{"id":16216,"date":"2019-08-22T13:08:54","date_gmt":"2019-08-22T04:08:54","guid":{"rendered":"http:\/\/seigi.accsnet.ne.jp\/sigh\/blog\/?p=16216"},"modified":"2021-12-26T14:50:08","modified_gmt":"2021-12-26T05:50:08","slug":"%e5%ad%a6%e3%81%a8%e3%81%bf%e5%ad%90%e3%81%ae%e7%a7%91%e5%ad%a6%e3%81%a8%e3%81%af%e3%81%aa%e3%82%93%e3%81%a0%e3%82%8d%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/nbsigh2.com\/?p=16216","title":{"rendered":"\u5b66\u3068\u307f\u5b50\u306e\u79d1\u5b66\u3068\u306f\u306a\u3093\u3060\u308d\uff1f"},"content":{"rendered":"

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\n\u6700\u8fd1\u306e\uff15\u3064\u306e\u8a18\u4e8b\u306e\u30bf\u30a4\u30c8\u30eb\u306f
\n– \u4f55\u304b\u3001\u5225\u306e\u65b0\u3057\u3044\u5b9f\u9a13\u3092\u3001\u82e5\u5c71\u3055\u3093\u306f\u3057\u3066\u3044\u305f\u306e\u3067\u306f\u306a\u3044\u304b\uff1f\u3068<\/a>
\n– \u305f\u3081\u606f\u30d6\u30ed\u30b0\u30b9\u30bf\u30c3\u30d5\u306e\u7dcf\u653b\u6483\u3000\u7d50\u5c40\u9032\u5316\u3057\u305f\u306e\u306fplus\u3055\u3093\u3067\u3057\u305f\u3002<\/a>
\n– \u4f53\u5185\u3055\u3093\u3001\u3082\u3046\u5c11\u3057\u5927\u4eba\u306b\u306a\u308a\u307e\u3057\u3087\u3046\u3002<\/a>
\n– \u7d50\u8ad6\u3042\u308a\u304d\u30d6\u30ed\u30b0\u306b\u304a\u3051\u308b\u3001L\u3055\u3093\u3078\u306e\u898b\u89e3\u3067\u3059\u3002<\/a>
\n– \u6842\u5831\u544a\u66f8\u3068BCA\u8ad6\u6587\u9593\u306e\u5dee\u7570\u306b\u3064\u3044\u3066<\/a>
\n\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002
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\n\u300c\u4f55\u304b\u3001\u5225\u306e\u65b0\u3057\u3044…\u300d\u306f\u3001\u5f53\u65b9\u306b\u5bfe\u3059\u308b\u6279\u5224\u3068\u3001\u6842\u59d4\u54e1\u4f1a\u8a18\u8005\u4f1a\u898b\u306e\u4f0a\u85e4\u6c0f\u306e\u767a\u8a00\u3001\u305d\u3057\u3066\u5f53\u65b9\u306e\u30d6\u30ed\u30b0\u30b3\u30e1\u30f3\u30c6\u30fc\u30bf\u3078\u306e\u6279\u5224\u3067\u3059\u3002\u82e5\u5c71\u6c0f\u306b\u3064\u3044\u3066\u306f\uff11\u884c\u66f8\u3044\u3066\u3042\u308b\u3060\u3051\u3067\u3059\u3001\u79d1\u5b66\u306f\u306a\u3044\u3067\u3059\u3002
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\n\u305d\u3057\u3066\u3001\u4f8b\u306b\u3088\u3063\u3066\u7406\u7814\u5185\u90e8\u306e\u6d3e\u95a5\u304c\u3042\u3063\u3066\u300c\u6570\u306e\u591a\u3044\u4e00\u822c\u4e2d\u9593\u5c64\u306e\u610f\u5411\u304c\u3001\u6842\u5831\u544a\u66f8\u306b\u5f71\u97ff\u529b\u3092\u6301\u3063\u305f\u69d8\u76f8\u304c\u4f3a\u3048\u308b\u3002\u300d\u306a\u3069\u3068\u6839\u62e0\u306a\u304f\u767a\u8a00\u3057\u3066\u3044\u3066\u79d1\u5b66\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002
\n\u300c129B6F1ES1\u304c\u3001\u4f5c\u6210\u6642\u671f\u3001\u89aa\u30de\u30a6\u30b9\u304c\u9055\u3063\u305f\u3068\u3057\u3066\u3082\u3001AC129\u3001FLS-T1\u306e\uff14Del 1Dup\u304c\u5b8c\u5168\u306b\u4e00\u81f4\u3057\u3066\u3057\u307e\u3046\u3002\u3053\u308c\u3092\u898b\u308b\u3068\u3001Del \u3084Dup\u306e\u4e00\u81f4\u3067\u306f\u3001ES\u3068\u5e79\u7d30\u80de\u306e\u540c\u4e00\u6027\u306f\u8a3c\u660e\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u308f\u304b\u308b\u3002\u300d\u3068\u3044\u3046\u306e\u304c\u552f\u4e00\u306e\u79d1\u5b66\u7684\u8b70\u8ad6\u306a\u306e\u304b\u3082\u3057\u308c\u306a\u3044\u304c\u3001\u300c\u4f5c\u6210\u6642\u671f\u3001\u89aa\u30de\u30a6\u30b9\u304c\u9055\u3063\u305f\u3068\u3057\u3066\u3082\u3001\u300d\u306e\u610f\u5473\u306f\u306a\u3093\u3060\u308d\uff1f\u4f55\u6545\u3001\u6842\u8abf\u67fb\u59d4\u54e1\u4f1a\u306e\u7d50\u8ad6\u304c\u30ab\u30c4\u30e9\u5831\u544a\u66f8\u3055\u3093\u306e\u6307\u6458\u3067\u3072\u3063\u304f\u308a\u8fd4\u308b\u306e\u304b\u306e\u8aac\u660e\u306f\u306a\u3044\u308f\u3051\u3067\u3059\u3002
\n\u305d\u3057\u3066\u3001\u6700\u5f8c\u306e\u3042\u305f\u308a\u3067\u3001\u3044\u3088\u3044\u3088\u300c\u6842\u5831\u544a\u66f8\u3092\u8aad\u3093\u3060\u5f8c\u3001BCA\u8ad6\u6587\u3092\u8aad\u3080\u3068\u3001\u6842\u5831\u544a\u66f8\u306b\u7591\u7fa9\u3092\u611f\u3058\u308b\u3088\u3046\u306b\u306a\u308b\u3002\u305d\u306e\u90e8\u5206\u306b\u5149\u3092\u3042\u3066\u3066\u307f\u3088\u3046\u3002\u6bd4\u8f03\u3059\u308b\u3068\u3001\u3044\u308d\u3044\u308d\u308f\u304b\u3063\u3066\u304f\u308b\u3053\u3068\u304c\u3042\u308b\u3002\u300d\u3068\u671f\u5f85\u3067\u304d\u305d\u3046\u306a\u6587\u304c\u3042\u308b\u306e\u3060\u304c\u3001\u5b9f\u306f\u4ee5\u964d\u306a\u306b\u3082\u6bd4\u8f03\u3057\u3066\u3044\u306a\u3044\u3002
\n\u300cSNP\u304b\u3089\u7d30\u80de\u306e\u540c\u4e00\u6027\u3092\u6c7a\u3081\u308b\u305f\u3081\u306b\u306f\u3001NGS\u304c\u5fc5\u8981\u306b\u306a\u308b\u4e8b\u3092\u793a\u3059\u3082\u306e\u3067\u3042\u308b\u3002\u300d\u306a\u3069\u3068\u610f\u5473\u4e0d\u660e\u306a\u6587\u3092\u66f8\u3044\u3066\u306f\u3044\u308b\u3082\u306e\u306e\u3001\u6bd4\u8f03\u3057\u3066\u3044\u308b\u3068\u3053\u308d\u306f\u306a\u304f\u3001\u300cBCA\u3067\u306f\u3001\u5e79\u7d30\u80de\u3068129\/GFP ES\u304c\u3001FES1\u3088\u308a\u3074\u3063\u305f\u3093\u3053\u3068\u8a00\u3063\u3066\u3044\u308b\u3002\u300d\u3068\u3042\u308b\u3051\u3069\u300c\u3074\u3063\u305f\u3093\u3053\u300d\u3068\u306f\u3069\u3053\u306b\u6709\u308b\u3093\u3060\u308d\uff1f
\n\u300cBCA\u8ad6\u6587\u3067\u306f\u3001\u4e0a\u8a18\u5e79\u7d30\u80de\u3068FES1\u3068\u306e\u9593\u3067SNP\u306e30%\u306f\u4e00\u81f4\u3057\u306a\u3044\u3068\u66f8\u304b\u308c\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u6842\u5831\u544a\u66f8\u306b\u306f\u3001\u3053\u3053\u307e\u3067\u66f8\u3044\u3066\u3044\u306a\u3044\u3002\u300d\u3068\u3042\u308b\u3051\u3069BCA\u8ad6\u6587\u306e\u300cRegarding these SNPs, STAP cell lines FLS3 and CTS1 and 129\/GFP ES cells are nearly identical, but differ slightly from FES1 (at 30% of these alleles), suggesting that STAP cell lines FLS and CTS were derived from a sub-stock of FES1 ES cells.\u300d\u3053\u3068\u306a\u3093\u3060\u308d\u3046\u306d\u3002differ slightly \u3092\u7121\u8996\u3057\u3066\u3001\u7d50\u8ad6\u304c\u3069\u3061\u3089\u3082\u540c\u3058\u3053\u3068\u3092\u3042\u3048\u3066\u66f8\u304b\u304f\u3053\u3068\u306a\u3057\u306b\u3001\u9055\u3044\u304c\u3042\u308b\u3068\u5f37\u8abf\u3059\u308b\u308f\u3051\u3060\u3002<\/p>\n

\u3068\u3044\u3046\u308f\u3051\u3067\u3001\u79d1\u5b66\u7684\u8b70\u8ad6\u3092\u671f\u5f85\u3057\u305f\u306e\u306b\u3001\u4f53\u5185\u6642\u8a08\u3055\u3093\u304c\u304a\u3063\u3057\u3083\u308b<\/a>\u3088\u3046\u306b\u300c\u7d50\u5c40\u3001\u5b66\u3055\u3093\u306f\u81ea\u5206\u306e\u4e3b\u5f35\u306b\u90fd\u5408\u304c\u3044\u3044\u610f\u898b\u304c\u51fa\u3066\u304f\u308b\u306e\u3092\u5f85\u3063\u3066\u3001\u305d\u308c\u3092\u300c\u79d1\u5b66\u300d\u3060\u3068\u9a12\u304e\u305f\u3044\u306e\u3060\u3068\u601d\u3044\u307e\u3059\u3002\u300d\u306a\u3093\u3067\u3059\u306a\u3002<\/p>\n

\"\"<\/a>
\n\u767e\u65e5\u7d05\uff08\u3055\u308b\u3059\u3079\u308a\uff09<\/p>\n","protected":false},"excerpt":{"rendered":"

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