{"id":24600,"date":"2023-08-30T08:30:33","date_gmt":"2023-08-29T23:30:33","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=24600"},"modified":"2023-09-13T08:37:36","modified_gmt":"2023-09-12T23:37:36","slug":"handling-issues","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=24600","title":{"rendered":"handling issues"},"content":{"rendered":"

handling issues \u3068\u306f\u3001\u300c\u53d6\u308a\u6271\u3044\u306e\u554f\u984c\u300d\u3068\u3044\u3046\u610f\u5473\u3060\u3068\u601d\u3046\u306e\u3067\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u306b\u3088\u308b\u3068\u300c\u308f\u304b\u308a\u307e\u305b\u3093\u3068\u3044\u3046\u610f\u5473\u306e\u4ee3\u8868\u300d\u3060\u3068\u3044\u3046\u308f\u3051\u3067\u3059\u3002<\/p>\n

\u7e70\u308a\u8fd4\u3057\u3067\u3059\u304cDetection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR <\/a>\u3068\u3044\u3046\u8ad6\u6587\u306e\u7d50\u679c\u306e\u4e00\u756a\u6700\u5f8c\u3001Disussion\u306e\u76f4\u524d\u306e\u300cExclusivity of 2019 novel coronavirus based on clinical samples pre-tested positive for other respiratory viruses\u300d\u3068\u3044\u3046\u30bb\u30af\u30b7\u30e7\u30f3\u306b\u3042\u308b\u8a18\u8ff0\u300cIn four individual test reactions, weak initial reactivity was seen but they were negative upon retesting with the same assay. These signals were not associated with any particular virus, and for each virus with which initial positive reactivity occurred, there were other samples that contained the same virus at a higher concentration but did not test positive. Given the results from the extensive technical qualification described above, it was concluded that this initial reactivity was not due to chemical instability of real-time PCR probes but most probably to handling issues<\/span> caused by the rapid introduction of new diagnostic tests and controls during this evaluation study.\u300d\uff08\u500b\u3005\u306e4\u3064\u306e\u691c\u67fb\u53cd\u5fdc\u3067\u306f\u3001\u521d\u671f\u306b\u5f31\u3044\u53cd\u5fdc\u6027\u304c\u898b\u3089\u308c\u305f\u304c\u3001\u540c\u3058\u30a2\u30c3\u30bb\u30a4\u3067\u518d\u691c\u67fb\u3057\u305f\u3068\u3053\u308d\u9670\u6027\u3067\u3042\u3063\u305f\u3002\u3053\u308c\u3089\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u7279\u5b9a\u306e\u30a6\u30a4\u30eb\u30b9\u306b\u95a2\u9023\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u521d\u671f\u53cd\u5fdc\u6027\u304c\u967d\u6027\u3068\u306a\u3063\u305f\u5404\u30a6\u30a4\u30eb\u30b9\u306b\u3064\u3044\u3066\u3001\u540c\u3058\u30a6\u30a4\u30eb\u30b9\u3092\u9ad8\u6fc3\u5ea6\u3067\u542b\u3080\u304c\u967d\u6027\u3068\u306a\u3089\u306a\u304b\u3063\u305f\u4ed6\u306e\u30b5\u30f3\u30d7\u30eb\u3082\u3042\u3063\u305f\u3002\u4e0a\u8ff0\u306e\u5e83\u7bc4\u306a\u6280\u8853\u7684\u691c\u8a3c\u306e\u7d50\u679c\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u3053\u306e\u521d\u671f\u306e\u53cd\u5fdc\u306f\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0PCR\u30d7\u30ed\u30fc\u30d6\u306e\u5316\u5b66\u7684\u4e0d\u5b89\u5b9a\u6027\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u304a\u305d\u3089\u304f\u3053\u306e\u8a55\u4fa1\u7814\u7a76\u4e2d\u306b\u65b0\u3057\u3044\u8a3a\u65ad\u691c\u67fb\u3068\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u6025\u901f\u306b\u5c0e\u5165\u3057\u305f\u305f\u3081\u306b\u751f\u3058\u305f\u53d6\u308a\u6271\u3044\u4e0a\u306e\u554f\u984c\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308b\u3068\u7d50\u8ad6\u3065\u3051\u3089\u308c\u305f\u3002\uff08www.DeepL.com\/Translator\u306e\u7ffb\u8a33\u3092\u53c2\u8003\u306b\u3057\u307e\u3057\u305f\u3002)\u300d\u306b\u3042\u308b\u300chandling issues\u300d\u306e\u8a33\u304c\u554f\u984c\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u305d\u306e\u524d\u306b\u3061\u3068\u8107\u9053\u306b\u305d\u308c\u307e\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u304c\u3001\u307e\u3060\u81ea\u5206\u306e\u8aa4\u308a\u3092\u8a8d\u3081\u305a\u3001\u3057\u3064\u3053\u304f\u8a33\u306e\u308f\u304b\u3089\u306a\u3044\u3053\u3068\u3092\u8a00\u3044\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n

plus\u3055\u3093\u306f\u3001\u5fae\u5999\u53cd\u5fdc\u304c\u66f8\u304b\u308c\u3066\u3044\u308b\u3068\u4e3b\u5f35\u3057\u3001\u66f8\u304b\u308c\u3066\u3044\u308b\u306e\u306b\u3001\u5b66\u3068\u307f\u5b50\u306f\u300c\u4e0d\u660e\u300d\u3068\u3044\u3046\u306e\u306f\u3001\u5b66\u3068\u307f\u5b50\u306f\u82f1\u8a9e\u304c\u3088\u3081\u3066\u3044\u306a\u3044\u304b\u3089\u3060\u3068\u3001plus\u3055\u3093\u306f\u8003\u3048\u308b\u3002<\/a>\u3000\u2190\u3000\u610f\u5473\u4e0d\u660e\u3067\u3059\u3002\u65e5\u672c\u8a9e\u306b\u4e0d\u81ea\u7531\u306a\u5b66\u3068\u307f\u5b50\u306f\u5c0f\u5b66\u751f\u306e\u4f5c\u6587\u306b\u3082\u52a3\u308b\u6587\u7ae0\u3057\u304b\u66f8\u3051\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n

\u3053\u306e\u5b66\u3068\u307f\u5b50\u306e\u767a\u8a00\u306fplus99%\u3055\u3093\u306e2023\u5e748\u670829\u65e5 22:59\u306e\u30b3\u30e1\u30f3\u30c8<\/a>\u306b\u5bfe\u3059\u308b\u30b3\u30e1\u30f3\u30c8\u3067\u3059\u3002<\/p>\n

\u306a\u3093\u3068\u304b\u5b66\u3068\u307f\u5b50\u306e\u610f\u3092\u6c72\u307f\u53d6\u3063\u3066\u66f8\u3044\u3066\u307f\u308b\u3068\u5b66\u3068\u307f\u5b50\u306f\u5fae\u5999\u5224\u5b9a\u304c\u66f8\u304b\u308c\u3066\u3044\u308b\u3068\u4e3b\u5f35\u3057\u3066\u3044\u3066\u3001\u5b9f\u969b\u306b\u5fae\u5999\u5224\u5b9a\u304c\u66f8\u304b\u308c\u3066\u3044\u308b\u306e\u3060\u304c\u3001plus99%\u3055\u3093\u306f\u300c\u5b66\u3068\u307f\u5b50\u306f\u82f1\u8a9e\u3092\u8aad\u3081\u3066\u306a\u3044\u304b\u3089\u3001\u5b66\u3068\u307f\u5b50\u306f\u4e0d\u660e\u3060\u3068\u8aa4\u3063\u3066\u89e3\u91c8\u3057\u3066\u3044\u308b\u300d\u3068\u3057\u3066\u3044\u308b\u3002<\/span>\u3000\u9055\u3046\u304b\uff1f\u3044\u305a\u308c\u306b\u3057\u308d\u610f\u5473\u4e0d\u660e\u3067\u3059\u306a\u3002\u3069\u3046\u3084\u308b\u3068\u3053\u306e\u3088\u3046\u306a\u610f\u5473\u4e0d\u660e\u306a\u6587\u7ae0\u3092\u66f8\u304f\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n

\u300cplus\u3055\u3093\u306f\u3001\u5fae\u5999\u53cd\u5fdc\u304c\u66f8\u304b\u308c\u3066\u3044\u308b\u3068\u4e3b\u5f35\u300d<\/span>\u3000\u2190\u3000\u3082\u3057\u4e3b\u5f35\u3057\u3066\u3044\u308b\u306e\u304cplus99%\u3055\u3093\u3067\u3042\u308b\u3068\u8aad\u3080\u3068\u3001\u3053\u308c\u306f\u9593\u9055\u3044\u3067\u3059\u3002\u300c\u5fae\u5999\u53cd\u5fdc\u304c\u66f8\u304b\u308c\u3066\u3044\u308b\u3068\u4e3b\u5f35\u300d\u3068\u3057\u3066\u3044\u308b\u306e\u306f\u5b66\u3068\u307f\u5b50\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u304c\u5f53\u65b9\u306b\u5bfe\u3057PCR\u691c\u67fb\u306b\u304a\u3051\u308b\u5fae\u5999\u53cd\u5fdc\u306e\u539f\u56e0\u3092\u7a76\u660e\u3067\u304d\u306a\u3044\u8b0e\u306f\u3001\u6839\u5e79\u7684\u3068\u8a00\u3048\u308b\u3082\u306e\u3067\u3059\u3067\u3059\u3002\u65e5\u672c\u8a9e\u3057\u3063\u304b\u308a\u7406\u89e3\u3059\u308b\u3088\u3046\u306b\u306d\u3002\u5b66\u8005\u306a\u3093\u3060\u304b\u3089\u3002<\/a>\u3068\u767a\u8a00\u3057\u305f\u3053\u3068\u3092\u6349\u3048\u3066plus99%\u3055\u3093\u304c\u30b3\u30e1\u30f3\u30c8\u3055\u308c\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u66f0\u304f\uff1a\u8ad6\u6587\u8457\u8005\u306b\u306f\u5fae\u53cd\u5fdc\u306e\u539f\u56e0\u306f\u8ffd\u6c42\u3067\u304d\u306a\u3044\u3060\u308d\u3046\u3068\u3001\u307e\u3068\u3082\u306a\u8aad\u8005\u306f\u8003\u3048\u308b\u3002\u3060\u304b\u3089\u3001\u8a00\u3044\u8a33\u6587\u7ae0\u306f\u8aad\u307f\u98db\u3070\u3059\u3002\u305f\u3081\u606f\u3001plus\u3055\u3093\u306e\u3088\u3046\u306b\u6ce8\u76ee\u3057\u307e\u305b\u3093\u3002\u3064\u307e\u308a\u3001\u5fae\u5999\u53cd\u5fdc\u306e\u78ba\u7387\u304c\u4f4e\u3044\u306a\u3089\u3001\u691c\u67fb\u6cd5\u3068\u3057\u3066\u6709\u7528\u3060\u3068\u3001\u307e\u3068\u3082\u306a\u8aad\u8005\u306f\u8003\u3048\u308b\u3002<\/span><\/p><\/blockquote>\n

\u2190\u3000\u3053\u308c\u3082\u610f\u5473\u4e0d\u660e\u3067\u3059\u3002\u306a\u305c\u306a\u3089\u3001\u8a72\u5f53\u8ad6\u6587\u306e\u8a72\u5f53\u82f1\u6587\u306f\u7d50\u679c\u306e\u4e00\u756a\u6700\u5f8c\u306b\u66f8\u3044\u3066\u3042\u308b”\u8a00\u3044\u8a33”\u3068\u3057\u3066\u3082\u3044\u3044\u3088\u3046\u306a\u8aac\u660e\u3067\u3059\u304b\u3089\u3001\u300c\u8aad\u307f\u98db\u3070\u300d<\/span>\u3057\u3066\u3082\u554f\u984c\u306a\u3044\u306e\u306b\u3001\u5b66\u3068\u307f\u5b50\u304c\u300c\u6839\u5e79\u7684\u554f\u984c\u300d<\/span>\u3060\u3068\u53d6\u308a\u4e0a\u3052\u305f\u306e\u3067\u3059\u3002\u6ce8\u76ee\u3057\u305f\u306e\u306f\u300c\u305f\u3081\u606f\u3001plus\u3055\u3093\u300d<\/span>\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u306a\u306e\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u304c\u5618\u3092\u66f8\u3044\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n

\u3055\u3066handling issues \u3067\u3059\u304c\u5b66\u3068\u307f\u5b50\u306e\u8a00\u3044\u5206\u3067\u3059\u3002
\n\u300chandling issues\u306f\u3001\u3059\u3079\u3066\u306e\u7591\u554f\u3092\u542b\u3080\u8a00\u8449\u3067\u3042\u3063\u3066\u3001\u300c\u308f\u304b\u308a\u307e\u305b\u3093\u3068\u3044\u3046\u610f\u5473\u3067\u3059\u3002\uff0a\u300d<\/span>\u3000\u2190\u3000\u3093\u304c\u3002
\n\uff08\uff0a\u3000\uff13\uff10\u65e5\u671d\u306b\u66f8\u304d\u63db\u3048\u304c\u3042\u3063\u3066\u300chandling issues\u306f\u3001\u3059\u3079\u3066\u306e\u7591\u554f\u3092\u542b\u3080\u8a00\u8449\u3067\u3042\u3063\u3066\u3001\u300c\u308f\u304b\u308a\u307e\u305b\u3093\u3068\u3044\u3046\u610f\u5473\u3092\u4ee3\u8868\u3057\u307e\u3059\u3002\u300d\u3068\u306a\u308a\u307e\u3057\u305f\uff09<\/p>\n

handling issues\u3068\u306f
\nDeepL:\u554f\u984c\u51e6\u7406\u3001\u53d6\u308a\u6271\u3044\u4e8b\u9805\u3001\u53d6\u308a\u6271\u3044\u554f\u984c\u3001\u53d6\u308a\u6271\u3044\u8ab2\u984c
\nGoogle\u7ffb\u8a33\uff1a\u554f\u984c\u306e\u51e6\u7406
\n\u3068\u306e\u3053\u3068\u3067\u3059\u3002\u7269\u54c1\u306e\u53d6\u308a\u6271\u3044\u3001\u30b5\u30f3\u30d7\u30eb\u306e\u64cd\u4f5c\u624b\u9806\u3000\u3068\u304b\u8a00\u3046\u610f\u5473\u3067\u3059\u3088\u306d\u3002\u4f8b\u3048\u3070\u691c\u4f53\u306b\u30d0\u30c3\u30d5\u30a1\u30fc\u3092\u52a0\u3048\u3001\u9060\u6c88\u3055\u305b\u3001\u308d\u904e\u3057\u3001\uff58\uff58\u5206\u9593\uff58\uff58\u5ea6\u306b\u4fdd\u3061\u3001\u30d7\u30ed\u30fc\u30d6\u3092\u6295\u5165\u3057\u3001…. \u3068\u304b\u306e\u624b\u9806\u306e\u3053\u3068\u3068\u601d\u3046\u308f\u3051\u3067\u3059\u3002\u6c7a\u3057\u3066\u300c\u308f\u304b\u308a\u307e\u305b\u3093\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u306a\u3044\u3067\u3059\u306a\u3002<\/p>\n

\u539f\u6587\uff1a\u300cinitial reactivity was not due to chemical instability of real-time PCR probes but most probably to handling issues<\/span> caused by the rapid introduction of new diagnostic tests and controls during this evaluation study.\u300d
\n\u666e\u901a\u306f\uff1b
\n\u300c\uff08\u3053\u306e\u30a8\u30e9\u30fc\u304c\u751f\u3058\u305f\u3068\u3044\u3046\uff09\u521d\u671f\u306e\u53cd\u5fdc\u306f\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0PCR\u30d7\u30ed\u30fc\u30d6\u306e\u5316\u5b66\u7684\u4e0d\u5b89\u5b9a\u6027\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u304a\u305d\u3089\u304f\u3053\u306e\u8a55\u4fa1\u7814\u7a76\u4e2d\u306b\u65b0\u3057\u3044\u8a3a\u65ad\u30c6\u30b9\u30c8\u3068\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u6025\u901f\u306b\u5c0e\u5165\u3057\u305f\u3053\u3068\u306b\u3088\u308b\u53d6\u308a\u6271\u3044\u306e\u554f\u984c<\/span>\u3067\u3042\u308d\u3046\u300d
\n\u3067\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u306e\u8a00\u3046\u901a\u308a\u306b\u8a33\u3059\u3068\uff1b
\n\u300c\uff08\u3053\u306e\u30a8\u30e9\u30fc\u304c\u751f\u3058\u305f\u3068\u3044\u3046\uff09\u521d\u671f\u306e\u53cd\u5fdc\u306f\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0PCR\u30d7\u30ed\u30fc\u30d6\u306e\u5316\u5b66\u7684\u4e0d\u5b89\u5b9a\u6027\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u304a\u305d\u3089\u304f\u3053\u306e\u8a55\u4fa1\u7814\u7a76\u4e2d\u306b\u65b0\u3057\u3044\u8a3a\u65ad\u30c6\u30b9\u30c8\u3068\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u6025\u901f\u306b\u5c0e\u5165\u3057\u305f\u305f\u3053\u3068\u306b\u3088\u308b\u300c\u3042\u3089\u3086\u308b\u554f\u984c\u306e\u3053\u3068\u3067\u3001\u3069\u308c\u304b\u304c\u539f\u56e0\u304b\u306f\u308f\u304b\u308a\u307e\u305b\u3093\u300d<\/span>\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u304c\u3001\u3044\u3044\u306e\u3067\u3059\u304b\u306d\uff1f<\/p>\n

\uff1e\u5b66\u3068\u307f\u5b50
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\n\u2190\u3000\u5f53\u65b9\u7b49\u306e\u3069\u306e\u3088\u3046\u306a\u8a00\u52d5\u3092\u6349\u3048\u3066\u3001\u5f53\u65b9\u7b49\u306b\u81ea\u7701\u304c\u306a\u3044\u3068\u3044\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u5177\u4f53\u7684\u306b\u6307\u6458\u3067\u304d\u306a\u3044\u308f\u3051\u3067\u3001\u3044\u3064\u3082\u306e\u300c\u304a\u524d\u306e\u304b\u30fc\u3061\u3083\u3093\u30c7\u30d9\u30bd\u300d\u3067\u3059\u306d\u3002<\/p>\n

\"\"<\/a>
\n\u767e\u5408<\/p>\n","protected":false},"excerpt":{"rendered":"

handling issues \u3068\u306f\u3001\u300c\u53d6\u308a\u6271\u3044\u306e\u554f\u984c\u300d\u3068\u3044\u3046\u610f\u5473\u3060\u3068\u601d\u3046\u306e\u3067\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u306b\u3088\u308b\u3068\u300c\u308f\u304b\u308a\u307e\u305b\u3093\u3068\u3044\u3046\u610f\u5473\u306e\u4ee3\u8868\u300d\u3060\u3068\u3044\u3046\u308f\u3051\u3067\u3059\u3002 \u7e70\u308a\u8fd4\u3057\u3067\u3059\u304cDetection of 2019 novel cor … \u7d9a\u304d\u3092\u8aad\u3080 handling issues<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8],"tags":[],"class_list":["post-24600","post","type-post","status-publish","format-standard","hentry","category-education","category-fake"],"_links":{"self":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/24600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24600"}],"version-history":[{"count":13,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/24600\/revisions"}],"predecessor-version":[{"id":24616,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/24600\/revisions\/24616"}],"wp:attachment":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}