{"id":17039,"date":"2020-02-15T12:18:09","date_gmt":"2020-02-15T03:18:09","guid":{"rendered":"http:\/\/seigi.accsnet.ne.jp\/sigh\/blog\/?p=17039"},"modified":"2021-12-17T14:34:25","modified_gmt":"2021-12-17T05:34:25","slug":"%e5%85%a8%e9%9d%a2%e6%95%97%e5%8c%97%e3%81%ae%e3%81%8f%e3%81%9b%e3%81%ab","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=17039","title":{"rendered":"\u5168\u9762\u6557\u5317\u306e\u304f\u305b\u306b"},"content":{"rendered":"

\u5b66\u3068\u307f\u5b50\u306f\u7d76\u5bfe\u8a8d\u3081\u306a\u3044\u3067\u3057\u3087\u3046\u3051\u3069\u3001\u4eca\u56de\u306e\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306e\u4ef6\u306f\u3001\u5b66\u3068\u307f\u5b50\u306e\u5168\u9762\u6557\u5317\u306a\u306e\u306f\u3001\u300c\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u306b\u304a\u3051\u308b\u3001\u53d7\u5bb9\u4f53\u306e\u8003\u3048\u65b9\u306f\u73fe\u5728\u3001\u89e3\u660e\u304c\u9032\u884c\u4e2d\u306e\u77e5\u8b58\u5206\u91ce\u3067\u3059\u3002<\/a>\u300d \u3092\u8aad\u3081\u3070\u660e\u767d\u3067\u3059\u3002\u5225\u306b\u52dd\u6557\u3092\u7af6\u3063\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u306d\u3002<\/p>\n

\u5f53\u65b9\u7b49\u304cACE2\u53d7\u5bb9\u4f53\u306a\u308b\u7269\u306f\u5b58\u5728\u3057\u306a\u3044\u3068\u3044\u3046\u4e3b\u5f35\u306b\u5bfe\u3057\u3001\u7b54\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u304b\u3089\u3067\u3059\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u300c\u7814\u7a76\u8005\u5c64\u304c\u3001\u81e8\u5e8a\u5bb6\u3092\u653b\u6483\u3057\u3066\u3082\u610f\u5473\u306a\u3044\u300d\u300c\u305f\u3081\u606f\u30d6\u30ed\u30b0\u306e\u4eba\u305f\u3061\u306f\u3001\u5b66\u3068\u307f\u5b50\u3068\u8208\u5473\u306e\u5bfe\u8c61\u304c\u9055\u3046\u3057\u3001\u5927\u4e8b\u306a\u3068\u3053\u308d\u3067\u5b66\u3068\u307f\u5b50\u3092\u653b\u3081\u5207\u308c\u3066\u3044\u306a\u3044\u3002\u300d\u300c\u7d30\u304b\u3044\u7528\u8a9e\u306b\u3053\u3060\u308f\u3063\u3066\u3082\u3001\u5927\u304d\u306a\u898b\u843d\u3068\u3057\u3092\u3059\u308c\u3070\u3001\u30d6\u30ed\u30b0\u8aad\u8005\u306b\u306f\u5370\u8c61\u304c\u60aa\u3044\u3002
\n\u91cd\u7bb1\u306e\u9685\u3092\u3064\u3064\u3044\u3066\u3044\u308b\u3068\u306e\u5370\u8c61\u3092\u8aad\u307f\u624b\u306b\u4e0e\u3048\u308b\u3002\u300d
\n\u306a\u3069\u3068\u90fd\u5408\u306e\u3044\u3044\u3088\u3046\u306a\u30bb\u30ea\u30d5\u3092\u308f\u3081\u3044\u3066\u3044\u307e\u3059\u304c\u3001ACE2\u53d7\u5bb9\u4f53\u3068\u304b\u7d30\u80de\u53d7\u5bb9\u4f53\u306a\u3069\u3068\u3044\u3046\u3042\u308a\u3082\u3057\u306a\u3044\u7269\u3092\u4f5c\u308a\u51fa\u3057\u3001\u3053\u308c\u3089\u306f\u5b58\u5728\u3057\u306a\u3044\u3068\u3044\u3046\u30af\u30ec\u30fc\u30e0\u306b\u5bfe\u3057\u306a\u306b\u3082\u7b54\u3048\u3089\u308c\u306a\u3044\u306e\u306f\u3001\u5168\u9762\u6557\u5317\u3068\u3060\u308c\u3082\u304c\u8a8d\u8b58\u3059\u308b\u3068\u3053\u308d\u3067\u3059\u304c\u3001\u5b66\u3068\u307f\u5b50\u3060\u3051\u306f\u5426\u5b9a\u3059\u308b\u3067\u3057\u3087\u3046\u306d\u3002<\/p>\n

\u300c\u7d30\u80de\u53d7\u5bb9\u4f53\u306f\u3001\u610f\u5473\u304c\u901a\u3058\u308b\u8a00\u8449\u3067\u3059\u3002\u305f\u3081\u606f\u3055\u3093\u3092\u9664\u304d\u3001\u5fc5\u8981\u304c\u3042\u308c\u3070\u3001\u7d30\u80de\u53d7\u5bb9\u4f53\u306a\u308b\u8a00\u8449\u3092\u4f7f\u3046\u4eba\u306f\u3044\u307e\u3059\u3002\u300d
\n\u306f\u8fd4\u4e8b\u3067\u306f\u306a\u3044\u3088\u3002\u300c\u7d30\u80de\u53d7\u5bb9\u4f53\u300d\u306e\u610f\u5473\u304c\u308f\u304b\u308b\u65b9\u306f\u8ab0\uff1f\u610f\u5473\u304c\u901a\u3058\u308b\u3068\u3059\u308b\u4eba\u3092\u3001\u5c02\u9580\u66f8\u304c\u3042\u308b\u3068\u3059\u308b\u306e\u3060\u304b\u3089\u4f7f\u3046\u5c02\u9580\u5bb6\u3092\u63a2\u3057\u51fa\u3057\u3066\u304b\u3089\u8a00\u3048\u3002<\/p>\n

\u306a\u306b\u3057\u308d\u3001\u5f53\u65b9\u7b49\u306f\u4f55\u3082\u77e5\u3089\u306a\u3044\u30c9\u7d20\u4eba\u3001\u5b66\u3068\u307f\u5b50\u306f\u4f55\u3067\u3082\u3057\u3066\u3044\u308b\u81e8\u5e8a\u5bb6\u3067\u3059\u304b\u3089\u306d\u3002<\/p>\n

\u3057\u3064\u3053\u3044\u3051\u3069\u300cACE2\u53d7\u5bb9\u4f53\u300d\u306a\u308b\u7269\u3092\u3001\u305d\u3057\u3066\u300c\u7d30\u80de\u53d7\u5bb9\u4f53\u300d\u306a\u308b\u7269\u306e
\n\u5b58\u5728\u3092\u3001\u793a\u3081\u305b\u3002\u9593\u9055\u3044\u3060\u3063\u305f\u3089\u9593\u9055\u3044\u3068\u8a8d\u3081\u3066\u8a02\u6b63\u3057\u308d\u3002<\/p>\n

\u8a00\u8449\u5c3b\u3092\u6349\u3048\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3059\u3088\u3002\u91cd\u7bb1\u306e\u89d2\u3092\u3064\u3064\u3044\u3066\u3044\u308b\u306e\u3067\u306f\u306a\u3044\u3067\u3059\u3088\u3002\u305d\u306e\u3088\u3046\u306a\u3042\u308a\u3082\u3057\u306a\u3044\u7269\u3067\u89e3\u8aac\u306a\u3093\u304b\u3057\u3066\u3044\u308b\u304b\u3089\u3001\u8aa4\u308a\u306f\u8aa4\u308a\u3060\u3068\u6307\u6458\u3057\u3066\u3044\u308b\u3093\u3067\u3059\u3088\u3002<\/p>\n

\u300cACE\uff12\u306f\u3001\u4ee5\u4e0b\u306e\u30a6\u30a4\u30ad\u30da\u30c7\u30a3\u30a2\u82f1\u6587\u89e3\u8aac\u3067\u306f\u3001\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3II\u3092\u5206\u89e3\u3057\u3066\u3001nonapeptide angiotensin[1-9]\u3078\u306e\u4f5c\u7528\u3092\u793a\u3059\u3002<\/a>\u300d\uff08\u9b5a\u62d3<\/a>\uff09\u306a\u3093\u3066\u82f1\u8a9e\u7248\u306eWiKi\u306e\u6587\u3092\u3067\u305f\u3089\u3081\u7ffb\u8a33\u3092\u3055\u3063\u3055\u3068\u8a02\u6b63\u3057\u305f\u3089\uff1f\u533b\u5e2b\u3068\u3057\u3066\u6065\u305a\u304b\u3057\u304f\u306a\u3044\u306e\uff1f
\nACE\uff12\u306f\u30a2\u30df\u30ce\u9178\uff11\u30b1\u3092\u53d6\u308a\u9664\u304f\u304f\u3053\u3068\u306b\u3088\u3063\u3066\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3I\u304b\u3089angiotensin[1-9]\u3042\u308b\u3044\u306f\u30a2\u30f3\u30ae\u30aa\u30c6\u30f3\u30b7\u30f3II\u304b\u3089angiotensin[1-7]\u3092\u4f5c\u308b\u306e\u3060\u3002\u304d\u3061\u3093\u3068WiKi\u3092\u8aad\u3081\u3002\u3066\u8aad\u3081\u306a\u3044\u306e\u304b\u3002<\/p>\n

\u300c\u30cf\u30f3\u30cb\u30d0\u30eb\u30fb\u30d5\u30a9\u30fc\u30c1\u30e5\u30f3\u3055\u3093\u3068\u306e\u8b70\u8ad6\u306f\u3001\u4e0d\u6bdb\u300d
\n\u305d\u3046\u3067\u3057\u3087\u3046\u306d\u3002\u53cd\u8ad6\u3067\u304d\u306a\u3044\u304b\u3089\u306a\u3002
\n\u300c\u3084\u3063\u3071\u308a\u3055\u3093\u3068\u306e\u7d4c\u7def\u3082\u3001\u305f\u3081\u606f\u3055\u3093\u304c\u7406\u89e3\u3059\u308b\u306e\u306f\u96e3\u3057\u3044\u300d
\n\u305d\u3046\u3067\u3057\u3087\u3046\u306d\u3002yap*ari*w*katt*na*\u3055\u3093\u304c\u8a00\u3044\u3082\u3057\u306a\u3044\u3053\u3068\u3092\u4f55\u6545\u5b66\u3068\u307f\u5b50\u306f\u8a00\u3063\u305f\u3068\u4e3b\u5f35\u306e\u304b\u306f\u7406\u89e3\u3067\u304d\u306a\u3044\u3067\u3059\u306a\u3002<\/p>\n

\u5b66\u3068\u307f\u5b50\u306e\u3053\u308c\u307e\u3067\u306e\u5984\u60f3\u3092\u307e\u3068\u3081\u3066\u307f\u307e\u3057\u305f\u3002\u5b66\u3068\u307f\u5b50\u306f\u9055\u3046\u3068\u3044\u3046\u3067\u3057\u3087\u3046\u3051\u3069\u3001\u5b66\u3068\u307f\u5b50\u306e\u3053\u308c\u307e\u3067\u306e\u767a\u8a00\u3092\u898b\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u3060\u3063\u305f\u3053\u3068\u304c\u63a8\u6e2c\u3067\u304d\u307e\u3059\u3002
\n##########################
\n\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u306f\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff12\u306b\u7d50\u5408\u3059\u308b\u3089\u3057\u3044\u3002
\n\u2193
\n\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u3068\u306f\u8840\u5727\u8abf\u7bc0\u6a5f\u69cb\u3092\u53d7\u3051\u6301\u3064\u30db\u30eb\u30e2\u30f3\u3060
\n\u2193
\n\u3060\u304b\u3089\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u963b\u5bb3\u85ac\u3084\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u306f\u964d\u5727\u5264\u3060\u3001\u8af8\u541b\u3001\u77e5\u3063\u3066\u3044\u308b\u304b\u306d\u3002\u81e8\u5e8a\u5bb6\u306e\u5e38\u8b58\u306a\u306e\u3060\uff08\u3053\u3053\u3067\u3053\u308c\u3089\u306e\u85ac\u7269\u7b49\u3092\u6b63\u3057\u304f\u5f15\u7528\u3067\u304d\u306a\u304b\u3063\u305f\u306e\u3067\u7686\u3055\u3093\u306b\u99ac\u9e7f\u306b\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u308c\u3067\u3082\u533b\u8005\u304b\u3088\u3068\u3002\u3067\u3082\u30ea\u30f3\u30af\u5148\u306f\u9593\u9055\u3044\u304c\u306a\u3044\u3068\u8a00\u3044\u5f35\u308b\u3082\u306e\u3067\u3001\u5931\u7b11\u3092\u3055\u3089\u306b\u8cb7\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\uff09
\n\u2193
\n\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\u304c\u30a6\u30a4\u30eb\u30b9\u306e\u53d7\u5bb9\u4f53\u3060
\n\u2193
\n\u3057\u304b\u3057\u3001\u307e\u3066\u3088\u3001\u4e2d\u56fd\u4eba\u306e\u66f8\u3044\u305f\u8ad6\u6587\u306b\u300cangiotensin-converting enzyme 2 receptor\u300d\u3068\u3042\u3063\u305f\u3002\u3069\u3046\u3084\u3089ACE2\u3092\u53d7\u5bb9\u3059\u308b\u7269\u8cea–ACE2\u53d7\u5bb9\u4f53–\u306a\u308b\u7d30\u80de\u819c\u306b\u767a\u73fe\u3059\u308b\u7269\u8cea\u304c\u3042\u308b\u3089\u3057\u3044\u3002\u3053\u308c\u306f\u7d30\u80de\u53d7\u5bb9\u4f53\u306e\u4e00\u3064\u3060\u3002(\u3053\u306e\u82f1\u8a9e\u306e\u89e3\u91c8\u304c\u81f4\u547d\u7684\u3060\u3063\u305f\u306e\u3067\u3059\u3002\u3053\u306e\u8ad6\u6587\u3092\u982d\u304b\u3089\u8aad\u3081\u3070ACE2\u53d7\u5bb9\u4f53\u306a\u308b\u3082\u306f\u306a\u3044\u306e\u304c\u308f\u304b\u308a\u307e\u3059\u3002\u4e00\u90e8\u3092\u8aa4\u8aad\u3057\u3066\u8ad6\u3092\u5f35\u308b\u5b66\u3068\u307f\u5b50\u306e\u7279\u5fb4\u304c\u51fa\u3066\u3044\u307e\u3059)
\n\u2193
\n\u7d30\u80de\u819c\u306b\u767a\u73fe\u3059\u308b\u53d7\u5bb9\u4f53\uff08\u30bf\u30f3\u30d1\u30af\uff09\u3068\u3044\u3048\u3070G\u30bf\u30f3\u30d1\u30af\u8cea\u5171\u5f79\u578b\u53d7\u5bb9\u4f53\u306e\u3088\u3046\u306b\u7d30\u80de\u5185\u3078\u60c5\u5831\u3092\u4f1d\u3048\u308b\u4ed5\u7d44\u307f\u3092\u62c5\u3046\u7269\u8cea\u3060\u3002\u3060\u304b\u3089ACE\uff08\uff12\uff09\u53d7\u5bb9\u4f53\u3082\u7d30\u80de\u5185\u60c5\u5831\u4f1d\u9054\u6a5f\u80fd\u304c\u3042\u308b\u306e\u3060\u308d\u3046\u3002\uff08\u819c\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u30bf\u30f3\u30d1\u30af\u306e\u4e2d\u9014\u534a\u7aef\u306a\u77e5\u8b58\u304c\u707d\u3044\u3057\u307e\u3057\u305f\u3002\u305d\u3093\u306a\u3053\u3068\u306f\u8ad6\u6587\u7b49\u306e\u3069\u3053\u306b\u3082\u3001WiKi\u306b\u3067\u3059\u3089\u66f8\u3044\u3066\u3042\u308a\u307e\u305b\u3093\uff09
\n\u2193
\n\u6b63\u5e38\u3067\u306f\u306fACE2\u306b\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u304c\u7d50\u5408\u3057\u3001\u3053\u306e\u8907\u5408\u4f53\u304c\u7d30\u80de\u819c\u306b\u3042\u308bACE2\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3066\u7d30\u80de\u5185\u306b\u60c5\u5831\u3092\u4f1d\u9054\u3059\u308b\u3002\u3057\u304b\u3057\u30a6\u30a4\u30eb\u30b9\u306fACE2\u306b\u7d50\u5408\u3057\u3053\u306e\u8907\u5408\u4f53\u306fACE2\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3066\u3082\u7d30\u80de\u5185\u60c5\u5831\u4f1d\u9054\u3092\u884c\u308f\u306a\u3044\u3001\u3059\u306a\u308f\u3061\u60c5\u5831\u4f1d\u9054\u3092\u963b\u5bb3\u3059\u308b\u3002\u3053\u306e\u3053\u3068\u304c\u8840\u5727\u8abf\u7bc0\u306b\u30a6\u30a4\u30eb\u30b9\u304c\u60aa\u3055\u3092\u3059\u308b\u3053\u3068\u306a\u306e\u304b\u3082\u3057\u308c\u306a\u3044\u3002
\n\u300c\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u75c7\u304c\u3001\u4eba\u306e\u8840\u5727\u8abf\u7bc0\u6a5f\u80fd\u306e\u53d7\u5bb9\u4f53\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u306f\u3001\u4eca\u5f8c\u3082\u6ce8\u76ee\u3060\u308d\u3046\u3002\u300d\u306f\u5b66\u3068\u307f\u5b50\u306e\u5148\u898b\u306b\u6e80\u3061\u305f\u3059\u3070\u3089\u3057\u3044\uff48\u767a\u8a00\u306a\u306e\u3060\u3002\u305f\u3081\u606f\u306e\u7d20\u4eba\u8af8\u541b\u3001\u81e8\u5e8a\u5bb6\u306e\u6b63\u3057\u3044\u7d20\u6674\u3089\u3057\u3044\u610f\u898b\u3092\u805e\u304d\u7d66\u3048\u3002
\n\u2193
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\n##############################\t\t<\/p>\n","protected":false},"excerpt":{"rendered":"

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