{"id":23989,"date":"2023-03-29T12:05:30","date_gmt":"2023-03-29T03:05:30","guid":{"rendered":"https:\/\/nbsigh2.com\/?p=23989"},"modified":"2023-04-03T11:31:43","modified_gmt":"2023-04-03T02:31:43","slug":"%e4%b8%ad%e9%ab%98%e7%94%9f%e8%8b%b1%e8%aa%9e%e3%81%ae%e7%9f%a5%e8%ad%98%e3%82%92%e3%80%81%e6%83%85%e3%81%91%e3%81%aa%e3%81%84%e3%81%a7%e3%81%99%e3%81%ad","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=23989","title":{"rendered":"\u4e2d\u9ad8\u751f\u82f1\u8a9e…\u60c5\u3051\u306a\u3044\u3067\u3059\u306d"},"content":{"rendered":"

\u5f53\u65b9\u7b49\u304c\u3001\u5b66\u3068\u307f\u5b50\u306e\u82f1\u8a9e\u306e\u89e3\u91c8\u304c\u9593\u9055\u3044\u3060\u3068\u3044\u3063\u305f\u3089\u3001\u305f\u3081\u606f\u3055\u3093\u306f\u81ea\u8eab\u306e\u6b63\u5f53\u6027\u3092\u4e3b\u5f35\u3059\u308b\u6642\u306f\u3001\u3044\u3064\u3082\u4e2d\u9ad8\u751f\u82f1\u8a9e\u306e\u77e5\u8b58\u3092\u6301\u3061\u51fa\u3057\u307e\u3059\u3002\u60c5\u3051\u306a\u3044\u3067\u3059\u306d\u3002<\/a>\u3068\u306e\u3053\u3068\u3067\u3059\u3002however\u3001 therefore\u3001 among\u3001 exclusive…\u4e2d\u9ad8\u751f\u30ec\u30d9\u30eb\u306e\u82f1\u8a9e\u80fd\u529b\u304c\u5b66\u3068\u307f\u5b50\u306b\u306a\u3044\u304b\u3089\u306a\u3093\u3067\u3059\u3051\u3069\u306d\u3002<\/p>\n

FES1\u3001FLS3\u3001CTS1\u3001129\/GFP\u3000\u306e\u95a2\u4fc2\u306e\u3053\u3068\u3067\u3059\u3002\u7531\u6765\u7d30\u80de\u306a\u306e\u304b\u540c\u3058\u7d30\u80de\u306a\u306e\u304b\u306e\u82f1\u8a9e\u89e3\u91c8\u3067\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u306fBCA\u8ad6\u6587\u306e<\/p>\n

An ES cell stock, 129\/GFP ES, was also found to share all these genomic features (Extended Data Table 1).After the above three SNP clusters reflecting parental heterogeneity are excluded, the remaining 1,290 SNP alleles that distinguish FES1 and FES2 are supposed to have accumulated at or after establishment in 2005. Regarding these SNPs, STAP cell lies FLS3 and CTS1 and 129\/GFP ES cells are nearly identical, but differ slightly from FES1 (at 30% of these alleles), suggesting that STAP cell lines FLS and CTS were derived from a sub-stock of FES1 ES cells.<\/p><\/blockquote>\n

\u3092\u5f15\u7528\u3057\u3066\u300c\u3053\u306e\u60c5\u5831\u3092\u81ea\u3089\u306e\u56f3\u5f0f\u5316\u306b\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3092\u3057\u307e\u305b\u3093\u3002\u300d<\/span>\u3068\u8a00\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3046\u3067\u3057\u3087\u3046\u304b\u3002\u300c FLS and CTS were derived from a sub-stock of FES1 ES cells.\u300d\u306e\u300ca sub-stock of FES1 ES cells\u300d\u304c\u7d30\u80deA\u306b\u8a72\u5f53\u3059\u308b\u308f\u3051\u3067\u3001\u304d\u3061\u3093\u3068\u56f3\u306b\u53cd\u6620\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u304c\u3053\u306e\u300cwere derived from\u300d\u3092\u7406\u89e3\u3067\u304d\u306a\u3044\u304b\u3089\u3001\u5f53\u65b9\u306f\u3082\u3068\u3088\u308aplus99%\u3055\u3093<\/a>\u3082\u6faa\u6a19\u3055\u3093<\/a>\u3082\u5b66\u3068\u307f\u5b50\u306f\u3000be \u3068\u3000be derived from \u306e\u9055\u3044\u304c\u308f\u304b\u3089\u306a\u3044\uff1d\u4e2d\u9ad8\u751f\u306e\u82f1\u8a9e\u304c\u3067\u304d\u306a\u3044\u3068\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u3059\u306d\u3002<\/p>\n

\u6faa\u6a19\u3055\u3093\u304c\u3000\u2460be \u2461be from \u2462be derived from\u3000\u306f\u610f\u5473\u304c\u7570\u306a\u308b\u3068\u5b66\u3068\u307f\u5b50\u306b\u6559\u3048\u3066\u3044\u308b\u306e\u306b\u3001\u5b66\u3068\u307f\u5b50\u306f\u2460be \u2461be from \u2462be derived from\u3000\u3067\u3001the same cell\u3000\u306e\u610f\u5473\u306b\u9055\u3044\u304c\u51fa\u307e\u305b\u3093\u3002<\/a>\u3068\u7406\u89e3\u3067\u304d\u306a\u3044\u3088\u3046\u3067\u3059\u3002\u3060\u304b\u3089\u300c\u4e2d\u9ad8\u751f\u82f1\u8a9e\u300d\u30ec\u30d9\u30eb\u306e\u82f1\u8a9e\u304c\u3067\u304d\u306a\u3044\u8a00\u308f\u308c\u3066\u3044\u308b\u306e\u306b\u5168\u304f\u7406\u89e3\u3067\u304d\u306a\u3044\u3093\u3067\u3059\u306d\u3002\u6065\u305a\u304b\u3057\u3044\u3067\u3059\u306d\u3002<\/p>\n

\u300cplus99%\u3055\u3093\u3001\u6faa\u6a19\u3055\u3093\u306e\u3088\u3046\u306a\u4e00\u822c\u4eba\u3092\u5c02\u9580\u5bb6\u306e\u3088\u3046\u306b\u6301\u3061\u4e0a\u3052\u3066\u307e\u3059\u306d\u3002\u300d<\/span>\u3000\u2190\u3000\u4e2d\u9ad8\u751f\u306e\u82f1\u8a9e\u30ec\u30d9\u30eb\u3067\u3059\u304b\u3089\u3001plus99%\u3055\u3093\u3001\u6faa\u6a19\u3055\u3093\u306f\u3082\u3068\u3088\u308a\u3001\u305d\u306e\u3078\u3093\u306e\u5927\u5b66\u751f\u306b\u805e\u3044\u3066\u3082\u540c\u3058\u7b54\u3048\u3001\u300c\u540c\u3058\u3068\u306f\u89e3\u91c8\u3067\u304d\u306a\u3044\u300d\u304c\u8fd4\u3063\u3066\u6765\u308b\u3067\u3057\u3087\u3046\u306d\u3002<\/p>\n

\u300c\u305d\u3082\u305d\u3082\u3001\u305f\u3081\u606f\u56f3\u3067\u793a\u3055\u308c\u305f\u7d30\u304b\u3044\u6570\u5024\u306e\u8fd1\u4f3c\u306f\u3001\u611f\u60f3\u3055\u3093\u305f\u3061\u304b\u3089\u3001\u201d\u7d20\u4eba\u306e\u305f\u308f\u3054\u3068\u201d\u3068\u4e00\u559d\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u300d<\/span>\u3000\u2190\u3000\u611f\u60f3\u3055\u3093\u306e\u767a\u8a00\u306e\u3042\u308bURL\u3092\u66f8\u3044\u3066\u304f\u3060\u3055\u3044\u3002\u305d\u3046\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\uff14\u6841\u306e\u6570\u5024\u3092\u793a\u3057\u305f\u306e\u3067\u3059\u304b\u3089\u300199.9%\u306899.1%\u306b\u306f\u9055\u3044\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002\u548c\u30e2\u30ac\u6c0f\u3068\u540c\u3058\u57fa\u6e96\u3067\u4f5c\u6210\u3057\u305f\u56f3\u3067\u3059\u3002
\n\u300c\u305d\u3053\u3060\u3051\u3067\u306f\u985e\u4f3c\u6027\u306e\u7cbe\u5ea6\u304c\u4f4e\u3044\u3068\u3001\u611f\u60f3\u3055\u3093\u305f\u3061\u304c\u8a00\u3063\u3066\u3044\u307e\u3057\u305f\u3002\u300d<\/span>\u3000\u2190\u3000\u611f\u60f3\u3055\u3093\u305f\u3061\u306e\u767a\u8a00\u3092\u3001\u5b66\u3068\u307f\u5b50\u306e\u8133\u5185\u3067\u306f\u306a\u304f\u3001\u793a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u300cnearly identical\u3067\u3001\u5b66\u8853\u7684\u306b\u306f\u8fd1\u3044\u6642\u70b9\u3067\u6a39\u7acb\u3055\u308c\u3066\u3044\u308b\u3068\u3044\u3046\u610f\u5473\u300d<\/span>\u3000\u2190\u3000\u9055\u3044\u307e\u3059\u3002\u3053\u306e\u6587\u7ae0\u306b\u306f\u300c\u6642\u70b9\u300d\u3068\u3044\u3046\u6642\u9593\u8ef8\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u300c\u307b\u307c\u540c\u3058\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u3001\u300c\u4e00\u81f4\u3057\u3066\u3044\u308b\u300d\u3042\u308b\u3044\u306f\u300c\u540c\u3058\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u300c\u5b66\u3068\u307f\u5b50\u306f\u3001FES1\u304b\u3089129\/GFP ES\u3078\u306f\u6642\u9593\u304c\u304b\u304b\u308b\u3068\u8a00\u3063\u3066\u3044\u304d\u307e\u3059\u3002\u6642\u9593\u304c\u304b\u304b\u3089\u306a\u3044\u3068\u8a3c\u660e\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u300d<\/span>\u3000\u2190\u3000\u5f53\u65b9\u306f\u5c02\u9580\u5bb6\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304b\u3089\u3001\u5c02\u9580\u5bb6\u306e\u610f\u898b\u306b\u5f93\u3044\u307e\u3059\u3002\u3053\u308c\u3060\u3051FES1\u304b\u3089129\/GFP ES\u304c\u4f5c\u3089\u308c\u3001\u5b9a\u91cf\u7684\u306b\u5909\u7570\u91cf\u304c\u793a\u3055\u308c\u554f\u984c\u3068\u3055\u308c\u3066\u3044\u308b\u306e\u306b\u3001\u5c02\u9580\u5bb6\u306e\u3060\u308c\u3082\u3001FES1 \u3068\u307b\u304b\u306e\uff13\u7a2e\u306e\u7d30\u80de\u306e\u9593\u306e\u5909\u7570\u91cf\u306f\u5c0f\u4fdd\u65b9\u6c0f\u7406\u7814\u6ede\u5728\u671f\u9593\u306b\u306f\u3067\u304d\u308b\u91cf\u3067\u306f\u306a\u3044\u3068\u3044\u3046\u30b3\u30e1\u30f3\u30c8\u3092\u3057\u3066\u3044\u306a\u3044\u3068\u3044\u3046\u306e\u304c\u5f53\u65b9\u306e\u6839\u62e0\u3067\u3059\u3002\u8a3c\u62e0\u306a\u3069\u51fa\u305b\u307e\u305b\u3093\u3002\u3069\u306a\u305f\u304b\u5c02\u9580\u5bb6\u304c\u3001\u3053\u306e\u671f\u9593\u3067\u306f\u3053\u308c\u307b\u3069\u306e\u5909\u7570\u3057\u306a\u3044\u3068\u3044\u3046\u306e\u306a\u3089\u3001\u305d\u308c\u306b\u5f93\u3044\u307e\u3059\u3002\u5b66\u3068\u307f\u5b50\u306f\u5c02\u9580\u5bb6\u306e\u610f\u898b\u3092\u805e\u3044\u3066\u304d\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u300c\u5b66\u3068\u307f\u5b50\u8aac\u306a\u3093\u3066\u7c21\u5358\u306a\u3093\u3060\u304b\u3089\u300d<\/span>\u3000\u2190\u3000\u3060\u3063\u305f\u3089\u5b66\u3068\u307f\u5b50\u304c\u4f5c\u56f3\u3057\u3066\u307f\u3066\u304f\u3060\u3055\u3044\u3002\u624b\u66f8\u304d\u3067\u30b9\u30de\u30db\u3067\u64ae\u5f71\u3057\u3066\u30a2\u30c3\u30d7\u3059\u308c\u3070\u3044\u3044\u3067\u3057\u3087\u3002\u3067\u304d\u306a\u3044\u306e\uff1f<\/p>\n

\u300c\u305f\u3081\u606f\u3055\u3093\u306f\u3001\u4f55\u306e\u610f\u5473\u3082\u306a\u3044\u3001\u4f55\u3092\u793a\u5506\u3059\u308b\u3067\u3082\u306a\u3044\uff21\uff22\uff23\u306a\u308b\u7d30\u80de\u3092\u51fa\u3057\u3066\u3001\u7269\u4e8b\u3092\u8907\u96d1\u5316\u3057\u3066\u3044\u308b\u3060\u3051\u3058\u3083\u306a\u3044\u3067\u3059\u304b\uff1f
\n\u300d<\/span>\u3000\u2190\u3000\u3000\u308f\u304b\u308a\u3084\u3059\u3044\u304b\u3089\u5b66\u3068\u307f\u5b50\u304c\u89e3\u8aac<\/a>\u3057\u305f\u3093\u3067\u3057\u3087\uff1f\u9055\u3046\u306e\uff1f\u548c\u30e2\u30ac\u6c0f\u306e\u56f3\u306b\u306f\u300c\u7d30\u80deA\u300d\u306f\u306a\u3044\u3067\u3059\u3088\u3002<\/p>\n

129\/GFP ES\u3000FLS\u3001CTS\u306f\u3001\u540c\u4e00\u7d30\u80de\u3068\u3044\u3046\u3088\u308a\u3001\u3053\u306e\u4e09\u8005\u306f\u3001\u77ed\u671f\u9593\u5185\u306b\u540c\u3058\u7d30\u80de\u304b\u3089\u4f5c\u3089\u308c\u305f\u7d30\u80de\u3067\u3059\u3002
\n\u305f\u3068\u3048\u3070\u3001\u548c\u30e2\u30ac\u6c0f\u306e\u56f3\u3067\u8a00\u3048\u3070\u3001FES1\u304b\u3089\u6642\u9593\u304c\u304b\u304b\u3063\u3066\u7d30\u80deA\u306b\u306a\u308a\u3001\u3053\u3053\u304b\u3089\u305d\u308c\u305e\u308c\u8fd1\u3044\u6642\u70b9\u3067\u3001129\/GFP ES\u3000FLS\u3001CTS\u306b\u306a\u3063\u3066\u307e\u3059\u3002
\nFES1\u304b\u3089\u4f55\u5ea6\u3082\u57f9\u990a\u304c\u7e70\u308a\u8fd4\u3055\u308c\u3001129\/GFP ES\u3000FLS\u3001CTS\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p><\/blockquote>\n

\u3068\u89e3\u8aac\u3057\u305f\u306e\u306f\u5b66\u3068\u307f\u5b50\u3067\u3059\u3088\u3002\u5f53\u65b9\u306e\u56f3\u3092\u898b\u3066\u7406\u89e3\u3057\u3066\u66f8\u3044\u305f\u306e\u3067\u3057\u3087\u3002\u548c\u30e2\u30ac\u6c0f\u306e\u56f3\u3092\u89e3\u8aac\u3057\u305f\u3068\u3044\u3046\u306e\u306a\u3089\u3001\u305d\u306e\u56f3\u306e\u3042\u308bURL\u3092\u793a\u3057\u3066\u3061\u3087\u3046\u3060\u3044\u3002<\/p>\n

\u300c\u3000\u3044\u3044\u3048\u3001\u308f\u304b\u308a\u307e\u305b\u3093\u306d\u3002\u4f55\u306e\u7406\u89e3\u306b\u3082\u3064\u306a\u304c\u308a\u307e\u305b\u3093\u3002\u300d<\/span>\u3000\u2190\u3000\u7406\u89e3\u3057\u305f\u304b\u3089\u3001\u548c\u30e2\u30ac\u6c0f\u306e\u4f5c\u6210\u3057\u305f\u56f3\u3068\u8aa4\u89e3\u3057\u305f\u304b\u3089\u3001\u89e3\u8aac\u3057\u305f\u306e\u3067\u3057\u3087\u3046\u304c\u3002\u3053\u306e\u5b66\u3068\u307f\u5b50\u306b\u3068\u3063\u3066\u6065\u305a\u304b\u3057\u3044\u4e8b\u4ef6\u3092\u4f55\u56de\u3082\u6301\u3061\u51fa\u3057\u3066\u3044\u308b\u306e\u306f\u5f53\u65b9\u3067\u306f\u306a\u3044\u3067\u3059\u3088\u3002\u5b66\u3068\u307f\u5b50\u81ea\u8eab\u3067\u3059\u3088\u3002<\/p>\n

\u300c\u305f\u3081\u606f\u3055\u3093\u306f\u3001\u5fc3\u96fb\u56f3\u3084\u80ba\u6a5f\u80fd\u306e\u8aac\u660e\u306b\u7aae\u3057\u305f\u6642\u306b\u3001\u81ea\u3089\u3001\u610f\u5473\u306e\u306a\u3044\u56f3\u5f0f\u5316\u3092\u3057\u3066\u3001\u81ea\u5206\u81ea\u8eab\u3092\u7406\u89e3\u3055\u305b\u3066\u304d\u305f\u306e\u3067\u306f\u306a\u3044\u3067\u3059\u304b\uff1f\u300d<\/span>\u3000\u2190\u3000\u3000\u306f\u3042\uff1f\u306a\u3093\u306e\u3053\u3068\u3067\u3057\u3087\u3002\u3069\u3053\u306b\u5f53\u65b9\u304c\u8aac\u660e\u306b\u7aae\u3057\u305f\u3068\u304d\u306e\u56f3\u304c\u3042\u308b\u3093\u3067\u3057\u3087\uff1f\u5b66\u3068\u307f\u5b50\u306e\u5984\u60f3\u8133\u5185\u306f\u3060\u308c\u3082\u8997\u3051\u306a\u3044\u306e\u3060\u304b\u3089\u3001\u305d\u306e\u5f53\u65b9\u306e\u8aac\u660e\u306b\u7aae\u3057\u305f\u56f3\u3068\u3084\u3089\u3092\u793a\u3057\u3066\u9802\u6234\u3002<\/p>\n

\u300c\u4e8b\u6545\u8aac\u306f\u3001\u7814\u7a76\u8005\u306e\u8ab0\u3082\u3001\u30ad\u30e3\u30ea\u30a2\u304c\u7d9a\u3051\u3089\u308c\u306a\u304f\u306a\u308b\u7a0b\u306e\u81f4\u547d\u7684\u50b7\u306b\u306a\u3089\u306a\u3044\u3067\u6e08\u307f\u307e\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u5fa1\u5197\u8ac7\u3092\u3002\u30a4\u30f3\u30c1\u30ad\u8ad6\u6587\u3092\u4f5c\u3063\u305f\u308f\u3051\u3067\u3059\u304b\u3089\u3001\u8457\u8005\u306b\u3068\u3063\u3066\u306f\u3001\u305d\u306e\u539f\u56e0\u304c\u3069\u3053\u306b\u3042\u308b\u304b\u3068\u306f\u95a2\u4fc2\u306a\u304f\u3001\u81f4\u547d\u50b7\u3067\u3059\u3002\u539f\u56e0\u306b\u3088\u3063\u3066\u81f4\u547d\u50b7\u306b\u306a\u308b\u304b\u306a\u3089\u306a\u3044\u304b\u3068\u3044\u3046\u30ec\u30d9\u30eb\u306b\u306fSTAP\u4e8b\u4ef6\u306f\u306a\u3044\u306e\u304c\u308f\u304b\u3089\u306a\u3044\u306e\uff1f\u547d\u3092\u843d\u3068\u3057\u305f\u65b9\u304c\u3044\u308b\u3093\u3067\u3059\u3088\u3002\u3069\u3046\u3057\u3066\u3053\u3093\u306a\u60b2\u5287\u306b\u306a\u3063\u305f\u3093\u3067\u3057\u3087\u3002\u5b66\u3068\u307f\u5b50\u306f\u4f55\u3082\u8003\u3048\u3066\u306a\u3044\u306e\u3067\u3059\u304b\uff1f<\/p>\n

\u300c\u4e8b\u6545\u8aac\u306f\u4e00\u756a\u3001\u8aac\u5f97\u529b\u304c\u3042\u308b\u306e\u3067\u3059\u3002\u300d<\/span>\u3000\u2190\u3000\u5b66\u3068\u307f\u5b50\u306f\u6839\u62e0\u3092\u793a\u3055\u306a\u3044\u304b\u3089\u5168\u304f\u8aac\u5f97\u529b\u304c\u306a\u3044\u306e\u3067\u3059\u3088\u3002\u305d\u308c\u304c\u8a3c\u62e0\u306b\u8ab0\u3082\u5b66\u3068\u307f\u5b50\u3092\u652f\u6301\u3057\u3066\u3044\u306a\u3044<\/span>\u3067\u306f\u306a\u3044\u3067\u3059\u304b\u3002\u81ea\u5206\u3067\u81ea\u5206\u3092\u7d0d\u5f97\u3055\u305b\u3066\u3069\u3046\u3059\u308b\u306e\uff1f\u73fe\u5b9f\u3092\u898b\u3064\u3081\u3066\u3054\u89a7\u3002<\/p>\n

\u300c\u8ab0\u304c\u4f55\u306e\u76ee\u7684\u3067FES1\u3092\u89e3\u51cd\u30fb\u57f9\u990a\u3092\u7d9a\u3051\u3066\u3044\u305f\u304b\uff1f\uff5d\u306f\u3001\u305f\u3081\u606f\u3055\u3093\u81ea\u8eab\u3067\u8003\u3048\u3066\u304f\u3060\u3055\u3044\u3002\u300d<\/span>\u3000\u2190\u3000ES\u7d30\u80de\u304c\u6b32\u3057\u304b\u3063\u305f\u304b\u3089\u3067\u3059\u3002\u5b66\u3068\u307f\u5b50\u306f\u3001\u3069\u3093\u306a\u65b9\u304c\u4f55\u6545FES1\u3092\u89e3\u51cd\u3057\u57f9\u990a\u3057\u7d9a\u3051\u305f\u3068\u3044\u3046\u306e\u3067\u3057\u3087\u3046\u304b\uff1f
\n\"\"<\/a>
\n\u3055\u304f\u3089\uff08\u30bd\u30e1\u30a4\u30e8\u30b7\u30ce\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

\u5f53\u65b9\u7b49\u304c\u3001\u5b66\u3068\u307f\u5b50\u306e\u82f1\u8a9e\u306e\u89e3\u91c8\u304c\u9593\u9055\u3044\u3060\u3068\u3044\u3063\u305f\u3089\u3001\u305f\u3081\u606f\u3055\u3093\u306f\u81ea\u8eab\u306e\u6b63\u5f53\u6027\u3092\u4e3b\u5f35\u3059\u308b\u6642\u306f\u3001\u3044\u3064\u3082\u4e2d\u9ad8\u751f\u82f1\u8a9e\u306e\u77e5\u8b58\u3092\u6301\u3061\u51fa\u3057\u307e\u3059\u3002\u60c5\u3051\u306a\u3044\u3067\u3059\u306d\u3002\u3068\u306e\u3053\u3068\u3067\u3059\u3002however\u3001 therefore\u3001 among\u3001 exc … \u7d9a\u304d\u3092\u8aad\u3080 \u4e2d\u9ad8\u751f\u82f1\u8a9e…\u60c5\u3051\u306a\u3044\u3067\u3059\u306d<\/span> →<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,8],"tags":[],"class_list":["post-23989","post","type-post","status-publish","format-standard","hentry","category-education","category-fake"],"_links":{"self":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/23989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23989"}],"version-history":[{"count":27,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/23989\/revisions"}],"predecessor-version":[{"id":24032,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=\/wp\/v2\/posts\/23989\/revisions\/24032"}],"wp:attachment":[{"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nbsigh2.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}