b\u5c0f\u7d30\u80de\u304c\u304b\u306a\u308a\u3042\u308b\u7d30\u80de\u96c6\u56e3\u3068\u610f\u5473\u306b\u306a\u3063\u3066\u3057\u307e\u3044\u3001STAP\u8ad6\u6587\u3068\u5408\u81f4\u3057\u306a\u3044\u300d<\/span>\u3000\u2190\u3000\u524d\u306b\u3082\u66f8\u304d\u307e\u3057\u305f\u304cmost\u304cday-7\u306b\u304b\u304b\u308b\u306e\u304bclusters\u306b\u304b\u304b\u308b\u306e\u304b\u304c\u554f\u984c\u306a\u3093\u3067\u3059\u304b\u3089\u3001\u3053\u306e\u3088\u3046\u306b\u300cday-7 clusters\u306b\u304b\u304b\u308b\u300d<\/span>\u3068\u3044\u308f\u308c\u308b\u3068\u3001\u30ca\u30f3\u30b8\u30e3\u30e9\u30db\u30a4\u3068\u306a\u3063\u3066\u610f\u5473\u4e0d\u660e\u306b\u306a\u308a\u307e\u3059\u3002\u6b63\u3057\u3044\u65e5\u672c\u8a9e\u306e\u8868\u73fe\u304c\u3067\u304d\u308b\u3088\u3046\u52c9\u5f37\u3057\u76f4\u3057\u306a\u3055\u3044\u3002\u300cSTAP\u8ad6\u6587\u3068\u5408\u81f4\u3057\u306a\u3044\u300d<\/span>\u3068\u306f\u306a\u3093\u3067\u3059\u304b\uff1f\u300cMETHODS\u4ee5\u5916\u306e\u8a18\u8f09\u3068\u5408\u81f4\u3057\u306a\u3044\u300d\u306e\u610f\u5473\u306a\u3089\u3001\u305d\u306e\u3046\u3088\u3046\u306a\u3000METHODS\u306e\u8a18\u8ff0\u3068\u4e00\u81f4\u3057\u306a\u3044\u3068\u3044\u3046\u6587\u7ae0\u306f\u3069\u3053\u306b\u3042\u308b\u306e\u3067\u3059\u304b\uff1f\u5b66\u3068\u307f\u5b50\u3060\u3051\u304c\u5408\u81f4\u3057\u306a\u3044\u3068\u3057\u3066\u3044\u308b\u306e\u3067\u306f\uff1f
\n\u30fb\u300c\u3060\u304b\u3089\u3001\u6587\u6cd5\u7684\u306b\u3084\u3084\u5916\u308c\u308b\u3082\u306e\u306e\u3001most \u306fday-7\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u89e3\u91c8\u304c\u51fa\u3066\u304f\u308b\u300d<\/span>\u3000\u2190\u3000\u524d\u306e\u6587\u7ae0\u304c\u610f\u5473\u4e0d\u660e\uff08most \u306fday-7 clusters\u306b\u304b\u304b\u308b\uff09\u306a\u306e\u3067\u300c\u3060\u304b\u3089\u300d<\/span>\u3068\u3044\u308f\u308c\u3066\u3082\u8ad6\u7406\u304c\u6210\u7acb\u3057\u307e\u305b\u3093\u3002
\n\u30fb\u300c\u5b66\u3068\u307f\u5b50\u306eAI\u3082\u305d\u308c\u3067\u3088\u3044\u3068\u8a00\u3063\u3066\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u5b66\u3068\u307f\u5b50\u306e\u8cea\u554f\u3092\u516c\u958b\u3057\u3066\u306a\u3044\u306e\u3060\u304b\u3089\u3001\u5b66\u3068\u307f\u5b50\u306e\u504f\u898b\u3068\u5984\u60f3\u3068\u5618\u3092\u6dfb\u3048\u305f\u8cea\u554f\u3060\u304b\u3089AI\u306f\u305d\u308c\u306b\u6cbf\u3063\u3066\u300c\u3088\u3044\u300d<\/span>\u3068\u3044\u3063\u305f\u3068\u3055\u308c\u3066\u3082\u3057\u3087\u3046\u304c\u306a\u3044\u3067\u3059\u3002
\n\u30fb\u300c\u305f\u3081\u606f\u3055\u3093\u304c\u3001\u305d\u3061\u3089\u306eAI\u3078\u3001STAP\u8ad6\u6587\u306e\u5b9f\u9a13\u7d50\u679c\u3092\u6b63\u3057\u304f\u5165\u529b\u3059\u308c\u3070\u3001AI\u306f\u3001most \u306fday-7\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u89e3\u91c8\u304c\u51fa\u3066\u304f\u308b\u3068\u8a8d\u3081\u308b\u3068\u601d\u3046\u3088\u3002\u300d<\/span>\u3000\u2190\u3000\u5b9f\u9a13\u7d50\u679c\uff08Fig.1\u3068\u304bExtended Fig.1\u7b49\uff09\u306b\u306f\u5927\u304d\u306a\u7d30\u80de\u584a\u306e\u307b\u3068\u3093\u3069\u304cOct4\u967d\u6027\u3067\u3042\u3063\u305f\u3068\u3044\u3046METHODS\u306e\u8a18\u8f09\u3068\u77db\u76fe\u3059\u308b\u3088\u3046\u306a\u3053\u3068\u304c\u66f8\u3044\u3066\u306a\u3044\u304b\u3089\u300cmost \u306fday-7\u306b\u304b\u304b\u308b\u300d<\/span>\u3068\u3044\u3046AI\u306e\u56de\u7b54\u306f\u51fa\u529b\u3055\u308c\u306a\u3044\u3067\u3057\u3087\u3046\u3002\u5f53\u65b9\u306f\u77db\u76fe\u3057\u3066\u3044\u306a\u3044\u3068\u3057\u3066\u3044\u308b\u304b\u3089\u77db\u76fe\u304c\u6dfb\u3048\u3066\u3042\u308b\u8cea\u554f\u306f\u3067\u304d\u307e\u305b\u3093
\n\u30fb\u300c\u300cSTAP\u8ad6\u6587\u306e\u5143\u82f1\u6587\u3092\u5909\u66f4\u3059\u308b\u3053\u3068\u306a\u304f\u3001\u65e5\u672c\u8a9e\u89e3\u91c8\u3092\u304a\u9858\u3044\u3057\u307e\u3059\u300d\u3068AI\u306b\u983c\u3093\u3067\u304b\u3089\u3001AI\u56de\u7b54\u3092\u5f85\u3064\u306e\u304c\u826f\u3044\u3067\u3057\u3087\u3046\u3002\u300d<\/span>\u3000\u2190\u3000\u306f\u3044\u3001\u3068\u3063\u304f\u306b\u5f53\u65b9\u306e\u610f\u898b\u3092\u6dfb\u3048\u308b\u3053\u3068\u306a\u304f\u82f1\u6587\u306e\u89e3\u91c8\u3092\u805e\u304f\u3068\u3044\u3046\u3053\u3068\u3092\u5b9f\u65bd\u3057\u3066\u3044\u3066\u3001\u305d\u306e\u56de\u7b54\u306f\u300cmost \u306f clusters\u300d\u306b\u304b\u304b\u308b\u3068\u3044\u3046\u7d50\u8ad6\u3067\u3059\u3002
\n\u30fb\u300c\u300c\u3053\u306e\u7d30\u80de\u584a\u306e\u5927\u304d\u306a\u3082\u306e\u306e\u307b\u3068\u3093\u3069\uff08most\uff09\u306f\u7a0b\u5ea6\u306b\u306f\u5dee\u304c\u3042\u308b\u304c\u7dd1\u306b\u5149\u308b\u300d\u306e\u6587\u7ae0\u3067\u306f\u3001\u5927\u304d\u304f\u306a\u308b\u3068\u5149\u308b\u3044\u3046\u8aa4\u89e3\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u300d<\/span>\u3000\u2190\u3000\u5f53\u65b9\u306e\u8a33\u306b\u300c\u5927\u304d\u304f\u306a\u308b\u3068\u5149\u308b\u300d<\/span>\u3068\u3044\u3046\u610f\u5473\u306f\u898b\u51fa\u3055\u308c\u307e\u305b\u3093\u3002\u8a9e\u89e3\u3055\u308c\u307e\u305b\u3093\u3002
\n\u30fb\u300c\u521d\u671f\u5316\u7d30\u80de\u3092\u542b\u3080\u7d30\u80de\u96c6\u56e3\u306f\u3001\u51dd\u96c6\u304c\u5f37\u304f\u306a\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5149\u308b\u5c0f\u7d30\u80de\u3092\u304b\u306a\u308a\u542b\u307f\u307e\u3059\u304b\u3089\u3001\u5149\u308b\u30af\u30e9\u30b9\u30bf\u30fc\u3068\u306a\u308a\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u9178\u6d74\u3057\u305f\u304b\u3089\u51dd\u96c6\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u306f\u306a\u3044\u306e\u304c\u4e39\u7fbd\u6c0f\u306e\u30ec\u30dd\u30fc\u30c8\u3067\u300cOccasional formation of aggregates was also observed in the culture of non-treated cells, suggesting that low-pH treatment does not enhance the formation of cell aggregates.\u300d<\/a>\u3068\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3067\u3059\u304b\u3089\u521d\u671f\u5316\u3057\u305f\u3042\u308b\u3044\u306f\u5149\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u304b\u3089\u51dd\u96c6\u3057\u305f\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002
\n\u30fb\u300c\u3057\u304b\u3057\u3001\u5b66\u3068\u307f\u5b50\u306fmost\u306f\u3001 day-7\u4ee5\u5916\u306e\u53ef\u80fd\u6027\u3082\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\uff1f\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\uff1f\uff1f\u300cday-7\u4ee5\u5916\u300d<\/span>\u3000\u3060\u3063\u305f\u3089clusters \u3067\u3057\u3087\uff1f\u4f55\u304c\u8a00\u3044\u305f\u3044\u306e\u3067\u3057\u3087\u3046\u304b\u306d\u3002
\n\u30fb\u300c\u3042\u3044\u307e\u3044\u306a\u82f1\u6587\u306b\u306a\u3063\u3066\u3044\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u5b66\u3068\u307f\u5b50\u306e\u60f3\u3044\u901a\u308a\u3067\u306a\u3044\u304b\u3089\u3042\u3044\u307e\u3044\u3060\u3068\u8a00\u3063\u3066\u3044\u308b\u3060\u3051\u3067\u3001\u5b66\u3068\u307f\u5b50\u306e\u60f3\u3044\u304c\u306a\u3051\u308c\u3070\u3001\u5f53\u305f\u308a\u524d\u306e\u308f\u304b\u308a\u3084\u3059\u3044\u82f1\u6587\u306a\u3093\u3067\u3059\u3002\u60f3\u3044\u3092\u7121\u7406\u306b\u62bc\u3057\u4ed8\u3051\u308b\u304b\u3089\u9593\u9055\u3044\u3060\u3068\u6279\u5224\u3055\u308c\u308b\u306e\u3067\u3059\u3002
\n\u30fb\u300c\u5b66\u3068\u307f\u5b50\u306f\u3001AI\u306b\u3001STAP\u8ad6\u6587\u306e\u5b9f\u9a13\u7d50\u679c\u3084\u56f3\u306e\u7d50\u679c\u3092\u8aac\u660e\u3057\u3066\u3001day-7\u4ee5\u5916\u306e\u53ef\u80fd\u6027\u3092\u805e\u3044\u3066\u307f\u305f\u3089\u3001AI\u306f\u3044\u308d\u3044\u308d\u82f1\u6587\u306e\u5019\u88dc\u3092\u3060\u3057\u3066\u304d\u3066\u3001\u3084\u308a\u3068\u308a\u304c\u9577\u304f\u306a\u308a\u307e\u3057\u305f\u3002\u300d<\/span>\u3000\u2190\u3000\u8cea\u554f\u304c\u60aa\u3044\u304b\u3089\u3067\u3059\u3002\u8cea\u554f\u306b\u5b66\u3068\u307f\u5b50\u306e\u504f\u898b\u3068\u5984\u60f3\u3068\u5618\u304c\u6df7\u3056\u3063\u3066\u3044\u308b\u4e0a\u306b\u975e\u8ad6\u7406\u7684\u306a\u65e5\u672c\u8a9e\u3060\u304b\u3089\u3067\u3057\u3087\u3046\u3002\u9055\u3046\u3068\u3044\u3046\u306e\u306a\u3089\u8cea\u554f\u306e\u5168\u6587\u3092\u516c\u958b\u3057\u305f\u3089\u3044\u3044\u3067\u3057\u3087\u3002
\n\u30fb\u300c\u5b66\u3068\u307f\u5b50\u306eAI\u3082\u3001Most day-7 clusters \/ that were large and contained more than a few dozen small cells \/ were positive for Oct4.\u3068\u8aad\u3080\u306e\u304c\u666e\u901a\u3068\u8a00\u3063\u3066\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u305d\u308a\u3083\u305d\u3046\u3067\u3057\u3087\u3002\u5b66\u3068\u307f\u5b50\u306e\u504f\u898b\u3068\u5984\u60f3\u3068\u5618\u304c\u306a\u3051\u308c\u3070\u3053\u306e\u901a\u308a\u306a\u3093\u3067\u3059\u3088\u3002\u300cAI\u306f\u3001\u30e6\u30fc\u30b6\u30fc\u306e\u610f\u5411\u306b\u6cbf\u3046\u3088\u3046\u306b\u3067\u304d\u3066\u3044\u307e\u3059\u3002\u300d<\/span>\u3068\u81ea\u5206\u3067\u8a00\u3063\u3066\u3044\u308b\u306e\u3060\u304b\u3089\u3001\u5ba2\u89b3\u7684\u306a\u8cea\u554f\u306b\u3059\u308c\u3070\u3044\u3044\u306e\u3055\u3002\u5ba2\u89b3\u7684\u306a\u8cea\u554f\u306b\u3059\u308b\u3068\u601d\u3063\u3066\u3044\u308b\u56de\u7b54\u304c\u51fa\u529b\u3055\u308c\u306a\u3044\u306e\u3067\u56f0\u3063\u3066\u3044\u308b\u3093\u3067\u3057\u3087\u3002\u5b9f\u9a13\u3067\u4eee\u5b9a\u901a\u308a\u306e\u7d50\u679c\u306b\u306a\u3089\u306a\u3044\u306e\u306f\u4eee\u5b9a\u304c\u9593\u9055\u3044\u306a\u306e\u3068\u540c\u3058\u306b\u3001\u671f\u5f85\u3057\u305f\u7b54\u3048\u304c\u51fa\u3066\u3053\u306a\u3044\u306e\u306f\u8cea\u554f\u304c\u9593\u9055\u3048\u3060\u304b\u3089\u3067\u3059\u3088\u3002
\n\u30fb\u300c\u5c0f\u7d30\u80de\u3092\u304b\u306a\u308a\u542b\u3080\u5927\u304d\u306a\u30af\u30e9\u30b9\u30bf\u30fc\u306f\u5149\u308b\u3068\u66f8\u3044\u3066\u3044\u308b\u3060\u3051\u3067\u3001\u305d\u308c\u4ee5\u5916\u306e\u3053\u3068\u306f\u66f8\u3044\u3066\u3042\u308a\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000\u9055\u3044\u307e\u3059\u3002\u300c\u5927\u304d\u306a\u30af\u30e9\u30b9\u30bf\u30fc\u306e\u591a\u304f\u306f\u5149\u308b\u300d\u3068\u66f8\u3044\u3066\u3042\u308b\u306e\u3067\u3059\u3002\u9055\u3044\u306f\u308f\u304b\u308b\u306e\u3067\u3057\u3087\uff1f
\n\u30fb\u300c\u3053\u3061\u3089\u306eAI\u306f\u3001\u3053\u308c\u4ee5\u5916\u306e\u8aad\u307f\u65b9\u304c\u3067\u304d\u308b\u3053\u3068\u3092\u6307\u6458\u3057\u3066\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u504f\u898b\u3068\u5984\u60f3\u3068\u5618\u3092\u6dfb\u3048\u305f\u304b\u3089\u3067\u3059\u3002
\n\u30fb\u300c\u3053\u3046\u3057\u305f\u4eba\u683c\u306e\u4eba\u306f\u3044\u308b\u306e\u3060\u304b\u3089\u3001\u76f8\u624b\u306b\u3057\u3066\u3044\u308b\u5b66\u3068\u307f\u5b50\u304c\u60aa\u3044\u3002\u300d<\/span>\u3000\u2190\u3000\u9055\u3044\u307e\u3059\u3002\u8ad6\u7406\u7684\u306b\u5b66\u3068\u307f\u5b50\u306e\u8a00\u3044\u5206\u304c\u5426\u5b9a\u3055\u308c\u3066\u3044\u308b\u306e\u306b\u3001\u7406\u89e3\u3067\u304d\u305a\u3001\u8ad6\u7406\u7684\u306a\u53cd\u8ad6\u3082\u3067\u304d\u305a\u3001\u53cd\u7701\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u5b66\u3068\u307f\u5b50\u304c\u60aa\u3044\u306e\u3067\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

STAP\u8ad6\u6587Article\u306eMETHODS\u306b\u3042\u308b\u30ad\u30e1\u30e9\u4f5c\u6210\u306e\u305f\u3081\u306eSTAP\u7d30\u80de\u584a\u306b\u3064\u3044\u3066\u306e\u82f1\u6587\u306b\u3064\u3044\u3066\u3001\u5b66\u3068\u307f\u5b50\u3068\u5f53\u65b9\u7b49\u3067\u89e3\u91c8\u304c\u7570\u306a\u308b\u3068\u3044\u3046\u306e\u304c\u524d\u8a18\u4e8b\u306e\u30b3\u30e1\u30f3\u30c8\u3067\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002\u524d\u8a18\u4e8b\u306e\u30b3\u30e1\u30f3\u30c8\u6570\u304c100\u4ef6\u306b\u8fd1\u3065\u3044\u305f\u306e\u3067\u65b0 … \u7d9a\u304d\u3092\u8aad\u3080 \u82f1\u6587\u79d1\u5b66\u8ad6\u6587\u306e\u8a18\u8ff0\u306f\u6587\u6cd5\u901a\u308a\u8aad\u3093\u3067\u306f\u3044\u3051\u306a\u3044<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8],"tags":[],"class_list":["post-25989","post","type-post","status-publish","format-standard","hentry","category-education","category-fake"],"_links":{"self":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25989"}],"version-history":[{"count":11,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25989\/revisions"}],"predecessor-version":[{"id":26002,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25989\/revisions\/26002"}],"wp:attachment":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}