{"id":25966,"date":"2024-11-25T07:26:19","date_gmt":"2024-11-24T22:26:19","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=25966"},"modified":"2024-12-06T16:05:38","modified_gmt":"2024-12-06T07:05:38","slug":"%e5%ad%a6%e3%81%a8%e3%81%bf%e5%ad%90%e3%81%aestap%e7%b4%b0%e8%83%9e%e3%81%9d%e3%81%ae%ef%bc%92","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=25966","title":{"rendered":"\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de\u305d\u306e\uff12"},"content":{"rendered":"

\u4ee5\u524d\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de<\/a>\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u3067\u8a18\u4e8b\u3092\u66f8\u304d\u307e\u3057\u305f\u304c\u3001\u6700\u8fd1”\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de”\u306e\u7279\u6027\u304c\u3055\u3089\u306b\u52a0\u308f\u308a\u307e\u3057\u305f\u306e\u3067\u3001\u8a18\u4e8b\u5185\u5bb9\u3092\u3001\u305d\u306e\uff12\u3068\u3057\u3066\u66f4\u65b0\u3057\u307e\u3059\u3002<\/p>\n

2022\/08\/08 \u306b\u5b66\u3068\u307f\u5b50\u306e\u610f\u5473\u3059\u308bSTAP\u7d30\u80de\u306f\u3001\u30ad\u30e1\u30e9\u306f\u4f5c\u308c\u306a\u3044<\/span>\u3063\u3066\u3001\u4ee5\u524d\u304b\u3089\u8a00\u3063\u3066\u308b\u3058\u3083\u306a\u3044\u306e\uff1f<\/a>\u3055\u3089\u306b\u300cSTAP\u7d30\u80de\u306f\u3001\u8907\u6570\u306e\u521d\u671f\u5316\u86cb\u767d\u3092\u5408\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u3066\u3082\u3001\u7d9a\u304f\u86cb\u767d\u5408\u6210\u3092\u30b9\u30e0\u30fc\u30ba\u306b\u9032\u307e\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u3002\u907a\u4f1d\u5b50\u5236\u5fa1\u304c\u884c\u304d\u8a70\u307e\u3063\u305f\u7d30\u80de\u306f\u3001ES\u4e26\u306e\u907a\u4f1d\u5b50\u72b6\u614b\u306b\u306f\u306a\u308c\u306a\u3044\u4e8b\u306f\u3001\u5bb9\u6613\u306b\u60f3\u50cf\u53ef\u80fd\u3060\u3002\u300d<\/span><\/a>\u3068\u8a00\u3063\u305f\u308f\u3051\u3067\u3059\u3002<\/p>\n

\u4eca\u56de\uff08 2024\/11\/21 \uff09\u3001\u5e79\u7d30\u80de\u3092\u4f5c\u308c\u308bSTAP\u7d30\u80de\u306f\u5b58\u5728\u3057\u307e\u305b\u3093\u3002\u4f4e\u30ec\u30d9\u30eb\u306e\u30ad\u30e1\u30e9\u3092\u4f5c\u308bSTAP\u7d30\u80de\u306f\u3042\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u5e79\u7d30\u80de\u306b\u306f\u306a\u308c\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/a>\u3068\u767a\u8a00\u3057\u305f\u308f\u3051\u3067\u3059\u3002<\/p>\n

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\n\uff1e\u5b66\u3068\u307f\u5b50
\n\u7570\u8b70\u304c\u3042\u308b\u306e\u306a\u3089\u3069\u3046\u305e\u3002\u304a\u5f85\u3061\u3057\u3066\u304a\u308a\u307e\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u304c\u5b9f\u9a13\u306e\u88cf\u4ed8\u3051\u3082\u306a\u3044\u7d30\u80de\u3092”\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de”\u3068\u3059\u308b\u306e\u306f\u52dd\u624b\u3067\u3059\u304c\u3001\u305d\u306e\u3088\u3046\u306a\u30ad\u30e1\u30e9\u306b\u5bc4\u4e0e\u3057\u306a\u3044\u5e79\u7d30\u80de\u306b\u3082\u306a\u3089\u306a\u3044\u7d30\u80de\u306e\u7814\u7a76\u306f\u3000\u300c\u751f\u547d\u73fe\u8c61\u306e\u6839\u5e79\u7406\u89e3\u306b\u7e4b\u304c\u308b\u77e5\u898b\u3092\u63d0\u4f9b\u3059\u308b\u300d<\/span>\u4e00\u7aef\u306b\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f
\n\uff1e\u5b66\u3068\u307f\u5b50
\n“\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de”\u306e\u89e3\u6790\u306f\u65b0\u3057\u3044\u77e5\u898b\u3092\u63d0\u4f9b\u3059\u308b\u3060\u308d\u3046\u3068\u3059\u308b\u306e\u306a\u3089\u3001\u3069\u306e\u3088\u3046\u306a\u77e5\u898b\u306b\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/span>\u3001\u3042\u308b\u3044\u306f\u3053\u306e\u3088\u3046\u306a\u9178\u6d74\u7d30\u80de\u3092\u7814\u7a76\u3059\u308b\u610f\u7fa9\u3068\u305d\u306e\u305f\u3081\u306b\u306f\u3069\u306e\u3088\u3046\u306a\u89e3\u6790\u304c\u5fc5\u8981\u306a\u306e\u304b\u3092\u304a\u7b54\u3048\u304f\u3060\u3055\u3063\u3066\u3082\u7d50\u69cb\u3067\u3059\u3002\u304a\u7b54\u3048\u3092\u5f85\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u8a71\u306f\u5909\u308f\u3063\u3066\u3001\u300care found\u300d\u306b\u3064\u3044\u3066\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u306f\u4e39\u7fbd\u6c0f\u7dcf\u8aac\u306b\u3042\u308b\u4e00\u6587\u300cAmong the TFs of the TSC-specific network, the evolutionarily conserved functions of Sox2, Eomes and Cdx2 are found <\/strong>in neuroectoderm, mesoendoderm and definitive endoderm,respectively, but they cooperate together to define an evolutionarily new cell type, the trophoblast.\u300d\u306e\u300care found\u300d\u3092\u300c\u305f\u3081\u606f\u3055\u3093\u305f\u3061\u306f\u3001\u300c\u5f15\u304d\u7d99\u304c\u308c\u308b \uff08are found\uff09\u300d\u306a\u308b\u65e5\u672c\u8a9e\u8868\u73fe\u3092\u3001TS\u304b\u3089\u5f15\u304d\u7d99\u304c\u308c\u308b\u3068\u8a33\u3059\u304b\u3089\u3001\u304a\u304b\u3057\u306a\u89e3\u91c8\u306b\u306a\u308b\u306e\u3067\u3059\u3002\u300d<\/span><\/a>\u3068\u8a00\u3063\u3066”are found”\u3092\u300c\u5f15\u304d\u7d99\u304c\u308c\u308b\u300d\u3068\u8a33\u3059\u306e\u306f\u3044\u3044\u306e\u3060\u304c\u300cTS\u300d\u304b\u3089\u300c\u4e09\u80da\u8449\u300d\u306b\u5f15\u304d\u7d99\u304c\u308c\u308b\u3068\u3059\u308b\u304b\u3089\u9593\u9055\u3044\u3060\u3068\u6307\u6458\u3057\u305f\u308f\u3051\u3067\u3059\u3002<\/p>\n

\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u5b66\u3068\u307f\u5b50\u306f\u300cTS\u306b\u4fdd\u5b58\u3055\u308c\u305f\u8ee2\u5199\u56e0\u5b50Sox2, Eomes Cdx2 \u304c\u3001\u305d\u306e\u5f8c\u306e\u5185\u3001\u4e2d\u3001\u5916\u306e\uff13\u80da\u8449\u7cfb\u306e\u7d30\u80de\u5206\u5316\u3001neuroectoderm, mesoendoderm\u3001definitive endoderm\u3000\u306b\u5f15\u304d\u7d99\u304c\u308c\u3066\u3044\u308b\u300d<\/span>\u3068\u8a33\u3057\u305f\u308f\u3051\u3067\u3059\u3002\u3064\u307e\u308a\u3053\u306e\u8a33\u3067\u306f\u300cTS\u306b\u4fdd\u5b58\u3055\u308c\u305f\u8ee2\u5199\u56e0\u5b50\u300d\u304c\u300c\u305d\u306e\u5f8c\u300d\u3001\u300c\u4e09\u80da\u8449\u306b\u5f15\u304d\u7d99\u304c\u308c\u3066\u3044\u308b\u300d\u3068\u3057\u304b\u89e3\u91c8\u3067\u304d\u307e\u305b\u3093\u3002\u305d\u3046\u3067\u306f\u306a\u3044\u3001\u6587\u6cd5\u7684\u306b\u3082\u8aa4\u308a\u306e\u3042\u308b\u6587\u7ae0\u3067\u306f\u306a\u304f\u3001\u8aad\u3080\u65b9\u304c\u8aa4\u8aad\u3057\u3066\u3044\u308b\u3068\u3059\u308b\u306e\u306a\u3089\u3001<\/span>\u300c\u4f55\u304c\u300d\u300c\u4f55\u304b\u3089\u300d\u300c\u4f55\u306b\u300d\u5f15\u304d\u7d99\u304c\u308c\u305f<\/span>\u306e\u304b\u3001\u518d\u5ea6\u3001\u89e3\u8aac\u3057\u3066\u3044\u305f\u3060\u3051\u308b\u3088\u3046\u4f0f\u3057\u3066\u304a\u9858\u3044\u3059\u308b\u3068\u3053\u308d\u3067\u3059\u3002\u3053\u306e”are found”\u306b\u3064\u3044\u3066\u306e\u5f53\u65b9\u306e\u610f\u898b\u306f\u65e2\u306bare found \u2026<\/a>\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u306e\u3067\u3053\u308c\u3092\u8e0f\u307e\u3048\u3066\u304a\u7b54\u3048\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u5f53\u65b9\u306f\u3001\u5b66\u3068\u307f\u5b50\u69d8\u304b\u3089\u306e\u8cea\u554f\u306b\u7b54\u3048\u3066\u3044\u307e\u3059\u3002\u79d1\u5b66\u7684\u8b70\u8ad6\u306b\u306f\u8cea\u7591\u5fdc\u7b54\u304c\u5fc5\u9808\u3067\u3001\u5b66\u3068\u307f\u5b50\u69d8\u306f\u79d1\u5b66\u7684\u8b70\u8ad6\u3092\u3057\u305f\u3044\u3068\u65e5\u9803\u304a\u3063\u3057\u3083\u3063\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u69d8\u306b\u3042\u3063\u3066\u3082\u89e3\u7b54\u3057\u3066\u3044\u305f\u3060\u3051\u308b\u3088\u3046\u304a\u9858\u3044\u3057\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4ee5\u524d\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de\u3068\u3044\u3046\u30bf\u30a4\u30c8\u30eb\u3067\u8a18\u4e8b\u3092\u66f8\u304d\u307e\u3057\u305f\u304c\u3001\u6700\u8fd1”\u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de”\u306e\u7279\u6027\u304c\u3055\u3089\u306b\u52a0\u308f\u308a\u307e\u3057\u305f\u306e\u3067\u3001\u8a18\u4e8b\u5185\u5bb9\u3092\u3001\u305d\u306e\uff12\u3068\u3057\u3066\u66f4\u65b0\u3057\u307e\u3059\u3002 2022\/08\/08 \u306b\u5b66\u3068\u307f\u5b50\u306e … \u7d9a\u304d\u3092\u8aad\u3080 \u5b66\u3068\u307f\u5b50\u306eSTAP\u7d30\u80de\u305d\u306e\uff12<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8],"tags":[],"class_list":["post-25966","post","type-post","status-publish","format-standard","hentry","category-education","category-fake"],"_links":{"self":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25966","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25966"}],"version-history":[{"count":6,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25966\/revisions"}],"predecessor-version":[{"id":25972,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/25966\/revisions\/25972"}],"wp:attachment":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25966"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25966"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25966"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}