{"id":25158,"date":"2024-04-22T11:07:12","date_gmt":"2024-04-22T02:07:12","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=25158"},"modified":"2024-05-11T15:13:39","modified_gmt":"2024-05-11T06:13:39","slug":"%e7%9c%81%e7%95%a5%e3%81%8c%e8%aa%ad%e3%81%bf%e5%8f%96%e3%82%8c%e3%81%aa%e3%81%84","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=25158","title":{"rendered":"\u7701\u7565\u304c\u8aad\u307f\u53d6\u308c\u306a\u3044&#8230;"},"content":{"rendered":"<p><a href=\"https:\/\/nbsigh2.com\/?p=25126\" target=\"_blank\" rel=\"noopener noreferrer\">\u524d\u306e\u8a18\u4e8b<\/a>\u306e\u30b3\u30e1\u30f3\u30c8\u6b04\u306e<a href=\"https:\/\/nbsigh2.com\/?p=25126#comment-30690\" target=\"_blank\" rel=\"noopener noreferrer\">\u6700\u5f8c\u306b\u66f8\u3044\u305f\u3053\u3068<\/a>\u3067\u3059\u304c\u3001\u30b3\u30e1\u30f3\u30c8\u304c100\u4ef6\u306b\u306a\u308b\u306e\u3067\u3001\u540c\u3058\u5185\u5bb9\u3092\u8a18\u4e8b\u3068\u3057\u3066\u65b0\u305f\u306b\u5efa\u3066\u308b\u3053\u3068\u306b\u3057\u307e\u3057\u305f\u3002\u540c\u3058\u3053\u3068\u306e\u7e70\u308a\u8fd4\u3057\u3067\u7533\u3057\u8a33\u3042\u308a\u307e\u305b\u3093\u3002\u306a\u306b\u305b\u65b0\u3057\u3044\u8a18\u4e8b\u3092\u5efa\u3066\u308b\u8a71\u984c\u3092\u6b20\u3044\u3066\u3044\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n<p>\u5b66\u3068\u307f\u5b50\u304c\u4e39\u7fbd\u6c0f\u7dcf\u8aac\u306e\u82f1\u6587\u300cAmong the TFs of the TSC-specific network, the evolutionarily conserved functions of Sox2, Eomes and Cdx2 are found in neuroectoderm, mesoendoderm and definitive endoderm, respectively, but they cooperate together to define an evolutionarily new cell type, the trophoblast. \u300d\u3092\u610f\u8a33\u3057\u3066<a href=\"https:\/\/katura1.blog.fc2.com\/blog-entry-1371.html\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #0000ff;\">\u300cTS\u306b\u4fdd\u5b58\u3055\u308c\u305f\u8ee2\u5199\u56e0\u5b50Sox2, Eomes Cdx2 \u304c\u3001\u305d\u306e\u5f8c\u306e\u5185\u3001\u4e2d\u3001\u5916\u306e\uff13\u80da\u8449\u7cfb\u306e\u7d30\u80de\u5206\u5316\u3001neuroectoderm, mesoendoderm\u3001definitive endoderm\u3000\u306b\u5f15\u304d\u7d99\u304c\u308c\u3066\u3044\u308b\u3002\u300d<\/span><\/a>\u3068\u3057\u305f\u306e\u3067\u3059\u3002<\/p>\n<p>\u8ab0\u304c\u8aad\u3093\u3067\u3082\u5b66\u3068\u307f\u5b50\u306e\u6587\u7ae0\u306f<span style=\"color: #0000ff;\">\u300cTS\u306b\u4fdd\u5b58\u3055\u308c\u305f\u8ee2\u5199\u56e0\u5b50\u304c\u305d\u306e\u5f8c\u306e\u5185\u3001\u4e2d\u3001\u5916\u306e\uff13\u80da\u8449\u7cfb\u306b\u5f15\u304d\u7d99\u304c\u308c\u3066\u3044\u308b\u3002\u300d<\/span>\u3068\u89e3\u91c8\u3059\u308b\u3057\u304b\u306a\u3044\u306e\u3067\u3001\u5f53\u65b9\u3082plus99%\u3055\u3093\u3082\u3001\u300c\u4e09\u80da\u8449\u306b\u5f15\u304d\u7d99\u304c\u308c\u308b\u300d\u3068\u3044\u3046\u306e\u306f\u9806\u756a\u304c\u9006\u3060\u3068\u6307\u6458\u3057\u305f\u308f\u3051\u3067\u3059\u3002<\/p>\n<p>\u3057\u304b\u3057\u3001\u5b66\u3068\u307f\u5b50\u306f\u3053\u306e\u8a33\u306e<a href=\"https:\/\/katura1.blog.fc2.com\/blog-entry-2390.html\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #0000ff;\">\u300c\u300c\u305d\u306e\u5f8c\u306e\u300d\u306e\u524d\u306b\u306f\u3001\u8a00\u8449\u306e\u7701\u7565\u304c\u3042\u308b\u300d<\/span><\/a>\u304b\u3089<span style=\"color: #0000ff;\">\u300c\u300cTS\u5f8c\u300d\u3068\u8aad\u3093\u3067\u306f\u3044\u3051\u306a\u3044\u3002TS\u304b\u3089\u4e09\u80da\u8449\u304c\u751f\u3058\u3066\u6765\u308b\u3068\u30a4\u30e1\u30fc\u30b8\u3059\u308b\u306e\u306f\u30c8\u30f3\u30c7\u30e2\u8aa4\u8aad\u3060\u300d\u3001\u300c\u30c8\u30f3\u30c7\u30e2\u8aa4\u8aad\u3092\u30cd\u30bf\u306b\u3001\u6570\u5e74\u306b\u308f\u305f\u308a\u3001\u5acc\u304c\u3089\u305b\u3092\u7d9a\u3051\u3066\u3044\u308b\u300d<\/span>\u3068\u3044\u3046\u308f\u3051\u3067\u3059\u3002<\/p>\n<p>\u305d\u3053\u3067\u3001\u5f53\u65b9\u304c\u4f55\u304c\u7701\u7565\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u6559\u3048\u3066\u9802\u6234\u3068\u304a\u9858\u3044\u3057\u3066\u3044\u308b\u306e\u304c\u3001\uff14\u6708\uff12\uff12\u65e5\uff08\u6708\uff09\u306e\u5348\u524d\u306e\u6642\u70b9\u3067\u3059\u3002\u304a\u7b54\u3048\u304c\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u5f53\u65b9\u304c\u4e39\u7fbd\u6c0f\u306e\u82f1\u6587\u3092\u4e01\u5be7\u306b\u3001\u5b66\u3068\u307f\u5b50\u304c\u308f\u304b\u308b\u3088\u3046\u306b\u30d0\u30ab\u4e01\u5be7\u306b\u7ffb\u8a33\u3057\u305f\u306e\u3067\u3001\u5b66\u3068\u307f\u5b50\u304c\uff14\u5e74\u304b\u304b\u3063\u3066\u3001\u3088\u3046\u3084\u304f\u6b63\u3057\u304f\u7406\u89e3\u3067\u304d\u305f\u3002\u3060\u304b\u3089\u5f53\u65b9\u306f\u5b66\u3068\u307f\u5b50\u304c\u8aa4\u308a\u3067\u3042\u308b\u524d\u8a00\u306b\u4f55\u304b\u3092\u52a0\u3048\u3066\u3001\u300c\u4e09\u80da\u8449\u306b\u5f15\u304d\u7d99\u304c\u308c\u308b\u300d\u306e\u610f\u5473\u3092\u3072\u3063\u304f\u308a\u8fd4\u305d\u3046\u3068\u753b\u7b56\u3057\u3066\u3044\u308b\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002\u3069\u306e\u3088\u3046\u306a\u8a9e\u53e5\u304c\u7701\u7565\u3055\u308c\u3066\u3044\u308b\u304b\u3089\u3001\u300c\u4e09\u80da\u8449\u306b\u5f15\u304d\u7d99\u304c\u308c\u308b\u300d\u304c\u9006\u8ee2\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u3082\u3057\u9032\u5316\u7684\u306b\u6804\u990a\u819c\u306e\u307b\u3046\u304c\u4e09\u80da\u8449\u306b\u6bd4\u3079\u5f8c\u304b\u3089\u3067\u304d\u308b\u3068\u3044\u3046\u8a8d\u8b58\u304c\u3042\u308b\u306e\u306a\u3089\u3001\u81ea\u5206\u306e\u66f8\u3044\u305f\u65e5\u672c\u8a9e\u304c\u30c7\u30bf\u30e9\u30e1\u3067\u3042\u3063\u305f\u3068\u8a00\u3048\u3070\u3044\u3044\u306e\u3067\u3059\u3088\u3002\u305d\u3057\u3066<span style=\"color: #0000ff;\">\u300c\u30c8\u30f3\u30c7\u30e2\u8aa4\u8aad\u3060\u300d<\/span>\u3068\u3044\u3046\u306e\u306f\u8b1d\u7f6a\u3057\u3066\u8a02\u6b63\u3059\u308c\u3070\u3044\u3044\u306e\u3067\u3059\u3088\u3002<\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/nbsigh2.com\/wp-content\/uploads\/2024\/04\/20240422azalea.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-25164 size-medium\" src=\"https:\/\/nbsigh2.com\/wp-content\/uploads\/2024\/04\/20240422azalea-300x300.png\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/nbsigh2.com\/wp-content\/uploads\/2024\/04\/20240422azalea-300x300.png 300w, https:\/\/nbsigh2.com\/wp-content\/uploads\/2024\/04\/20240422azalea-150x150.png 150w, https:\/\/nbsigh2.com\/wp-content\/uploads\/2024\/04\/20240422azalea.png 600w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><br 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